Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   K6974_RS00425 Genome accession   NZ_CP082204
Coordinates   72025..73206 (+) Length   393 a.a.
NCBI ID   WP_222337357.1    Uniprot ID   -
Organism   Streptococcus suis strain FJSM5     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 67025..78206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6974_RS00400 (K6974_00390) mutL 67130..69067 (+) 1938 WP_222337361.1 DNA mismatch repair endonuclease MutL -
  K6974_RS00405 (K6974_00395) - 69141..69506 (+) 366 WP_222337360.1 helix-turn-helix domain-containing protein -
  K6974_RS00410 (K6974_00400) - 69521..70168 (+) 648 WP_222337359.1 CPBP family intramembrane glutamic endopeptidase -
  K6974_RS00415 (K6974_00405) ruvA 70246..70836 (+) 591 WP_053863613.1 Holliday junction branch migration protein RuvA -
  K6974_RS00420 (K6974_00410) - 71419..71988 (+) 570 WP_222337358.1 DNA-3-methyladenine glycosylase I -
  K6974_RS00425 (K6974_00415) cinA 72025..73206 (+) 1182 WP_222337357.1 competence/damage-inducible protein A Machinery gene
  K6974_RS00430 (K6974_00420) recA 73258..74409 (+) 1152 WP_222337356.1 recombinase RecA Machinery gene
  K6974_RS00435 (K6974_00425) - 74605..76359 (-) 1755 WP_392338942.1 IS1634 family transposase -
  K6974_RS00440 (K6974_00430) spx 76633..77031 (+) 399 WP_004195475.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42945.87 Da        Isoelectric Point: 4.4647

>NTDB_id=599962 K6974_RS00425 WP_222337357.1 72025..73206(+) (cinA) [Streptococcus suis strain FJSM5]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNKNRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTLNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGENNSLVQTVATRLAEKRQTIAIVEQGTGGLVQAELSLALANQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLVTTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=599962 K6974_RS00425 WP_222337357.1 72025..73206(+) (cinA) [Streptococcus suis strain FJSM5]
ATGAAAGCAGAACTAATCGCCGTCGGAACCGAGATTTTGACAGGCCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTTCACACAGCTGTTGGAGATAATAAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACTAAATAATGAACGACAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGCCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGTGAAAACAATAGTCTGGTTCAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGAACGGGCGGTCTTGTGCAGGCGGAATTGAGCCTGGCTT
TGGCTAATCAGCCGTATTTTAGCGGAGGTAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGTTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGATATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTACAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

95.165

100

0.952
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus pneumoniae R6

55.529

100

0.588
  cinA Streptococcus mitis SK321

55.529

100

0.588
  cinA Streptococcus pneumoniae TIGR4

55.529

100

0.588
  cinA Streptococcus pneumoniae Rx1

55.529

100

0.588
  cinA Streptococcus mitis NCTC 12261

55.288

100

0.585
  cinA Streptococcus pneumoniae D39

55.288

100

0.585
  cinA Bacillus subtilis subsp. subtilis str. 168

39.898

99.491

0.397