Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   TL13_RS00365 Genome accession   NC_021213
Coordinates   64389..65570 (+) Length   393 a.a.
NCBI ID   WP_015646245.1    Uniprot ID   -
Organism   Streptococcus suis TL13     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 59389..70570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS00350 (TL13_0073) mutL 60781..62718 (+) 1938 WP_015646242.1 DNA mismatch repair endonuclease MutL -
  TL13_RS00355 (TL13_0074) ruvA 62757..63347 (+) 591 WP_015646243.1 Holliday junction branch migration protein RuvA -
  TL13_RS00360 (TL13_0075) - 63783..64352 (+) 570 WP_015646244.1 DNA-3-methyladenine glycosylase I -
  TL13_RS00365 (TL13_0076) cinA 64389..65570 (+) 1182 WP_015646245.1 competence/damage-inducible protein A Machinery gene
  TL13_RS00370 (TL13_0077) recA 65622..66773 (+) 1152 WP_015646246.1 recombinase RecA Machinery gene
  TL13_RS00375 (TL13_0078) spx 67009..67407 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  TL13_RS00380 (TL13_0079) - 67507..67773 (+) 267 WP_004195477.1 IreB family regulatory phosphoprotein -
  TL13_RS00385 (TL13_0080) ruvX 67773..68192 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  TL13_RS00390 (TL13_0081) - 68204..68524 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  TL13_RS00395 (TL13_0082) - 68795..69409 (+) 615 WP_015646247.1 nucleotidyltransferase family protein -
  TL13_RS00405 (TL13_0083) rpsJ 70069..70377 (+) 309 WP_014735259.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42943.84 Da        Isoelectric Point: 4.3283

>NTDB_id=58601 TL13_RS00365 WP_015646245.1 64389..65570(+) (cinA) [Streptococcus suis TL13]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMVEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEADLRLNQLEED
ILQRDKLREYFYAYGEENSLVQTVATGLVEKKQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTGLGWLSEDA
DRIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=58601 TL13_RS00365 WP_015646245.1 64389..65570(+) (cinA) [Streptococcus suis TL13]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGGTTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAGATTTGCGTCTGAATCAGTTGGAAGAAGAC
ATCTTACAACGTGATAAACTGAGAGAATATTTCTATGCTTACGGTGAAGAAAATAGCCTGGTACAAACGGTAGCGACTGG
TTTGGTTGAGAAAAAACAAACCATAGCCATTGTCGAGCAGGGGACAGGAGGGCTCTTGCAGGCAGAATTGAGTTTGGCTT
TGGCTGATCAGCCTTATTTTAGCGGAGGAAAAGTCATCGGTCAGTTAGGGACAGGATTGGGCTGGCTATCAGAAGATGCA
GATCGCATTCGACAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

94.148

100

0.941
  cinA Streptococcus mutans UA159

57.178

100

0.598
  cinA Streptococcus mitis SK321

56.25

100

0.595
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus mitis NCTC 12261

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

48.208

78.117

0.377

Multiple sequence alignment