Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   ITG12_RS11230 Genome accession   NZ_CP080238
Coordinates   2426905..2428014 (+) Length   369 a.a.
NCBI ID   WP_061036154.1    Uniprot ID   A0A2N7MZB6
Organism   Vibrio sp. ED002     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2421905..2433014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ITG12_RS11210 (ITG12_11130) rsmB 2422822..2424105 (-) 1284 WP_020196736.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ITG12_RS11215 (ITG12_11135) fmt 2424189..2425136 (-) 948 WP_042602376.1 methionyl-tRNA formyltransferase -
  ITG12_RS11220 (ITG12_11140) def 2425170..2425688 (-) 519 WP_038870153.1 peptide deformylase -
  ITG12_RS11225 (ITG12_11145) - 2425827..2426921 (+) 1095 WP_248873072.1 LysM peptidoglycan-binding domain-containing protein -
  ITG12_RS11230 (ITG12_11150) dprA 2426905..2428014 (+) 1110 WP_061036154.1 DNA-processing protein DprA Machinery gene
  ITG12_RS11235 (ITG12_11155) - 2428017..2428496 (+) 480 WP_038870148.1 DUF494 family protein -
  ITG12_RS11240 (ITG12_11160) - 2428520..2429089 (+) 570 WP_102389345.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein -
  ITG12_RS11245 (ITG12_11165) - 2429133..2430337 (-) 1205 Protein_2106 IS3 family transposase -
  ITG12_RS11250 (ITG12_11170) - 2430448..2431581 (-) 1134 WP_248873073.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  ITG12_RS11255 (ITG12_11175) purE 2431586..2432071 (-) 486 WP_248873074.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  ITG12_RS11260 (ITG12_11180) - 2432272..2432829 (+) 558 WP_045401092.1 L-threonylcarbamoyladenylate synthase -

Sequence

Protein


Download         Length: 369 a.a.        Molecular weight: 39725.57 Da        Isoelectric Point: 6.4977

>NTDB_id=591568 ITG12_RS11230 WP_061036154.1 2426905..2428014(+) (dprA) [Vibrio sp. ED002]
MQPHNDTDLAAWLKLSCLPGIGGVKMNKLLTKDTPNNIVQYSTEQLLRLGLTMKQLQAWSEVDKEVDACLTWLASSSHHS
ILTLANPLYPPLLKQTVAPPPLLFVKGDASCLSQPQIAMVGSRNASVDGLQHARSFASELVQHDLIVTSGLALGIDGHAH
DGALMAGGKTIAVLGSGLEQVYPARHRGLAQRVMENGTLVSEFRPKAKPRAENFPRRNRIISGLSLGVLVVEAAEKSGSL
ITARYALEQGREVFALPASIHSPNASGGNQLIRNGACLVQTTQDVLNEIQSLLDWSINQSLDLFSAPIDEEELPFPQLLA
NVGNEATPVDILANRTNIPVQEVMMQLLELELSGHVVAVSGGYIRKGRG

Nucleotide


Download         Length: 1110 bp        

>NTDB_id=591568 ITG12_RS11230 WP_061036154.1 2426905..2428014(+) (dprA) [Vibrio sp. ED002]
ATGCAACCACACAATGATACCGACCTCGCTGCCTGGTTAAAGCTCAGCTGCTTACCAGGCATTGGCGGGGTTAAGATGAA
TAAGCTGCTGACCAAAGACACGCCGAATAACATTGTCCAGTACTCGACTGAACAGCTTCTCCGCCTTGGGCTGACGATGA
AACAGTTACAAGCATGGTCTGAGGTCGATAAAGAAGTCGATGCTTGTTTAACTTGGTTAGCATCCTCTTCCCATCATTCT
ATTCTCACCTTGGCGAATCCACTTTATCCTCCACTTCTTAAACAAACGGTCGCGCCACCTCCTTTATTATTTGTAAAGGG
AGATGCGAGCTGTTTGTCTCAACCGCAAATCGCCATGGTTGGTAGTCGTAATGCTAGTGTGGATGGGTTGCAACATGCTC
GTAGCTTTGCTTCAGAACTCGTACAACATGATCTGATCGTGACCAGTGGCTTGGCTTTGGGTATTGATGGTCATGCTCAT
GATGGTGCGCTTATGGCGGGCGGTAAAACTATCGCTGTCTTAGGTTCTGGGTTGGAGCAAGTGTACCCCGCCAGGCATCG
TGGTTTAGCGCAGCGTGTCATGGAGAATGGCACTCTCGTTTCGGAGTTTCGTCCAAAAGCGAAACCTCGTGCGGAAAACT
TCCCACGTCGCAATCGAATTATTAGTGGTTTGTCGTTGGGTGTATTGGTGGTGGAAGCGGCGGAAAAAAGTGGCTCCTTG
ATTACTGCTCGTTATGCTCTGGAACAAGGTCGTGAAGTATTTGCGCTTCCTGCCTCTATTCATTCGCCCAATGCGAGTGG
CGGTAATCAATTGATTCGTAACGGTGCTTGTCTCGTACAAACTACTCAAGACGTGTTAAATGAAATACAGTCACTGCTTG
ATTGGTCTATTAATCAAAGCTTAGATTTATTTTCTGCGCCAATTGATGAAGAAGAATTGCCATTTCCTCAGCTGTTAGCT
AACGTAGGAAATGAGGCTACACCAGTTGATATTCTTGCAAACAGGACCAATATACCTGTCCAAGAAGTCATGATGCAGCT
CTTAGAGCTTGAGCTTTCAGGGCATGTTGTTGCAGTATCCGGTGGCTATATTCGAAAGGGGAGGGGCTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(78-280)

DprA winged helix domain (DprA_WH)

(307-362)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2N7MZB6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

92.141

100

0.921
  dprA Vibrio cholerae strain A1552

58.378

100

0.585
  dprA Glaesserella parasuis strain SC1401

47.2

100

0.48
  dprA Legionella pneumophila strain ERS1305867

48.036

89.702

0.431
  dprA Haemophilus influenzae Rd KW20

44.706

92.141

0.412
  dprA Neisseria meningitidis strain C311

36.247

100

0.382
  dprA Neisseria meningitidis MC58

36.247

100

0.382
  dprA Neisseria gonorrhoeae MS11

35.659

100

0.374
  dprA Neisseria gonorrhoeae strain FA1090

35.401

100

0.371
  dprA Acinetobacter baylyi ADP1

40.597

90.786

0.369