Detailed information NTG0591586

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: ITG12_RS14070
• Genome accession: NZ_CP080238
• Coordinates: 3001054..3002277 (-)
• Length: 407 a.a.
• NCBI ID: WP_038878900.1
• Uniprot ID: -
• Organism: Vibrio sp. ED002
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2996054..3007277

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ITG12_RS14030 (ITG12_13950)	rpsP	2996156..2996404 (+)	249	WP_005438039.1	30S ribosomal protein S16	-
ITG12_RS14035 (ITG12_13955)	rimM	2996431..2996979 (+)	549	WP_038870471.1	ribosome maturation factor RimM	-
ITG12_RS14040 (ITG12_13960)	trmD	2997007..2997750 (+)	744	WP_038870473.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
ITG12_RS14045 (ITG12_13965)	rplS	2997792..2998145 (+)	354	WP_038870475.1	50S ribosomal protein L19	-
ITG12_RS14050 (ITG12_13970)	yacG	2998471..2998665 (-)	195	WP_038870477.1	DNA gyrase inhibitor YacG	-
ITG12_RS14055 (ITG12_13975)	zapD	2998730..2999470 (-)	741	WP_038870479.1	cell division protein ZapD	-
ITG12_RS14060 (ITG12_13980)	coaE	2999498..3000112 (-)	615	WP_038870481.1	dephospho-CoA kinase	-
ITG12_RS14065 (ITG12_13985)	pilD	3000113..3000982 (-)	870	WP_038870483.1	A24 family peptidase	Machinery gene
ITG12_RS14070 (ITG12_13990)	pilC	3001054..3002277 (-)	1224	WP_038878900.1	type II secretion system F family protein	Machinery gene
ITG12_RS14075 (ITG12_13995)	pilB	3002309..3003994 (-)	1686	WP_038878901.1	type IV-A pilus assembly ATPase PilB	Machinery gene
ITG12_RS14080 (ITG12_14000)	pilA	3003994..3004398 (-)	405	WP_038878904.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
ITG12_RS14085 (ITG12_14005)	nadC	3004663..3005550 (-)	888	WP_038878907.1	carboxylating nicotinate-nucleotide diphosphorylase	-
ITG12_RS14090 (ITG12_14010)	ampD	3005643..3006194 (+)	552	WP_038870491.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 44989.25 Da
• Isoelectric Point: 10.4174

>NTDB_id=591586 ITG12_RS14070 WP_038878900.1 3001054..3002277(-) (pilC) [Vibrio sp. ED002]
MKTNAPQLKSFRWKGTNSSGKKTSGQVLAMTEIEVRERLDAQHIKIKKLKKGSISFITKLSHQVKGKDITVFTRQIATML
MTGVPIVQALKLVSENHRKAEMKSILMSVTRAVEAGTPMSKAMRTASTHFDPLYTDLIATGEQSGNLPQVFERLATYREK
SEQLKAKVIKALIYPAMVVLVALGVSYLMLTKVIPEFEKMFVGFGADLPAFTQMVLNLSAWTQNWGPFIGLSALSLFISS
RIMAKRSDSFRLLLARSSLRFPILGPVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSKTSGNMHYQLAIEEVYRDTAAG
MPMYIAMRNCNVFPELVLQMVMIGEESGRLDDMLNKIAAIYEFEVDNTVDNLSKILEPLIIVFLGVVVGGLVTAMYLPIF
NLMSVLG

Nucleotide

• Length: 1224 bp

>NTDB_id=591586 ITG12_RS14070 WP_038878900.1 3001054..3002277(-) (pilC) [Vibrio sp. ED002]
ATGAAAACTAACGCCCCACAACTTAAAAGTTTCCGCTGGAAAGGCACGAACAGCTCAGGGAAGAAAACCTCCGGACAAGT
GTTAGCCATGACAGAAATTGAAGTGCGAGAACGCCTGGATGCTCAACACATTAAAATTAAGAAGCTTAAGAAAGGCAGTA
TTTCTTTTATCACGAAACTGAGTCATCAAGTCAAAGGCAAAGACATTACGGTATTTACCCGTCAAATCGCTACCATGTTA
ATGACCGGCGTTCCCATCGTTCAAGCTCTGAAGCTTGTCTCAGAAAACCATAGAAAAGCTGAGATGAAATCAATACTGAT
GAGCGTAACACGAGCAGTAGAAGCAGGTACGCCAATGTCCAAAGCCATGCGCACCGCCAGCACGCATTTTGACCCACTCT
ATACTGATTTAATCGCAACCGGTGAGCAGTCAGGTAACTTACCTCAGGTATTTGAACGTCTGGCGACTTACCGAGAAAAA
AGCGAACAATTGAAAGCAAAAGTTATCAAAGCACTCATCTATCCGGCGATGGTAGTTTTGGTCGCGCTAGGGGTCTCCTA
CCTCATGCTCACCAAAGTGATACCTGAGTTCGAAAAGATGTTTGTTGGCTTTGGCGCCGACCTGCCTGCATTTACTCAAA
TGGTCTTAAATCTTTCGGCATGGACACAAAATTGGGGGCCTTTTATTGGGCTCAGTGCATTAAGCTTATTTATTTCCTCC
CGTATCATGGCTAAACGTTCGGATTCTTTCCGATTATTGTTGGCTCGATCGAGCTTAAGATTTCCTATACTCGGCCCCGT
CTTATCCAAAGCGGCGATTGCGAAATTCAGCCGTACTCTTGCAACCAGTTTTACCGCCGGTATCCCCATTTTGACAAGCT
TAAAAACCACCTCTAAAACATCCGGTAATATGCATTATCAACTTGCCATCGAAGAGGTCTACCGAGATACCGCAGCGGGT
ATGCCAATGTACATCGCAATGCGCAATTGCAACGTATTCCCAGAATTGGTGCTGCAAATGGTAATGATCGGTGAAGAATC
CGGACGTTTAGACGATATGCTCAACAAAATTGCCGCGATCTATGAGTTTGAAGTGGATAACACCGTCGACAATCTGAGTA
AAATTTTAGAGCCGTTGATCATTGTTTTTCTTGGGGTCGTCGTTGGCGGATTGGTCACAGCAATGTACTTACCAATCTTT
AACTTAATGAGCGTATTGGGATAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (72-195)

• Type II secretion system (T2SS), protein F (T2SSF) (276-398)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Vibrio campbellii strain DS40M4	93.612	100	0.936
pilC	Vibrio cholerae strain A1552	74	98.28	0.727
pilC	Acinetobacter baylyi ADP1	43.25	98.28	0.425
pilC	Acinetobacter baumannii D1279779	41.523	100	0.415
pilC	Legionella pneumophila strain ERS1305867	40.541	100	0.405
pilC	Pseudomonas stutzeri DSM 10701	40.75	98.28	0.4
pilG	Neisseria meningitidis 44/76-A	39.356	99.263	0.391
pilG	Neisseria gonorrhoeae MS11	39.356	99.263	0.391