Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   N596_RS06700 Genome accession   NC_022584
Coordinates   1444497..1445765 (-) Length   422 a.a.
NCBI ID   WP_023027383.1    Uniprot ID   A0A7X2VK94
Organism   Streptococcus ilei     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1439497..1450765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS06665 (N596_06850) - 1440326..1440637 (-) 312 WP_006595405.1 DUF1292 domain-containing protein -
  N596_RS06670 (N596_06855) ruvX 1440655..1441074 (-) 420 WP_023027379.1 Holliday junction resolvase RuvX -
  N596_RS06675 (N596_06860) - 1441074..1441340 (-) 267 WP_006597020.1 IreB family regulatory phosphoprotein -
  N596_RS06680 (N596_06865) - 1441483..1442034 (-) 552 WP_023027380.1 SP0191 family lipoprotein -
  N596_RS06685 (N596_06870) - 1442044..1442637 (-) 594 WP_023027381.1 SP0191 family lipoprotein -
  N596_RS06690 (N596_06875) spx 1442821..1443219 (-) 399 WP_006595399.1 transcriptional regulator Spx -
  N596_RS06695 (N596_06880) recA 1443307..1444449 (-) 1143 WP_023027382.1 recombinase RecA Machinery gene
  N596_RS06700 (N596_06885) cinA 1444497..1445765 (-) 1269 WP_023027383.1 competence/damage-inducible protein A Machinery gene
  N596_RS06705 (N596_06890) - 1445849..1446415 (-) 567 WP_023027384.1 DNA-3-methyladenine glycosylase I -
  N596_RS06710 (N596_06895) ruvA 1446425..1447018 (-) 594 WP_023027385.1 Holliday junction branch migration protein RuvA -
  N596_RS06715 (N596_06900) mutL 1447039..1448988 (-) 1950 WP_023027386.1 DNA mismatch repair endonuclease MutL -
  N596_RS06720 (N596_06905) - 1449242..1449679 (+) 438 WP_023027387.1 LytTR family DNA-binding domain-containing protein -
  N596_RS06725 (N596_06910) - 1449676..1450134 (+) 459 WP_023027388.1 DUF3021 domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45092.56 Da        Isoelectric Point: 4.7884

>NTDB_id=62961 N596_RS06700 WP_023027383.1 1444497..1445765(-) (cinA) [Streptococcus ilei]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAGLGIDVYFQTAVGDNADRLLSVLAIARDRSDLVILTGGLGPTEDDLTKQT
LAQFLGRDLTFDPEAMAKLDRFFASRPEHIRTPNNLRQAQIVTGSTPLQNLTGLAVGGLIEVEGVSYVVLPGPPSELKPM
VTDELVPLLATGEKLYSRVLRFFGIGESQLVTVLADVIDGQTDPTVAPYAKTGEVTLRLSTKAASQEQADQKLDQLEQVI
LRHETLDGQALSQLFYGYGDDNSLAKVAFELLRERGLTLTAAESLTAGMFQSTLANFSGASAVLPGGFVTYSIEEKSKML
QIPLAELQEHGVVSAHTAERMAAQARLLTGADYGVSLTGVAGPDSLEGHPAGTVFIGIAGPKGVQSIKVNIAGRSRMDVR
KVAVLHAFNLVRRTVLLDENLL

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=62961 N596_RS06700 WP_023027383.1 1444497..1445765(-) (cinA) [Streptococcus ilei]
ATGAAAGCAGAGATCATTGCAGTGGGAACTGAAATTCTCACAGGACAGATTGTCAATACCAATGCGCAATTCTTATCAGA
AAAGTTGGCCGGTCTAGGGATCGACGTTTATTTCCAAACTGCAGTTGGGGATAATGCCGATCGTCTCTTGTCTGTTCTTG
CGATTGCGCGTGATCGAAGTGATCTCGTCATCCTCACGGGAGGCCTCGGACCGACCGAAGACGACCTGACCAAGCAGACC
CTAGCGCAGTTCTTGGGTAGAGACCTGACCTTTGATCCAGAAGCAATGGCCAAGTTGGACCGCTTCTTTGCCAGTCGGCC
AGAACATATCCGAACTCCCAACAATCTGAGACAAGCGCAAATAGTGACAGGCTCAACACCGCTCCAAAATTTGACTGGTT
TGGCAGTGGGAGGGTTGATTGAAGTAGAGGGCGTTAGCTATGTGGTCTTGCCTGGTCCCCCTAGTGAACTGAAACCTATG
GTTACTGATGAGTTAGTGCCCCTTCTAGCCACAGGCGAGAAGCTCTACTCACGCGTCTTGCGCTTTTTTGGAATCGGGGA
AAGCCAGCTGGTAACCGTTCTAGCCGATGTGATTGATGGCCAGACTGACCCGACGGTGGCTCCTTATGCCAAGACCGGAG
AAGTGACCTTGCGCTTGTCGACCAAGGCTGCGTCACAAGAGCAGGCTGATCAGAAATTGGATCAGTTGGAGCAAGTGATC
CTTCGTCATGAGACTTTAGATGGTCAAGCCTTGAGCCAGCTCTTCTATGGCTATGGAGATGACAATTCCCTAGCTAAGGT
TGCTTTTGAACTCTTGCGAGAGAGAGGTTTGACCCTAACCGCAGCAGAGAGCTTGACAGCCGGGATGTTCCAATCGACTC
TGGCTAATTTCTCAGGAGCCTCAGCAGTCCTACCAGGAGGTTTCGTCACCTACAGCATAGAGGAAAAGAGCAAAATGCTC
CAAATCCCCCTAGCTGAGTTGCAAGAACATGGAGTGGTCTCTGCCCATACAGCTGAGCGGATGGCGGCGCAAGCCCGTCT
CTTAACAGGGGCTGATTATGGAGTTAGTCTGACAGGTGTTGCTGGCCCAGACAGTCTAGAAGGCCACCCAGCAGGGACCG
TTTTTATTGGAATTGCAGGTCCTAAAGGAGTCCAATCGATCAAGGTCAATATCGCTGGCCGGAGTCGTATGGATGTTCGG
AAAGTTGCAGTCCTCCATGCCTTTAATCTGGTACGCCGGACTGTATTATTAGATGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7X2VK94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

72.488

99.052

0.718
  cinA Streptococcus mitis NCTC 12261

71.292

99.052

0.706
  cinA Streptococcus pneumoniae TIGR4

71.292

99.052

0.706
  cinA Streptococcus pneumoniae Rx1

71.292

99.052

0.706
  cinA Streptococcus pneumoniae R6

71.292

99.052

0.706
  cinA Streptococcus pneumoniae D39

71.053

99.052

0.704
  cinA Streptococcus mutans UA159

69.976

100

0.701
  cinA Streptococcus suis isolate S10

54.61

100

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

47.101

98.104

0.462

Multiple sequence alignment