Detailed information NTG0568798

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: ML603_RS08940
• Genome accession: NZ_CP092887
• Coordinates: 1804564..1805304 (-)
• Length: 246 a.a.
• NCBI ID: WP_192942416.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain Karl
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1799564..1810304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ML603_RS08915 (ML603_08915)	-	1800449..1801162 (-)	714	WP_241067166.1	N-acetylmannosamine-6-phosphate 2-epimerase	-
ML603_RS08920 (ML603_08920)	rpmH	1801493..1801627 (-)	135	WP_002885866.1	50S ribosomal protein L34	-
ML603_RS08925 (ML603_08925)	jag	1801942..1802856 (-)	915	WP_129556293.1	RNA-binding cell elongation regulator Jag/EloR	-
ML603_RS08930 (ML603_08930)	-	1802868..1803695 (-)	828	WP_111679436.1	YidC/Oxa1 family membrane protein insertase	-
ML603_RS08935 (ML603_08935)	rnpA	1803661..1804020 (-)	360	WP_003056083.1	ribonuclease P protein component	-
ML603_RS08940 (ML603_08940)	comE/blpR	1804564..1805304 (-)	741	WP_192942416.1	LytTR family DNA-binding domain-containing protein	Regulator
ML603_RS08945 (ML603_08945)	-	1805308..1806591 (-)	1284	WP_241067168.1	sensor histidine kinase	-
ML603_RS08950 (ML603_08950)	-	1806592..1807935 (-)	1344	WP_241067169.1	GHKL domain-containing protein	-
ML603_RS08955 (ML603_08955)	gltX	1808262..1809710 (-)	1449	WP_143927968.1	glutamate--tRNA ligase	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28978.27 Da
• Isoelectric Point: 4.7908

>NTDB_id=568798 ML603_RS08940 WP_192942416.1 1804564..1805304(-) (comE/blpR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MMNIFILEDDFIQQTRIESVVADILEEAKIPCNQLEVFANPHKLFESIQERGDHQLYFLDIEIGDEDRRGLELAADIRQK
DPNAVIVFVTTHSEFAPISFKYKVSALDFIDKAVDKEQFRDQIEECIRYTYEMMSSRESEDMFLFETPQTRLKLPYKDIL
YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQLLYFDNGDSCMVSRLKMKCLFE
KWEALH

Nucleotide

• Length: 741 bp

>NTDB_id=568798 ML603_RS08940 WP_192942416.1 1804564..1805304(-) (comE/blpR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGATGAATATTTTTATTCTTGAAGATGATTTTATCCAACAGACACGTATTGAATCTGTAGTGGCAGACATCTTGGAAGA
AGCTAAAATCCCTTGTAATCAGCTAGAAGTGTTTGCCAATCCTCATAAATTATTTGAAAGCATTCAAGAAAGAGGCGATC
ACCAGCTATATTTTTTAGACATTGAGATTGGTGATGAGGATCGCCGAGGGCTTGAATTGGCAGCAGATATTCGACAAAAA
GACCCCAATGCGGTCATTGTGTTTGTTACAACACATTCTGAATTTGCTCCTATTTCTTTTAAATACAAAGTGTCTGCCTT
AGATTTTATTGACAAAGCAGTTGATAAGGAACAATTCAGGGATCAGATTGAAGAATGTATCCGCTATACCTATGAGATGA
TGTCTAGCCGAGAATCAGAAGACATGTTTCTATTTGAGACCCCTCAGACAAGATTGAAATTACCTTACAAAGATATCCTT
TATTTTGCTACTGCTACGACACCCCACAAGGTGTGTTTGTGGACTCAGACGGAGAGACTGGAGTTTTATGGCAATTTATC
TGAGATACAAGCTGTGGCTCCAAAGCTTTTCTTATGCCATAGATCTTACTTGGTTAATCTAGATAAGGTTGTGCGTATTG
ATAAATCCAAACAACTCCTCTATTTTGATAATGGGGATTCCTGCATGGTCTCACGCTTAAAAATGAAATGCCTTTTTGAA
AAATGGGAAGCCTTACATTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.117	97.154	0.467
comE/comE1	Streptococcus equinus JB1	42.857	96.748	0.415
comE/comE2	Streptococcus equinus JB1	40.408	99.593	0.402
comE/comE2	Streptococcus gordonii strain NCTC7865	39.113	100	0.394
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	39.113	100	0.394
comE	Streptococcus mitis NCTC 12261	36.929	97.967	0.362
comE	Streptococcus pneumoniae Rx1	36.929	97.967	0.362
comE	Streptococcus pneumoniae D39	36.929	97.967	0.362
comE	Streptococcus pneumoniae R6	36.929	97.967	0.362
comE	Streptococcus pneumoniae TIGR4	36.929	97.967	0.362
comE	Streptococcus mitis SK321	36.929	97.967	0.362