Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   N646_RS07800 Genome accession   NC_022349
Coordinates   1736253..1737476 (+) Length   407 a.a.
NCBI ID   WP_017820393.1    Uniprot ID   -
Organism   Vibrio alginolyticus NBRC 15630 = ATCC 17749     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1731253..1742476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N646_RS07780 (N646_1614) ampD 1732301..1732852 (-) 552 WP_005386614.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  N646_RS07785 (N646_1615) nadC 1732945..1733832 (+) 888 WP_017820396.1 carboxylating nicotinate-nucleotide diphosphorylase -
  N646_RS07790 (N646_1616) - 1734094..1734531 (+) 438 WP_017820395.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  N646_RS07795 (N646_1617) pilB 1734544..1736229 (+) 1686 WP_017820394.1 type IV-A pilus assembly ATPase PilB Machinery gene
  N646_RS07800 (N646_1618) pilC 1736253..1737476 (+) 1224 WP_017820393.1 type II secretion system F family protein Machinery gene
  N646_RS07805 (N646_1619) pilD 1737541..1738410 (+) 870 WP_017635919.1 A24 family peptidase Machinery gene
  N646_RS07810 (N646_1620) coaE 1738411..1739025 (+) 615 WP_017635920.1 dephospho-CoA kinase -
  N646_RS07815 (N646_1621) zapD 1739053..1739793 (+) 741 WP_017820392.1 cell division protein ZapD -
  N646_RS07820 (N646_1622) yacG 1739952..1740146 (+) 195 WP_017635922.1 DNA gyrase inhibitor YacG -
  N646_RS07825 (N646_1623) rplS 1740611..1740964 (-) 354 WP_005379971.1 50S ribosomal protein L19 -
  N646_RS07830 (N646_1624) trmD 1741006..1741767 (-) 762 WP_005385420.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  N646_RS07835 (N646_1625) rimM 1741795..1742343 (-) 549 WP_005379964.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45310.50 Da        Isoelectric Point: 10.3992

>NTDB_id=62026 N646_RS07800 WP_017820393.1 1736253..1737476(+) (pilC) [Vibrio alginolyticus NBRC 15630 = ATCC 17749]
MKSTTPQLKNFRWKGINSSGKKTSGQTLAMTEIEVRERLDAQHIKIKKLKKSSISFLTKLNHRVKGRDITVFTRQISTML
ITGVPLVQALKLVSENHKKAEMKSILMSVTRAVEAGAPMSKAMRTASEHFDPLYTDLIATGEQSGNLAEVFERLATYREK
NEQLRAKVIKALIYPAMVVLVALGVSFIMLTKVIPEFEKMFVGFGADLPWFTRQVLDLSAWTQNWSPFIALGSISLFISA
RILSKRSDSFRLMLNRSVLKFPVLGPVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSKTSGNLHYQLAIEEVYRDTAAG
MPMYVAMRNCNVFPELVLQMVMIGEESGRLDDMLNKVATIYEFEVDNTVDNLSKILEPLIIVFLGIVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=62026 N646_RS07800 WP_017820393.1 1736253..1737476(+) (pilC) [Vibrio alginolyticus NBRC 15630 = ATCC 17749]
ATGAAAAGCACTACACCACAACTTAAAAACTTCCGCTGGAAAGGCATCAACAGTTCAGGCAAAAAGACATCTGGGCAAAC
CCTCGCGATGACAGAAATTGAAGTACGCGAGCGTCTAGACGCACAGCACATCAAGATCAAGAAGTTAAAGAAAAGCAGTA
TCTCGTTTCTCACTAAACTCAACCATCGCGTGAAAGGCAGAGACATCACGGTGTTTACCCGTCAGATTTCGACGATGTTG
ATAACCGGTGTACCCTTAGTTCAGGCTTTAAAATTAGTCTCAGAAAATCATAAAAAAGCAGAGATGAAATCCATTTTGAT
GAGCGTGACACGCGCCGTTGAAGCGGGGGCGCCCATGTCAAAAGCCATGCGCACTGCAAGTGAACACTTTGACCCACTCT
ATACTGATCTTATCGCCACAGGTGAGCAATCCGGTAACTTAGCGGAAGTGTTCGAGCGCTTAGCCACCTACCGAGAAAAA
AATGAACAACTCCGTGCGAAAGTGATCAAAGCACTGATTTACCCAGCGATGGTAGTGCTAGTAGCGTTAGGCGTGTCGTT
TATCATGCTCACCAAAGTCATTCCCGAGTTCGAAAAAATGTTTGTTGGTTTTGGTGCTGACTTACCTTGGTTTACCAGGC
AAGTGTTAGATCTTTCCGCCTGGACACAAAACTGGAGTCCGTTTATCGCACTAGGCTCCATTAGTTTATTCATTTCGGCG
AGAATCCTCTCTAAGCGTTCAGATTCTTTTCGCTTAATGCTCAACCGCTCTGTGCTTAAATTTCCGGTCCTTGGGCCTGT
ATTATCAAAAGCCGCTATCGCCAAATTTAGTCGAACACTCGCCACAAGCTTTACAGCGGGTATTCCAATTCTAACCAGTT
TAAAAACCACATCAAAAACCTCAGGAAACTTACACTATCAACTCGCCATAGAAGAAGTTTACCGTGATACCGCCGCAGGT
ATGCCAATGTATGTAGCCATGCGCAACTGTAATGTGTTCCCTGAATTGGTGTTACAAATGGTTATGATCGGTGAAGAGTC
TGGTCGACTTGACGATATGCTCAATAAAGTTGCAACAATCTACGAGTTTGAAGTCGACAACACCGTCGACAACCTTAGTA
AAATCCTAGAGCCACTAATTATCGTTTTTTTAGGTATCGTTGTTGGCGGATTAGTGACAGCAATGTACTTGCCAATCTTT
AACTTAATGAGTGTATTGGGCTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

86.732

100

0.867
  pilC Vibrio cholerae strain A1552

73.529

100

0.737
  pilC Acinetobacter baylyi ADP1

43

98.28

0.423
  pilC Acinetobacter baumannii D1279779

41.439

99.017

0.41
  pilC Legionella pneumophila strain ERS1305867

40.541

100

0.405
  pilG Neisseria gonorrhoeae MS11

40.494

99.509

0.403
  pilG Neisseria meningitidis 44/76-A

40.247

99.509

0.4
  pilC Pseudomonas stutzeri DSM 10701

40.909

97.297

0.398

Multiple sequence alignment