Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   N597_RS08855 Genome accession   NC_022582
Coordinates   1877932..1878684 (-) Length   250 a.a.
NCBI ID   WP_023024804.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1872932..1883684
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N597_RS08835 (N597_09085) - 1873226..1874848 (+) 1623 WP_023024800.1 ATP-binding cassette domain-containing protein -
  N597_RS08840 (N597_09090) - 1874911..1877499 (+) 2589 WP_023024802.1 YfhO family protein -
  N597_RS08855 (N597_09105) comE/comE2 1877932..1878684 (-) 753 WP_023024804.1 response regulator transcription factor Regulator
  N597_RS10645 (N597_09110) - 1878685..1880004 (-) 1320 WP_023024806.1 sensor histidine kinase -
  N597_RS10020 (N597_09115) - 1880004..1880147 (-) 144 WP_023024808.1 bacteriocin -
  N597_RS08870 (N597_09125) rlmH 1880505..1880984 (-) 480 WP_023024810.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  N597_RS08875 (N597_09130) htrA 1881187..1882365 (+) 1179 WP_023024812.1 S1C family serine protease Regulator
  N597_RS08880 (N597_09135) spo0J 1882431..1883192 (+) 762 WP_023024814.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29425.19 Da        Isoelectric Point: 8.4063

>NTDB_id=62928 N597_RS08855 WP_023024804.1 1877932..1878684(-) (comE/comE2) [Streptococcus ilei]
MNIVLLEDEISQQVRVEKHVKAIAEEEGLRLNIVSTSKITELKEYLTNGDFHQLFFLDIDIKGDEKAGIKAAQMIREVNP
FAIIAFITTKSEFATITYRYKVSALEFIEKTLNENLFKEKIRECILYLKKNVIENKNIVDFFEYSFKNMEIRVPYRDILY
IETTGVSHKLRLVGKNFQKEFLGTIKDILEKDVDNHFFSPNQSYLVNQRMIVNFDRRKRLLMLEEETTCPVSRTQVKKVE
ELLNKIQKKA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=62928 N597_RS08855 WP_023024804.1 1877932..1878684(-) (comE/comE2) [Streptococcus ilei]
ATGAATATTGTATTGCTAGAGGACGAAATTTCTCAACAAGTTCGAGTAGAGAAACATGTGAAAGCTATCGCTGAGGAGGA
AGGCCTACGATTAAATATTGTTTCAACCAGTAAAATAACTGAACTAAAGGAATATCTAACCAATGGTGATTTTCATCAGC
TTTTCTTCCTTGACATTGATATCAAAGGGGATGAAAAAGCTGGTATCAAGGCAGCTCAAATGATTCGTGAAGTTAATCCT
TTTGCGATTATTGCCTTTATCACGACGAAATCGGAATTTGCTACCATTACCTATCGTTACAAGGTATCAGCTCTCGAATT
TATTGAAAAAACCTTGAATGAAAACTTGTTTAAAGAAAAAATTCGAGAATGTATTCTCTACTTGAAGAAGAATGTGATTG
AAAATAAAAATATCGTTGATTTCTTTGAGTATAGTTTCAAAAATATGGAAATTCGAGTTCCATATCGAGATATATTGTAC
ATTGAGACAACTGGAGTTTCCCACAAATTGCGACTTGTTGGAAAGAATTTTCAAAAGGAATTTTTAGGGACTATCAAGGA
TATACTTGAAAAAGATGTAGACAATCATTTCTTCAGTCCCAATCAGTCCTATCTAGTGAATCAAAGAATGATTGTCAACT
TTGATCGTCGCAAGAGACTCTTGATGTTAGAAGAGGAGACAACTTGCCCTGTCTCTCGTACACAGGTGAAAAAGGTCGAA
GAATTATTAAATAAAATACAGAAAAAGGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(18-121)

LytTr DNA-binding domain (LytTR)

(151-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

50.4

100

0.504
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

50.4

100

0.504
  comE Streptococcus infantis strain Atu-4

49.6

100

0.496
  comE Streptococcus mitis SK321

48.4

100

0.484
  comE Streptococcus mitis NCTC 12261

48.4

100

0.484
  comE Streptococcus pneumoniae Rx1

47.6

100

0.476
  comE Streptococcus pneumoniae D39

47.6

100

0.476
  comE Streptococcus pneumoniae R6

47.6

100

0.476
  comE Streptococcus pneumoniae TIGR4

47.6

100

0.476
  comE/comE1 Streptococcus equinus JB1

38.211

98.4

0.376

Multiple sequence alignment