Detailed information NTG0577479

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: KRG72_RS08225
• Genome accession: NZ_CP076703
• Coordinates: 1658432..1659166 (-)
• Length: 244 a.a.
• NCBI ID: WP_258254908.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain S1
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1653432..1664166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS08195 (KRG72_08205)	-	1653745..1654683 (-)	939	WP_006531898.1	3'-5' exoribonuclease YhaM family protein	-
KRG72_RS08200 (KRG72_08210)	rmuC	1654673..1655947 (-)	1275	WP_258254898.1	DNA recombination protein RmuC	-
KRG72_RS08205 (KRG72_08215)	-	1655949..1656581 (-)	633	WP_006531896.1	thiamine diphosphokinase	-
KRG72_RS08210 (KRG72_08220)	rpe	1656574..1657236 (-)	663	WP_006531895.1	ribulose-phosphate 3-epimerase	-
KRG72_RS08215 (KRG72_08225)	rsgA	1657243..1658115 (-)	873	WP_006531894.1	ribosome small subunit-dependent GTPase A	-
KRG72_RS08225 (KRG72_08235)	comE/comE2	1658432..1659166 (-)	735	WP_258254908.1	LytTR family DNA-binding domain-containing protein	Regulator
KRG72_RS08230 (KRG72_08240)	comD/comD3	1659827..1661203 (-)	1377	WP_258254909.1	GHKL domain-containing protein	Regulator
KRG72_RS08235 (KRG72_08245)	comD/comD3	1661200..1662282 (-)	1083	WP_258254910.1	sensor histidine kinase	Regulator
KRG72_RS08240	comD/comD3	1662588..1663367 (-)	780	WP_258254911.1	sensor histidine kinase	Regulator

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28867.19 Da
• Isoelectric Point: 6.4989

>NTDB_id=577479 KRG72_RS08225 WP_258254908.1 1658432..1659166(-) (comE/comE2) [Streptococcus equinus strain S1]
MIDIYVLEDNVNQQFRIEKMIGDLLETNQWETRHFDLFSEPDCLTNLVEESFPQIFFLDIDIHGDNTKGIEVAKAIREKS
RTATIVFVTTHSEFMLLTYRAQVSALDFIDKTDKDDAIKDNLKKCLQKVFEDQVFNIPKEIFVFENNKTKIRIPLEDILY
FETAESHRLKLITKTGQRHFYGSIKEVMQANQKLFRCHKSYLINLNNIVRLDKKEGLVYFDDDKACYVSRKYIKDLRSKM
ENLK

Nucleotide

• Length: 735 bp

>NTDB_id=577479 KRG72_RS08225 WP_258254908.1 1658432..1659166(-) (comE/comE2) [Streptococcus equinus strain S1]
ATGATTGATATCTATGTATTAGAAGATAATGTAAATCAGCAGTTCCGTATTGAAAAAATGATTGGAGATTTACTCGAGAC
AAATCAGTGGGAAACTCGTCATTTTGATTTATTTAGTGAACCTGATTGTTTAACTAACCTAGTTGAGGAGTCTTTTCCTC
AAATTTTTTTCCTGGATATTGATATTCATGGAGATAATACCAAAGGAATTGAAGTGGCTAAGGCGATAAGGGAAAAATCA
CGCACAGCGACAATTGTTTTTGTGACGACTCACTCTGAATTCATGTTATTAACTTATCGAGCGCAAGTTAGTGCACTTGA
TTTTATTGATAAAACAGATAAAGATGATGCGATAAAAGATAACTTAAAAAAATGCTTGCAAAAGGTCTTTGAGGACCAAG
TTTTTAACATTCCTAAGGAAATATTTGTTTTTGAAAATAACAAAACGAAAATCCGCATTCCCTTGGAAGATATCCTTTAT
TTTGAAACCGCGGAAAGTCATCGCCTGAAGTTGATTACAAAAACTGGGCAACGTCATTTTTATGGTTCAATCAAAGAAGT
GATGCAAGCTAATCAGAAATTATTTAGATGTCATAAATCATATCTGATTAATCTAAATAATATTGTTAGGTTAGATAAAA
AAGAAGGTTTGGTTTATTTTGACGATGATAAAGCCTGTTATGTTTCTAGAAAATATATCAAAGACTTAAGGTCAAAAATG
GAAAATCTGAAATAG

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (19-120)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus equinus JB1	99.59	100	0.996
comE/comE1	Streptococcus equinus JB1	45.041	99.18	0.447
comE/blpR	Streptococcus mutans UA159	40.664	98.77	0.402
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	36.145	100	0.369
comE/comE2	Streptococcus gordonii strain NCTC7865	36.145	100	0.369
comE	Streptococcus pneumoniae R6	35.039	100	0.365
comE	Streptococcus pneumoniae TIGR4	35.039	100	0.365
comE	Streptococcus mitis SK321	35.039	100	0.365
comE	Streptococcus mitis NCTC 12261	35.039	100	0.365
comE	Streptococcus pneumoniae Rx1	35.039	100	0.365
comE	Streptococcus pneumoniae D39	35.039	100	0.365