Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   LIO34_RS00395 Genome accession   NZ_CP085085
Coordinates   68854..70035 (+) Length   393 a.a.
NCBI ID   WP_172005886.1    Uniprot ID   -
Organism   Streptococcus suis strain Ssuis_MA8     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 63854..75035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO34_RS00380 mutL 65428..67365 (+) 1938 WP_004194473.1 DNA mismatch repair endonuclease MutL -
  LIO34_RS00385 ruvA 67404..67994 (+) 591 WP_004194470.1 Holliday junction branch migration protein RuvA -
  LIO34_RS00390 - 68248..68817 (+) 570 WP_004194469.1 DNA-3-methyladenine glycosylase I -
  LIO34_RS00395 cinA 68854..70035 (+) 1182 WP_172005886.1 competence/damage-inducible protein A Machinery gene
  LIO34_RS00400 recA 70087..71238 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  LIO34_RS00405 spx 71474..71872 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  LIO34_RS00410 - 71972..72238 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  LIO34_RS00415 ruvX 72238..72657 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  LIO34_RS00420 - 72669..72989 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  LIO34_RS00425 - 73247..73825 (+) 579 WP_044667815.1 nucleotidyltransferase family protein -
  LIO34_RS00430 comX/sigX 73898..74164 (+) 267 WP_002939335.1 hypothetical protein Regulator
  LIO34_RS00435 rpsJ 74486..74794 (+) 309 WP_013730061.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43090.05 Da        Isoelectric Point: 4.4112

>NTDB_id=615143 LIO34_RS00395 WP_172005886.1 68854..70035(+) (cinA) [Streptococcus suis strain Ssuis_MA8]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQI
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLYQSQQQLYSRILRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=615143 LIO34_RS00395 WP_172005886.1 68854..70035(+) (cinA) [Streptococcus suis strain Ssuis_MA8]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTCTATTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACCTGGTCATTCTCTGTGGAGGATTGGGTCCAACTGAGGATGACTTGACCAAGCAGATC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTACCAATCTCAGCAGCAACTTTATTCGCGTATCCTACGTTTTTTTGGCATTGG
TGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATCGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTAAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

95.674

100

0.957
  cinA Streptococcus mutans UA159

56.448

100

0.59
  cinA Streptococcus mitis SK321

55.769

100

0.59
  cinA Streptococcus pneumoniae TIGR4

55.769

100

0.59
  cinA Streptococcus pneumoniae Rx1

55.769

100

0.59
  cinA Streptococcus pneumoniae R6

55.769

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.529

100

0.588
  cinA Streptococcus pneumoniae D39

55.529

100

0.588
  cinA Bacillus subtilis subsp. subtilis str. 168

40.665

99.491

0.405