Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   I6L36_RS15180 Genome accession   NZ_CP077378
Coordinates   3204541..3205782 (-) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas sp. FDAARGOS 1406     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3199541..3210782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L36_RS15150 (I6L36_15150) - 3200335..3201519 (+) 1185 WP_109111850.1 tetratricopeptide repeat protein -
  I6L36_RS15155 (I6L36_15155) mutT 3201528..3201932 (+) 405 WP_174213873.1 8-oxo-dGTP diphosphatase MutT -
  I6L36_RS15160 (I6L36_15160) yacG 3201990..3202184 (-) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  I6L36_RS15165 (I6L36_15165) zapD 3202195..3202917 (-) 723 WP_010675825.1 cell division protein ZapD -
  I6L36_RS15170 (I6L36_15170) coaE 3202955..3203569 (-) 615 WP_109111851.1 dephospho-CoA kinase -
  I6L36_RS15175 (I6L36_15175) pilD 3203588..3204463 (-) 876 WP_043154107.1 A24 family peptidase Machinery gene
  I6L36_RS15180 (I6L36_15180) pilC 3204541..3205782 (-) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  I6L36_RS15185 (I6L36_15185) pilB 3205910..3207616 (-) 1707 WP_041213997.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  I6L36_RS15190 (I6L36_15190) - 3207616..3208059 (-) 444 WP_109111852.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  I6L36_RS15195 (I6L36_15195) nadC 3208370..3209233 (-) 864 WP_052814467.1 carboxylating nicotinate-nucleotide diphosphorylase -
  I6L36_RS15200 (I6L36_15200) - 3209237..3209707 (-) 471 WP_104452204.1 TIGR02281 family clan AA aspartic protease -
  I6L36_RS15205 (I6L36_15205) ampD 3209836..3210408 (+) 573 WP_109111853.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=581021 I6L36_RS15180 WP_010675822.1 3204541..3205782(-) (pilC) [Aeromonas sp. FDAARGOS 1406]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=581021 I6L36_RS15180 WP_010675822.1 3204541..3205782(-) (pilC) [Aeromonas sp. FDAARGOS 1406]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACGACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCCGCCGGCGTACCCCTGGTACAGAGCCTGCAGATCATCGCACGCGGCCACGAGAAAGCGGC
GGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACAGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCTC
GCCACTTCGACGACCTCTATTGCGACCTGGTCGAAGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCGATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCGCCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCTGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCACTGGTGGATGCCCTGGTCTCAGCGGCCGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAAGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375