Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   ODS73_RS10960 Genome accession   NZ_CP107038
Coordinates   2081231..2082247 (-) Length   338 a.a.
NCBI ID   WP_013193332.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BM6001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2076231..2087247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODS73_RS10920 (ODS73_10910) - 2076330..2076683 (-) 354 WP_044812721.1 DNA-binding protein -
  ODS73_RS10925 (ODS73_10915) - 2076693..2076851 (-) 159 WP_162837231.1 BOW99_gp33 family protein -
  ODS73_RS10930 (ODS73_10920) - 2076923..2077639 (-) 717 WP_001004043.1 phage antirepressor KilAC domain-containing protein -
  ODS73_RS10935 (ODS73_10925) - 2077692..2077904 (-) 213 WP_050079413.1 helix-turn-helix transcriptional regulator -
  ODS73_RS10940 (ODS73_10930) - 2078070..2078801 (+) 732 WP_284060571.1 XRE family transcriptional regulator -
  ODS73_RS10945 (ODS73_10935) - 2078844..2079566 (+) 723 WP_050079417.1 hypothetical protein -
  ODS73_RS10950 (ODS73_10940) - 2079704..2081149 (+) 1446 WP_050079419.1 recombinase family protein -
  ODS73_RS10960 (ODS73_10950) comGB/cglB 2081231..2082247 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  ODS73_RS10965 (ODS73_10955) comGA/cglA/cilD 2082195..2083136 (-) 942 WP_284060572.1 competence type IV pilus ATPase ComGA Machinery gene
  ODS73_RS10970 (ODS73_10960) - 2083212..2083577 (-) 366 WP_000286415.1 DUF1033 family protein -
  ODS73_RS10975 (ODS73_10965) - 2083728..2084786 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  ODS73_RS10980 (ODS73_10970) nagA 2084948..2086099 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38524.60 Da        Isoelectric Point: 9.6162

>NTDB_id=640175 ODS73_RS10960 WP_013193332.1 2081231..2082247(-) (comGB/cglB) [Streptococcus pneumoniae strain BM6001]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=640175 ODS73_RS10960 WP_013193332.1 2081231..2082247(-) (comGB/cglB) [Streptococcus pneumoniae strain BM6001]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TAACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCATTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTTTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

99.112

100

0.991
  comGB/cglB Streptococcus pneumoniae D39

99.112

100

0.991
  comGB/cglB Streptococcus pneumoniae R6

99.112

100

0.991
  comGB/cglB Streptococcus pneumoniae TIGR4

99.112

100

0.991
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.379

100

0.944
  comGB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comGB Streptococcus mutans UA140

58.176

94.083

0.547
  comGB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503