Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   KRG72_RS08240 Genome accession   NZ_CP076703
Coordinates   1662588..1663367 (-) Length   259 a.a.
NCBI ID   WP_258254911.1    Uniprot ID   -
Organism   Streptococcus equinus strain S1     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1657588..1668367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS08225 (KRG72_08235) comE/comE2 1658432..1659166 (-) 735 WP_258254908.1 LytTR family DNA-binding domain-containing protein Regulator
  KRG72_RS08230 (KRG72_08240) comD/comD3 1659827..1661203 (-) 1377 WP_258254909.1 GHKL domain-containing protein Regulator
  KRG72_RS08235 (KRG72_08245) comD/comD3 1661200..1662282 (-) 1083 WP_258254910.1 sensor histidine kinase Regulator
  KRG72_RS08240 comD/comD3 1662588..1663367 (-) 780 WP_258254911.1 sensor histidine kinase Regulator
  KRG72_RS08245 (KRG72_08255) - 1664115..1664408 (-) 294 WP_205395459.1 bacteriocin immunity protein -
  KRG72_RS08250 (KRG72_08260) - 1664436..1664741 (-) 306 WP_133018012.1 bacteriocin immunity protein -
  KRG72_RS08255 (KRG72_08265) - 1664754..1664903 (-) 150 WP_039696228.1 hypothetical protein -
  KRG72_RS08260 (KRG72_08270) - 1665147..1666457 (-) 1311 WP_258254918.1 sensor histidine kinase -
  KRG72_RS08265 (KRG72_08275) comC/comC1 1666772..1666915 (+) 144 WP_160172983.1 hypothetical protein Regulator
  KRG72_RS08270 (KRG72_08280) comD/comD1 1666938..1668260 (-) 1323 WP_074799079.1 sensor histidine kinase Regulator

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 29771.82 Da        Isoelectric Point: 4.6448

>NTDB_id=577482 KRG72_RS08240 WP_258254911.1 1662588..1663367(-) (comD/comD3) [Streptococcus equinus strain S1]
MAKRIHECGSFIYFILLFIFLFYLNFRHGQEQKNELLRNQEMELVALENYSKHVESLYQEVRSFRHDYANVLMSLKMGID
QGNLDDIKKIYEEITADSTKLVKNNKFDLTRLANITDSGVKSLMSAKFLQAENQGIAISLEVAEEMETPKIPLISYIRIL
SILFDNAIEGALESAEPKISVANFYQDGDFVFMIENSTKEKSVDLTKIFERGYSTKGDNRGLGLATLMDFQDDYENLSVE
THSSDCTFTQVVRIYEGER

Nucleotide


Download         Length: 780 bp        

>NTDB_id=577482 KRG72_RS08240 WP_258254911.1 1662588..1663367(-) (comD/comD3) [Streptococcus equinus strain S1]
GTGGCTAAAAGAATTCATGAATGTGGTTCATTTATTTATTTTATTCTTCTCTTTATCTTCCTCTTTTATCTCAATTTCCG
TCATGGGCAAGAGCAGAAAAATGAATTGCTTCGCAATCAAGAGATGGAGCTTGTGGCACTTGAAAATTATAGTAAACACG
TGGAAAGCCTTTATCAGGAGGTTCGCAGCTTTAGGCATGATTACGCCAATGTTTTGATGAGTTTAAAAATGGGGATTGAT
CAAGGCAATCTTGATGACATCAAGAAAATTTACGAGGAAATCACGGCCGATTCGACGAAATTGGTCAAAAATAATAAATT
TGACTTGACTCGTTTGGCTAACATCACAGACAGTGGTGTCAAAAGTCTTATGTCAGCTAAATTCTTGCAGGCGGAAAATC
AAGGAATTGCAATTAGCCTAGAAGTCGCCGAAGAAATGGAAACTCCGAAGATTCCATTGATTTCCTATATTCGAATTTTG
TCGATTCTGTTTGATAATGCCATAGAAGGAGCTTTGGAATCTGCAGAGCCAAAAATCTCAGTTGCTAATTTCTACCAAGA
TGGCGACTTTGTTTTCATGATTGAAAATTCCACTAAGGAAAAATCGGTAGATTTAACTAAGATTTTTGAGCGTGGCTACT
CAACCAAAGGAGACAATCGTGGACTTGGTCTAGCCACACTAATGGATTTCCAAGATGACTACGAAAATCTGTCGGTTGAA
ACCCACAGTTCAGATTGCACATTCACACAAGTAGTGAGAATATATGAGGGAGAGAGGTAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(157-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

90.661

99.228

0.9
  comD/comD2 Streptococcus equinus JB1

91.968

96.139

0.884
  comD/comD1 Streptococcus equinus JB1

48.052

89.189

0.429
  comD/blpH Streptococcus mutans UA159

41.564

93.822

0.39