Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   KRG72_RS08270 Genome accession   NZ_CP076703
Coordinates   1666938..1668260 (-) Length   440 a.a.
NCBI ID   WP_074799079.1    Uniprot ID   A0PCB9
Organism   Streptococcus equinus strain S1     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1661938..1673260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS08240 comD/comD3 1662588..1663367 (-) 780 WP_258254911.1 sensor histidine kinase Regulator
  KRG72_RS08245 (KRG72_08255) - 1664115..1664408 (-) 294 WP_205395459.1 bacteriocin immunity protein -
  KRG72_RS08250 (KRG72_08260) - 1664436..1664741 (-) 306 WP_133018012.1 bacteriocin immunity protein -
  KRG72_RS08255 (KRG72_08265) - 1664754..1664903 (-) 150 WP_039696228.1 hypothetical protein -
  KRG72_RS08260 (KRG72_08270) - 1665147..1666457 (-) 1311 WP_258254918.1 sensor histidine kinase -
  KRG72_RS08265 (KRG72_08275) comC/comC1 1666772..1666915 (+) 144 WP_160172983.1 hypothetical protein Regulator
  KRG72_RS08270 (KRG72_08280) comD/comD1 1666938..1668260 (-) 1323 WP_074799079.1 sensor histidine kinase Regulator
  KRG72_RS08275 (KRG72_08285) comE/comE1 1668265..1668996 (-) 732 WP_258254926.1 response regulator transcription factor Regulator
  KRG72_RS08280 (KRG72_08290) - 1670027..1671319 (-) 1293 WP_258254929.1 glycosyltransferase family 2 protein -
  KRG72_RS08285 (KRG72_08295) - 1671322..1671621 (-) 300 WP_157327346.1 DUF3884 family protein -
  KRG72_RS08290 (KRG72_08300) - 1671647..1671829 (-) 183 WP_157327348.1 hypothetical protein -
  KRG72_RS08295 (KRG72_08305) - 1671895..1672119 (-) 225 WP_039697856.1 helix-turn-helix domain-containing protein -
  KRG72_RS08300 (KRG72_08310) - 1672109..1673107 (-) 999 WP_258254932.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51344.98 Da        Isoelectric Point: 5.7982

>NTDB_id=577484 KRG72_RS08270 WP_074799079.1 1666938..1668260(-) (comD/comD1) [Streptococcus equinus strain S1]
MIKAFLIYFITQLVYYPVIMTIFANVRGEKLNLREIITISLSFFVIDITPFHTIILRILILFLISYLSRKDLPLSLHMFN
GSFPWVIDSIIIRTISFFVLPIFGLDYIDLSENEILFIIVQFSVLAVYFFSIRISKINFQTFIEISEIKSLRKKLVFTDI
TMIFYYTVIEYLTAADFEEKMSTLIYRQWIVFLYFLFFILMLVYMNRSYQNRLEKEIASAREQELRYLSAYSKKVEGLYE
ELRAFRHDYANILVSLKEGIDQDDMGLVRKIYDSVLEDSADFIRNSKFNIGRLVNIDDDAIKSLLSAKFLEAEASNIEVD
LEVKDKIGAPNIPLLDYIRLLAILCDNAIEAALEAKKPAITIACFYQDDDYVLIVDNTTKEESVPVNLIYQKDYSSKGYG
RGIGLTTIHQMMRKYSNLSVQTNSKNYHFSQTIRIKKSFD

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=577484 KRG72_RS08270 WP_074799079.1 1666938..1668260(-) (comD/comD1) [Streptococcus equinus strain S1]
ATGATAAAAGCATTTCTTATTTATTTTATTACGCAACTTGTTTATTATCCTGTTATTATGACAATTTTTGCGAATGTAAG
AGGAGAAAAACTAAACTTACGGGAAATTATAACGATATCTTTGTCGTTTTTTGTTATTGATATTACACCGTTTCACACTA
TCATATTAAGAATCCTAATATTATTTTTAATATCTTATCTTAGTAGAAAAGATTTGCCATTATCTTTGCATATGTTTAAT
GGTAGTTTTCCATGGGTTATTGATAGCATTATTATTAGGACGATTAGTTTTTTTGTTCTACCAATATTCGGGCTAGATTA
TATTGATTTAAGCGAAAATGAAATATTGTTTATCATTGTACAATTTTCAGTGTTAGCGGTTTATTTTTTTAGCATCAGAA
TATCAAAAATCAATTTTCAAACTTTTATTGAGATTAGTGAAATCAAATCTCTGCGTAAAAAATTGGTTTTTACAGATATA
ACAATGATTTTTTATTATACTGTGATTGAATATCTGACTGCAGCAGATTTTGAAGAGAAAATGTCAACTTTAATTTACCG
ACAATGGATAGTTTTTTTATATTTTTTATTTTTTATTCTTATGTTGGTTTATATGAACCGTTCTTATCAAAATAGACTTG
AAAAAGAGATTGCTAGTGCCCGTGAGCAAGAATTAAGATATTTATCAGCTTATAGTAAGAAAGTTGAGGGACTATACGAG
GAGTTACGTGCCTTTCGTCATGATTATGCTAATATCTTAGTCAGCTTAAAAGAGGGAATTGATCAAGATGATATGGGACT
AGTTCGAAAAATCTACGATTCTGTTCTAGAGGATTCGGCGGATTTTATTCGAAATAGCAAATTTAACATTGGGCGCTTGG
TTAATATTGATGACGATGCCATAAAGAGTCTCTTATCTGCTAAGTTTTTAGAAGCAGAAGCAAGTAATATTGAAGTTGAT
TTAGAAGTTAAAGATAAAATAGGAGCGCCAAACATTCCGCTACTAGATTATATTCGTTTGTTGGCTATTTTGTGTGATAA
TGCTATTGAAGCAGCGCTTGAAGCAAAAAAACCAGCCATCACGATTGCTTGTTTTTATCAAGATGATGACTATGTATTAA
TTGTAGATAATACGACCAAGGAAGAGAGTGTTCCAGTTAATTTGATTTATCAAAAAGATTATTCAAGTAAAGGATATGGT
CGAGGTATTGGGCTAACCACGATTCATCAGATGATGCGAAAATATTCCAATCTTTCTGTTCAAACAAATAGTAAAAATTA
CCATTTCAGCCAAACTATTCGTATAAAAAAATCATTCGACTAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(335-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0PCB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

100

52.727

0.527
  comD/comD3 Streptococcus equinus JB1

35.714

100

0.375