Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   KEM15_RS00415 Genome accession   NZ_CP073632
Coordinates   71612..72793 (+) Length   393 a.a.
NCBI ID   WP_217374496.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NN1     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 66612..77793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KEM15_RS00400 (KEM15_00385) mutL 67613..69550 (+) 1938 WP_274504899.1 DNA mismatch repair endonuclease MutL -
  KEM15_RS00405 (KEM15_00390) ruvA 69796..70386 (+) 591 WP_274504434.1 Holliday junction branch migration protein RuvA -
  KEM15_RS00410 (KEM15_00395) - 71006..71575 (+) 570 WP_274504435.1 DNA-3-methyladenine glycosylase I -
  KEM15_RS00415 (KEM15_00400) cinA 71612..72793 (+) 1182 WP_217374496.1 competence/damage-inducible protein A Machinery gene
  KEM15_RS00420 (KEM15_00405) recA 72845..73999 (+) 1155 WP_172036461.1 recombinase RecA Machinery gene
  KEM15_RS00425 (KEM15_00410) spx 74213..74611 (+) 399 WP_217374497.1 transcriptional regulator Spx -
  KEM15_RS00430 (KEM15_00415) - 74721..74987 (+) 267 WP_130554425.1 IreB family regulatory phosphoprotein -
  KEM15_RS00435 (KEM15_00420) ruvX 74987..75406 (+) 420 WP_130554426.1 Holliday junction resolvase RuvX -
  KEM15_RS00440 (KEM15_00425) - 75418..75738 (+) 321 WP_024392832.1 DUF1292 domain-containing protein -
  KEM15_RS00445 (KEM15_00430) - 75938..76078 (+) 141 Protein_67 ISL3 family transposase -
  KEM15_RS00450 (KEM15_00435) - 76108..76657 (+) 550 Protein_68 nucleotidyltransferase family protein -
  KEM15_RS00455 (KEM15_00440) comX/sigX 76840..77310 (+) 471 WP_130554428.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42726.70 Da        Isoelectric Point: 4.4569

>NTDB_id=559493 KEM15_RS00415 WP_217374496.1 71612..72793(+) (cinA) [Streptococcus parasuis strain NN1]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSDLVILCGGLGPTEDDLTKQT
LATFLQKELVVDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPFLTQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTIAPYAKVGEVTLRLSTKADSQEEANVRLNQLEEE
ILQRDHLRVFFYAYGDDNSLVKTVATLLEEKKQSLGILENGTGGLLQAELSLALAGQPYYSGGKIIGQLGTESGGLSEEA
SRIREELQADLGLVVSVAVKPESTVDNVLAKVYLALASTSGISKKEVDLGGYSWQYLRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=559493 KEM15_RS00415 WP_217374496.1 71612..72793(+) (cinA) [Streptococcus parasuis strain NN1]
ATGAAAGCAGAATTAATTGCTGTTGGAACAGAAATATTGACAGGTCAAATTGTGAATACGAATGCTCAATTCTTGTCAGA
AAAATGTGCAGAGCTAGGTATCGATGTATACTTCCACACTGCTGTAGGTGATAATGAACAGCGACTATTGTCTGTACTTG
AAATTGCAAGTAAACGAAGTGATCTGGTCATTTTATGTGGTGGTTTAGGTCCTACTGAAGACGACTTGACCAAGCAAACT
TTAGCGACATTTTTGCAAAAAGAGTTGGTTGTTGACGAACTAGCGATGGCAAAATTAGACCGTTTTTTTGCCAGTCGACC
AGGTCGTGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAACCCAGCTGGTT
TAGCTGTAGGTGGTATGATTGAGCAAGATGGTGTGACCTATATTGTTTTGCCTGGCCCACCAAGTGAACTCAAGGCCATG
TTTTCTGAGAGTCTGTTACCTTTTTTGACTCAATCTCAGCAACAACTTTACTCGCGTGTCCTACGCTTTTTTGGAATAGG
TGAAAGCCAGTTGGTGACTGTTTTAGCGGATTTGATTGACAAGCAGACAGACCCGACTATTGCGCCTTATGCAAAAGTTG
GAGAGGTGACGCTTCGTTTGTCTACGAAGGCAGATAGCCAGGAAGAAGCGAACGTGCGTTTGAATCAGTTGGAAGAAGAG
ATATTGCAACGTGACCATTTGAGAGTTTTTTTCTATGCATATGGGGATGACAATAGTTTGGTTAAAACCGTAGCGACTCT
TTTAGAGGAAAAGAAACAATCTTTGGGCATCCTAGAGAATGGAACAGGTGGTTTATTACAAGCAGAATTGAGTCTGGCTT
TGGCTGGTCAGCCGTATTATAGTGGAGGAAAAATCATCGGTCAGCTAGGGACAGAATCGGGCGGGCTATCAGAAGAAGCA
AGTCGCATTCGGGAGGAACTACAAGCTGATTTAGGGCTAGTTGTGTCGGTGGCAGTCAAACCAGAATCAACAGTAGACAA
CGTACTTGCTAAAGTATATCTAGCCTTGGCCAGTACCTCGGGTATTTCTAAAAAAGAGGTAGATTTAGGAGGTTATTCAT
GGCAATACCTTCGTCAACTTGCTTGTTTACAGGCGTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

87.023

100

0.87
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

55.048

100

0.583
  cinA Streptococcus pneumoniae TIGR4

54.808

100

0.58
  cinA Streptococcus pneumoniae Rx1

54.808

100

0.58
  cinA Streptococcus pneumoniae R6

54.808

100

0.58
  cinA Streptococcus mutans UA159

55.474

100

0.58
  cinA Streptococcus pneumoniae D39

54.567

100

0.578
  cinA Bacillus subtilis subsp. subtilis str. 168

47.869

77.608

0.372