Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   K6972_RS00405 Genome accession   NZ_CP082203
Coordinates   70272..71453 (+) Length   393 a.a.
NCBI ID   WP_105179975.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 65272..76453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS00390 (K6972_00390) mutL 66281..68218 (+) 1938 WP_222812617.1 DNA mismatch repair endonuclease MutL -
  K6972_RS00395 (K6972_00395) ruvA 68257..68847 (+) 591 WP_105179973.1 Holliday junction branch migration protein RuvA -
  K6972_RS00400 (K6972_00400) - 69666..70235 (+) 570 WP_105179974.1 DNA-3-methyladenine glycosylase I -
  K6972_RS00405 (K6972_00405) cinA 70272..71453 (+) 1182 WP_105179975.1 competence/damage-inducible protein A Machinery gene
  K6972_RS00410 (K6972_00410) recA 71505..72656 (+) 1152 WP_105118957.1 recombinase RecA Machinery gene
  K6972_RS00415 (K6972_00415) spx 72892..73290 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  K6972_RS00420 (K6972_00420) - 73390..73656 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  K6972_RS00425 (K6972_00425) ruvX 73656..74075 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  K6972_RS00430 (K6972_00430) - 74087..74407 (+) 321 WP_222812619.1 DUF1292 domain-containing protein -
  K6972_RS00435 (K6972_00435) - 74578..75156 (+) 579 WP_105179976.1 nucleotidyltransferase family protein -
  K6972_RS00440 (K6972_00440) rpsJ 75818..76126 (+) 309 WP_002939332.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42998.11 Da        Isoelectric Point: 4.4535

>NTDB_id=599909 K6972_RS00405 WP_105179975.1 70272..71453(+) (cinA) [Streptococcus suis strain NJ3]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMVKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILKRDKLADYFYAYGEDNSLVKMVASCLIEKKQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISKKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=599909 K6972_RS00405 WP_105179975.1 70272..71453(+) (cinA) [Streptococcus suis strain NJ3]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGCCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACTTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGTAAAATTAGACCGCTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGCCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTGCCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
TGAAAGCCAGCTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCACCCTATGCTAAGGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTGAAACGTGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAATGGTAGCGTCTTG
TTTGATAGAGAAAAAACAAACTATAGCCATCGTCGAACAGGGGACAGGTGGTCTTTTGCAAGCTGAATTGAGTTTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGGAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCAAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTTTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(258-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

94.148

100

0.941
  cinA Streptococcus mutans UA159

57.178

100

0.598
  cinA Streptococcus mitis SK321

56.49

100

0.598
  cinA Streptococcus mitis NCTC 12261

56.25

100

0.595
  cinA Streptococcus pneumoniae TIGR4

56.25

100

0.595
  cinA Streptococcus pneumoniae Rx1

56.25

100

0.595
  cinA Streptococcus pneumoniae R6

56.25

100

0.595
  cinA Streptococcus pneumoniae D39

56.01

100

0.593
  cinA Bacillus subtilis subsp. subtilis str. 168

41.432

99.491

0.412