Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   LXA46_RS09825 Genome accession   NZ_CP089948
Coordinates   1945480..1946496 (-) Length   338 a.a.
NCBI ID   WP_074196785.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TIGR4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1940480..1951496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS10975 - 1940557..1940688 (-) 132 WP_000768904.1 hypothetical protein -
  LXA46_RS09785 (LXA46_09770) - 1940689..1941879 (-) 1191 WP_000167757.1 acetate kinase -
  LXA46_RS09790 (LXA46_09775) comYH 1941930..1942883 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  LXA46_RS09795 (LXA46_09780) - 1942944..1943538 (-) 595 Protein_1935 methyltransferase domain-containing protein -
  LXA46_RS09800 (LXA46_09785) comGG/cglG 1943675..1944088 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  LXA46_RS09805 (LXA46_09790) comGF/cglF 1944066..1944527 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  LXA46_RS09810 (LXA46_09795) comGE/cglE 1944490..1944792 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LXA46_RS09815 (LXA46_09800) comGD/cglD 1944755..1945159 (-) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  LXA46_RS09820 (LXA46_09805) comGC/cglC 1945152..1945478 (-) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  LXA46_RS09825 (LXA46_09810) comGB/cglB 1945480..1946496 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  LXA46_RS09830 (LXA46_09815) comGA/cglA/cilD 1946444..1947385 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  LXA46_RS09835 (LXA46_09820) - 1947461..1947826 (-) 366 WP_000286415.1 DUF1033 family protein -
  LXA46_RS09840 (LXA46_09825) - 1947977..1949035 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  LXA46_RS09845 (LXA46_09830) nagA 1949198..1950349 (-) 1152 WP_001134456.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38392.40 Da        Isoelectric Point: 9.4802

>NTDB_id=639367 LXA46_RS09825 WP_074196785.1 1945480..1946496(-) (comGB/cglB) [Streptococcus pneumoniae TIGR4]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEV
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=639367 LXA46_RS09825 WP_074196785.1 1945480..1946496(-) (comGB/cglB) [Streptococcus pneumoniae TIGR4]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTCACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAGTC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

100

100

1
  comGB/cglB Streptococcus pneumoniae D39

100

100

1
  comGB/cglB Streptococcus pneumoniae R6

100

100

1
  comGB/cglB Streptococcus pneumoniae TIGR4

100

100

1
  comGB/cglB Streptococcus mitis SK321

95.266

100

0.953
  comGB/cglB Streptococcus mitis NCTC 12261

94.675

100

0.947
  comYB Streptococcus gordonii str. Challis substr. CH1

71.131

99.408

0.707
  comYB Streptococcus mutans UA140

57.547

94.083

0.541
  comYB Streptococcus mutans UA159

57.547

94.083

0.541
  comGB Lactococcus lactis subsp. cremoris KW2

51.198

98.817

0.506