Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   ODS73_RS10965 Genome accession   NZ_CP107038
Coordinates   2082195..2083136 (-) Length   313 a.a.
NCBI ID   WP_284060572.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BM6001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2077195..2088136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODS73_RS10935 (ODS73_10925) - 2077692..2077904 (-) 213 WP_050079413.1 helix-turn-helix transcriptional regulator -
  ODS73_RS10940 (ODS73_10930) - 2078070..2078801 (+) 732 WP_284060571.1 XRE family transcriptional regulator -
  ODS73_RS10945 (ODS73_10935) - 2078844..2079566 (+) 723 WP_050079417.1 hypothetical protein -
  ODS73_RS10950 (ODS73_10940) - 2079704..2081149 (+) 1446 WP_050079419.1 recombinase family protein -
  ODS73_RS10960 (ODS73_10950) comGB/cglB 2081231..2082247 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  ODS73_RS10965 (ODS73_10955) comGA/cglA/cilD 2082195..2083136 (-) 942 WP_284060572.1 competence type IV pilus ATPase ComGA Machinery gene
  ODS73_RS10970 (ODS73_10960) - 2083212..2083577 (-) 366 WP_000286415.1 DUF1033 family protein -
  ODS73_RS10975 (ODS73_10965) - 2083728..2084786 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  ODS73_RS10980 (ODS73_10970) nagA 2084948..2086099 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  ODS73_RS10985 (ODS73_10975) - 2086252..2088069 (-) 1818 WP_050214261.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35545.43 Da        Isoelectric Point: 6.0083

>NTDB_id=640176 ODS73_RS10965 WP_284060572.1 2082195..2083136(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain BM6001]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
AMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=640176 ODS73_RS10965 WP_284060572.1 2082195..2083136(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain BM6001]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATCTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGGCTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GCTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCATGCTAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.042

100

0.99
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.042

100

0.99
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.166

100

0.962
  comGA Streptococcus gordonii str. Challis substr. CH1

77.419

99.042

0.767
  comGA Streptococcus mutans UA159

65.595

99.361

0.652
  comGA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.487

99.681

0.543