Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   K6969_RS00905 Genome accession   NZ_CP082205
Coordinates   168523..169704 (+) Length   393 a.a.
NCBI ID   WP_171942863.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 163523..174704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS00890 (K6969_00865) mutL 164645..166582 (+) 1938 WP_029173229.1 DNA mismatch repair endonuclease MutL -
  K6969_RS00895 (K6969_00870) ruvA 166621..167211 (+) 591 WP_029173228.1 Holliday junction branch migration protein RuvA -
  K6969_RS00900 (K6969_00875) - 167917..168486 (+) 570 WP_029173227.1 DNA-3-methyladenine glycosylase I -
  K6969_RS00905 (K6969_00880) cinA 168523..169704 (+) 1182 WP_171942863.1 competence/damage-inducible protein A Machinery gene
  K6969_RS00910 (K6969_00885) recA 169756..170907 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  K6969_RS00915 (K6969_00890) spx 171067..171465 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  K6969_RS00920 (K6969_00895) - 171572..171838 (+) 267 WP_004195477.1 IreB family regulatory phosphoprotein -
  K6969_RS00925 (K6969_00900) ruvX 171838..172257 (+) 420 WP_099780101.1 Holliday junction resolvase RuvX -
  K6969_RS00930 (K6969_00905) - 172269..172589 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  K6969_RS00935 (K6969_00910) - 172959..173498 (+) 540 WP_253911814.1 nucleotidyltransferase family protein -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43007.00 Da        Isoelectric Point: 4.4882

>NTDB_id=600023 K6969_RS00905 WP_171942863.1 168523..169704(+) (cinA) [Streptococcus suis strain AKJ18]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASKRSELVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDNQTDPTIAPYAKVGEVTLRLSTKATSQEEADLRLNQLEED
ILQRDKLREYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALAVQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPKSTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=600023 K6969_RS00905 WP_171942863.1 168523..169704(+) (cinA) [Streptococcus suis strain AKJ18]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATCAATACCAACGCCCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTACTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTTTGTCTGTACTGG
AGGTAGCCAGCAAGCGTAGTGAGCTAGTCATTCTCTGTGGAGGACTTGGCCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGCTTCTTTGCCAGTCGCCC
AGGTCGTGTTCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
TGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATTGACAACCAAACTGACCCGACGATTGCACCCTATGCTAAGGTTG
GTGAAGTAACCTTGCGTCTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAGATTTACGTCTGAATCAGTTGGAAGAAGAC
ATCTTACAACGTGATAAACTGAGAGAATATTTCTATGCTTACGGTGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGTTCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGAAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

95.42

100

0.954
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

41.688

99.491

0.415