Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   LXA46_RS09830 Genome accession   NZ_CP089948
Coordinates   1946444..1947385 (-) Length   313 a.a.
NCBI ID   WP_000249564.1    Uniprot ID   Q8DN86
Organism   Streptococcus pneumoniae TIGR4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1941444..1952385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS09790 (LXA46_09775) comYH 1941930..1942883 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  LXA46_RS09795 (LXA46_09780) - 1942944..1943538 (-) 595 Protein_1935 methyltransferase domain-containing protein -
  LXA46_RS09800 (LXA46_09785) comGG/cglG 1943675..1944088 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  LXA46_RS09805 (LXA46_09790) comGF/cglF 1944066..1944527 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  LXA46_RS09810 (LXA46_09795) comGE/cglE 1944490..1944792 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LXA46_RS09815 (LXA46_09800) comGD/cglD 1944755..1945159 (-) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  LXA46_RS09820 (LXA46_09805) comGC/cglC 1945152..1945478 (-) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  LXA46_RS09825 (LXA46_09810) comGB/cglB 1945480..1946496 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  LXA46_RS09830 (LXA46_09815) comGA/cglA/cilD 1946444..1947385 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  LXA46_RS09835 (LXA46_09820) - 1947461..1947826 (-) 366 WP_000286415.1 DUF1033 family protein -
  LXA46_RS09840 (LXA46_09825) - 1947977..1949035 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  LXA46_RS09845 (LXA46_09830) nagA 1949198..1950349 (-) 1152 WP_001134456.1 N-acetylglucosamine-6-phosphate deacetylase -
  LXA46_RS09850 (LXA46_09835) - 1950502..1952319 (-) 1818 WP_001220853.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35555.47 Da        Isoelectric Point: 6.1330

>NTDB_id=639368 LXA46_RS09830 WP_000249564.1 1946444..1947385(-) (comGA/cglA/cilD) [Streptococcus pneumoniae TIGR4]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDHKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=639368 LXA46_RS09830 WP_000249564.1 1946444..1947385(-) (comGA/cglA/cilD) [Streptococcus pneumoniae TIGR4]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATCTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCATAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DN86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.