Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   LL046_RS11360 Genome accession   NZ_CP086088
Coordinates   2219011..2219280 (-) Length   89 a.a.
NCBI ID   WP_023349160.1    Uniprot ID   A0AB35KDE0
Organism   Lactococcus lactis subsp. lactis strain EIP13A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2215349..2256114 2219011..2219280 within 0


Gene organization within MGE regions


Location: 2215349..2256114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL046_RS11325 (LL046_11290) - 2215349..2216086 (-) 738 WP_240819121.1 metal ABC transporter ATP-binding protein -
  LL046_RS11330 (LL046_11295) - 2216263..2217105 (-) 843 WP_017865154.1 metal ABC transporter substrate-binding protein -
  LL046_RS11335 (LL046_11300) - 2217102..2217539 (-) 438 WP_010906313.1 zinc-dependent MarR family transcriptional regulator -
  LL046_RS11340 (LL046_11305) comGG 2217620..2217904 (-) 285 WP_017865155.1 competence type IV pilus minor pilin ComGG Machinery gene
  LL046_RS11345 (LL046_11310) comGF 2217943..2218389 (-) 447 WP_032948129.1 competence type IV pilus minor pilin ComGF Machinery gene
  LL046_RS11350 (LL046_11315) comGE 2218352..2218648 (-) 297 WP_017865157.1 competence type IV pilus minor pilin ComGE Machinery gene
  LL046_RS11355 (LL046_11320) comGD 2218620..2219051 (-) 432 WP_026138965.1 competence type IV pilus minor pilin ComGD Machinery gene
  LL046_RS11360 (LL046_11325) comGC 2219011..2219280 (-) 270 WP_023349160.1 competence type IV pilus major pilin ComGC Machinery gene
  LL046_RS11370 (LL046_11335) - 2219863..2220642 (-) 780 WP_240819119.1 peptidoglycan amidohydrolase family protein -
  LL046_RS11375 (LL046_11340) - 2220642..2220917 (-) 276 WP_240819117.1 holin -
  LL046_RS11380 (LL046_11345) - 2220901..2221230 (-) 330 WP_240819115.1 hypothetical protein -
  LL046_RS11385 (LL046_11350) - 2221243..2221479 (-) 237 WP_394535571.1 hypothetical protein -
  LL046_RS11390 (LL046_11355) - 2221488..2223140 (-) 1653 WP_394535572.1 hypothetical protein -
  LL046_RS11395 (LL046_11360) - 2223118..2223291 (-) 174 WP_240819270.1 hypothetical protein -
  LL046_RS11400 (LL046_11365) - 2223291..2224412 (-) 1122 WP_240819268.1 hypothetical protein -
  LL046_RS11405 (LL046_11370) - 2224428..2226239 (-) 1812 WP_240819266.1 phage tail protein -
  LL046_RS11410 (LL046_11375) - 2226218..2227744 (-) 1527 WP_240819263.1 distal tail protein Dit -
  LL046_RS11415 (LL046_11380) - 2227754..2230363 (-) 2610 WP_240819261.1 phage tail tape measure protein -
  LL046_RS11420 (LL046_11385) - 2230353..2231060 (-) 708 WP_003131324.1 Gp15 family bacteriophage protein -
  LL046_RS11425 (LL046_11390) - 2231076..2231483 (-) 408 WP_003131323.1 hypothetical protein -
  LL046_RS11430 (LL046_11395) - 2231540..2232016 (-) 477 WP_014570559.1 phage tail tube protein -
  LL046_RS11435 (LL046_11400) - 2232027..2232461 (-) 435 WP_003131321.1 minor capsid protein -
  LL046_RS11440 (LL046_11405) - 2232461..2232790 (-) 330 WP_003131320.1 hypothetical protein -
  LL046_RS11445 (LL046_11410) - 2232787..2233131 (-) 345 WP_014570557.1 putative minor capsid protein -
  LL046_RS11450 (LL046_11415) - 2233121..2233522 (-) 402 WP_240819259.1 hypothetical protein -
  LL046_RS11455 (LL046_11420) - 2233596..2233832 (-) 237 WP_014570555.1 Ig-like domain-containing protein -
  LL046_RS11460 (LL046_11425) - 2233861..2234778 (-) 918 WP_003131315.1 hypothetical protein -
  LL046_RS11465 (LL046_11430) - 2234793..2235845 (-) 1053 WP_137016559.1 XkdF-like putative serine protease domain-containing protein -
  LL046_RS11470 (LL046_11435) - 2235861..2236691 (-) 831 WP_014570553.1 phage minor head protein -
  LL046_RS11475 (LL046_11440) - 2236684..2238213 (-) 1530 WP_014570552.1 phage portal protein -
  LL046_RS11480 (LL046_11445) terL 2238226..2239677 (-) 1452 WP_240819257.1 phage terminase large subunit -
  LL046_RS11485 (LL046_11450) - 2239658..2240467 (-) 810 WP_095345918.1 HNH endonuclease -
  LL046_RS11490 (LL046_11455) - 2240639..2241028 (-) 390 WP_003131303.1 DUF722 domain-containing protein -
  LL046_RS11495 (LL046_11460) - 2241111..2241425 (-) 315 WP_240819255.1 hypothetical protein -
  LL046_RS11500 (LL046_11465) - 2241422..2241604 (-) 183 WP_240819253.1 hypothetical protein -
  LL046_RS11505 (LL046_11470) - 2241650..2242003 (-) 354 WP_058224328.1 hypothetical protein -
  LL046_RS11510 (LL046_11475) - 2242000..2242188 (-) 189 WP_240819251.1 DUF1660 domain-containing protein -
  LL046_RS11515 (LL046_11480) - 2242185..2242415 (-) 231 WP_240819248.1 hypothetical protein -
  LL046_RS11520 (LL046_11485) - 2242434..2242769 (-) 336 WP_240819246.1 DUF1140 family protein -
  LL046_RS11525 (LL046_11490) - 2242766..2243152 (-) 387 WP_240819245.1 hypothetical protein -
  LL046_RS11530 - 2243145..2243267 (-) 123 WP_259743407.1 hypothetical protein -
  LL046_RS11535 (LL046_11495) - 2243260..2243457 (-) 198 WP_240819243.1 hypothetical protein -
  LL046_RS11540 (LL046_11500) - 2243454..2243825 (-) 372 WP_240819241.1 hypothetical protein -
  LL046_RS11545 (LL046_11505) - 2243822..2244451 (-) 630 WP_240819239.1 DUF1642 domain-containing protein -
  LL046_RS11550 (LL046_11510) - 2244444..2244596 (-) 153 WP_015967991.1 hypothetical protein -
  LL046_RS11555 (LL046_11515) - 2244589..2244948 (-) 360 WP_240819237.1 hypothetical protein -
  LL046_RS11560 (LL046_11520) - 2244957..2245466 (-) 510 WP_240819236.1 hypothetical protein -
  LL046_RS11565 (LL046_11525) - 2245481..2245813 (-) 333 WP_240819235.1 hypothetical protein -
  LL046_RS11570 (LL046_11530) - 2245918..2246310 (-) 393 WP_240819234.1 RusA family crossover junction endodeoxyribonuclease -
  LL046_RS11575 (LL046_11535) - 2246346..2246588 (-) 243 WP_240819233.1 hypothetical protein -
  LL046_RS11580 (LL046_11540) - 2246581..2247507 (-) 927 WP_240819232.1 phage replisome organizer N-terminal domain-containing protein -
  LL046_RS11585 (LL046_11545) - 2247772..2248698 (-) 927 WP_101961531.1 RecT family recombinase -
  LL046_RS11590 (LL046_11550) - 2248695..2249528 (-) 834 WP_240819231.1 hypothetical protein -
  LL046_RS11595 (LL046_11555) - 2249632..2249880 (-) 249 WP_029344340.1 hypothetical protein -
  LL046_RS11600 - 2249893..2250015 (-) 123 WP_023164646.1 hypothetical protein -
  LL046_RS11605 (LL046_11560) - 2250012..2250194 (-) 183 WP_003130605.1 hypothetical protein -
  LL046_RS11610 (LL046_11565) - 2250210..2250911 (-) 702 WP_240819230.1 Rha family transcriptional regulator -
  LL046_RS11615 (LL046_11570) - 2250971..2251204 (+) 234 WP_168784908.1 hypothetical protein -
  LL046_RS11620 - 2251201..2251326 (-) 126 WP_259743439.1 hypothetical protein -
  LL046_RS11625 (LL046_11575) - 2251372..2251593 (-) 222 WP_172758712.1 helix-turn-helix transcriptional regulator -
  LL046_RS11630 (LL046_11580) - 2251749..2252171 (+) 423 WP_240819228.1 helix-turn-helix transcriptional regulator -
  LL046_RS11635 (LL046_11585) - 2252182..2252766 (+) 585 WP_014570821.1 hypothetical protein -
  LL046_RS11640 (LL046_11590) - 2252822..2253361 (+) 540 WP_023189015.1 PH domain-containing protein -
  LL046_RS11645 (LL046_11595) - 2253487..2254944 (+) 1458 WP_240819271.1 recombinase family protein -

Sequence

Protein


Download         Length: 89 a.a.        Molecular weight: 10113.52 Da        Isoelectric Point: 4.2950

>NTDB_id=622452 LL046_RS11360 WP_023349160.1 2219011..2219280(-) (comGC) [Lactococcus lactis subsp. lactis strain EIP13A]
MLIVLAIISILILLFVPNLIKEKSQVQKTGEAAVVKVVESQAQLYELDHDDEKPSLSELLSAGMITQKQISAYDNYYDQN
KNEERNFND

Nucleotide


Download         Length: 270 bp        

>NTDB_id=622452 LL046_RS11360 WP_023349160.1 2219011..2219280(-) (comGC) [Lactococcus lactis subsp. lactis strain EIP13A]
ATGTTAATTGTACTAGCTATTATTAGTATTTTGATATTACTATTTGTTCCAAATTTAATTAAAGAAAAATCACAAGTTCA
AAAAACTGGAGAAGCGGCAGTTGTAAAAGTAGTAGAAAGTCAAGCTCAACTTTATGAATTAGATCATGATGATGAGAAGC
CGAGTCTGTCAGAATTGCTCAGCGCTGGGATGATTACTCAAAAACAAATTTCTGCTTACGATAATTACTATGATCAGAAT
AAAAATGAAGAACGAAATTTTAATGACTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Lactococcus lactis subsp. cremoris KW2

88

84.27

0.742
  comYC Streptococcus gordonii str. Challis substr. CH1

57.647

95.506

0.551
  comGC/cglC Streptococcus pneumoniae Rx1

55.056

100

0.551
  comGC/cglC Streptococcus pneumoniae D39

55.056

100

0.551
  comGC/cglC Streptococcus pneumoniae R6

55.056

100

0.551
  comGC/cglC Streptococcus pneumoniae TIGR4

55.056

100

0.551
  comYC Streptococcus suis isolate S10

58.904

82.022

0.483
  comGC/cglC Streptococcus mitis SK321

55.263

85.393

0.472
  comYC Streptococcus mutans UA140

52.055

82.022

0.427
  comYC Streptococcus mutans UA159

52.055

82.022

0.427
  comGC/cglC Streptococcus mitis NCTC 12261

57.812

71.91

0.416