Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   MDRSPN_RS08995 Genome accession   NZ_AP018391
Coordinates   1707292..1708548 (-) Length   418 a.a.
NCBI ID   WP_061588623.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain MDRSPN001     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1702292..1713548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MDRSPN_RS08965 (MDRSPN_01711) - 1702349..1702555 (-) 207 WP_000366087.1 hypothetical protein -
  MDRSPN_RS08970 - 1702542..1702703 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  MDRSPN_RS08975 (MDRSPN_01712) lytA 1703062..1704018 (-) 957 WP_120164273.1 N-acetylmuramoyl-L-alanine amidase LytA -
  MDRSPN_RS08980 (MDRSPN_01713) - 1704394..1705764 (-) 1371 WP_001036271.1 MATE family efflux transporter -
  MDRSPN_RS08990 (MDRSPN_01714) recA 1706071..1707237 (-) 1167 WP_120164274.1 recombinase RecA -
  MDRSPN_RS08995 (MDRSPN_01715) cinA 1707292..1708548 (-) 1257 WP_061588623.1 competence/damage-inducible protein A Machinery gene
  MDRSPN_RS09000 (MDRSPN_01716) brpA 1708622..1709659 (-) 1038 WP_120164275.1 biofilm formation/cell division transcriptional regulator BrpA -
  MDRSPN_RS09005 (MDRSPN_01717) - 1709667..1710185 (-) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  MDRSPN_RS09010 (MDRSPN_01718) tsaE 1710175..1710618 (-) 444 WP_000288230.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  MDRSPN_RS09015 (MDRSPN_01719) comM 1710704..1711324 (-) 621 WP_000839909.1 hypothetical protein Regulator
  MDRSPN_RS09025 (MDRSPN_01720) - 1711630..1712493 (-) 864 WP_001093609.1 helix-turn-helix domain-containing protein -
  MDRSPN_RS11535 (MDRSPN_01721) - 1712684..1712854 (+) 171 WP_001227863.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45068.44 Da        Isoelectric Point: 4.8315

>NTDB_id=58570 MDRSPN_RS08995 WP_061588623.1 1707292..1708548(-) (cinA) [Streptococcus pneumoniae strain MDRSPN001]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKELAFDPQSQAKLDVFFAQRPDYARTPNNERQAQLVAGSTPLPNETGLAVGGILEVDGVAYVVLPGPPSELKPM
VLNQLLPKLMTGTKLYSRVLRFFGIGESQLVTILADLIDQQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQVLDILENQI
LDRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTARKMAEQARLKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLARKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=58570 MDRSPN_RS08995 WP_061588623.1 1707292..1708548(-) (cinA) [Streptococcus pneumoniae strain MDRSPN001]
ATGAAAGCAGAAATTATTGCTGTTGGAACAGAAATTTTAACAGGGCAAATCGTCAATACCAATGCTCAGTTTTTATCAGA
GAAGCTAGCCGAAATTGGGGTAGATGTCTACTTCCAAACAGCTGTCGGAGACAATGAAGCTCGTCTCTTGTCCTTGCTTG
AGATTGCGAGCCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACTGAGGATGATTTGACCAAACAAACT
CTAGCTAAATTTTTAGGGAAAGAATTAGCCTTCGATCCTCAGTCGCAGGCAAAGTTGGATGTCTTTTTTGCTCAGAGACC
AGACTATGCGAGAACACCAAATAATGAAAGACAAGCTCAACTTGTAGCAGGGTCGACTCCACTACCAAACGAAACAGGAT
TGGCTGTTGGAGGAATCTTAGAAGTGGATGGCGTAGCCTACGTGGTCCTTCCGGGACCGCCAAGTGAGTTGAAACCCATG
GTCTTAAATCAACTTTTACCCAAGCTGATGACAGGCACCAAACTATATTCCCGAGTGCTTCGTTTCTTTGGAATTGGTGA
GAGTCAGTTGGTGACCATTTTGGCGGACTTGATTGACCAGCAAACGGATCCGACCTTGGCTCCTTATGCCAAGACGGGAG
AAGTGACTTTGCGCCTGTCTACAAAAGCAGTTAGTCAAGAAAAGGCTGATCAAGTACTAGATATCTTAGAAAATCAAATC
TTGGATCGCCAGACTTTTGAGGGAATTTCTCTGCGCGACATCTGTTATGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAGGCTACTT
TAGCAGACTTTTCAGGTGTTTCAGCTATCTTTAATGGAGGGTTTGTCACCTACAGCCTAGAAGAAAAGTCCAAGATGTTG
GATATTTCCGAGCAAGAGCTAAAAGAACACGGGGTCGTTTCTGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGCT
CAAGACTCAGTCTGATTATGGAGTCAGTCTGACAGGTGTAGCTGGGCCAGATAGCCTAGAGGGGCATCCCGCCGGCACAG
TTTTTATTGGACTGGCACATGCAAAAGGGACAGAGGTGATCAAGGCTAATATCGCAGGACGGAGTCGAGCAGATGTACGT
CACATCGCGGTTATGCATGCCTTTAACCTAGCTCGTAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterProScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.713

100

0.897
  cinA Streptococcus mitis NCTC 12261

89.234

100

0.892
  cinA Streptococcus pneumoniae TIGR4

87.799

100

0.878
  cinA Streptococcus pneumoniae R36A

87.799

100

0.878
  cinA Streptococcus pneumoniae Rx1

87.799

100

0.878
  cinA Streptococcus pneumoniae R6

87.799

100

0.878
  cinA Streptococcus pneumoniae D39

87.56

100

0.876
  cinA Streptococcus mutans UA159

70.096

100

0.701
  cinA Streptococcus suis isolate S10

54.087

99.522

0.538
  cinA Bacillus subtilis subsp. subtilis str. 168

44.976

100

0.45

Multiple sequence alignment