Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   J4854_RS09960 Genome accession   NZ_CP072329
Coordinates   2064322..2065590 (-) Length   422 a.a.
NCBI ID   WP_200772396.1    Uniprot ID   -
Organism   Streptococcus lactarius strain CCUG 66490     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2059322..2070590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS09930 (J4854_09930) - 2060709..2061014 (-) 306 WP_003001941.1 DUF1292 domain-containing protein -
  J4854_RS09935 (J4854_09935) ruvX 2061037..2061456 (-) 420 WP_200772399.1 Holliday junction resolvase RuvX -
  J4854_RS09940 (J4854_09940) - 2061456..2061722 (-) 267 WP_003002070.1 IreB family regulatory phosphoprotein -
  J4854_RS09945 (J4854_09945) - 2061837..2062433 (-) 597 WP_200772398.1 SP0191 family lipoprotein -
  J4854_RS09950 (J4854_09950) spx 2062571..2062969 (-) 399 WP_003009108.1 transcriptional regulator Spx -
  J4854_RS09955 (J4854_09955) recA 2063057..2064202 (-) 1146 WP_200772397.1 recombinase RecA Machinery gene
  J4854_RS09960 (J4854_09960) cinA 2064322..2065590 (-) 1269 WP_200772396.1 competence/damage-inducible protein A Machinery gene
  J4854_RS09965 (J4854_09965) - 2065947..2066978 (+) 1032 WP_200772395.1 S66 family peptidase -
  J4854_RS09970 (J4854_09970) - 2067194..2067760 (-) 567 WP_200772394.1 DNA-3-methyladenine glycosylase I -
  J4854_RS09975 (J4854_09975) ruvA 2067770..2068363 (-) 594 WP_200772393.1 Holliday junction branch migration protein RuvA -
  J4854_RS09980 (J4854_09980) mutL 2068384..2070327 (-) 1944 WP_200772392.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45144.27 Da        Isoelectric Point: 4.5571

>NTDB_id=552069 J4854_RS09960 WP_200772396.1 2064322..2065590(-) (cinA) [Streptococcus lactarius strain CCUG 66490]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYYHVAVGDNEGRLLATIETASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGEELVFDPTALAKLDTFFASRPDYVRTPNNERQAQMIAGSIPLQNRTGLAVGGLIEVDGVTYVVLPGPPSELKPM
VNEQLVPHLTTGEQLFSRVLRFFGIGESQLVTILADIIEEQSDPTVAPYAKTGEVTLRLSTKAKDQAEAEAKLDVLEKEI
LSRHTLDHQPLQELFYGYGDDNSMAKVAFDLLKQTGKTITAAESLTAGLFQATLADFSGASSIFAGGFVTYSLEEKSKML
SIPAQELEQHGVVSHFTAQAMASQARKLTGSDYGVSLTGVAGPDSLEEHPAGTVFIGLATPSGVDSVQVNIAGRSRADVR
EIAVLHAFNLVRLAVLNGENLV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=552069 J4854_RS09960 WP_200772396.1 2064322..2065590(-) (cinA) [Streptococcus lactarius strain CCUG 66490]
ATGAAGGCGGAAATTATTGCAGTTGGAACAGAAATTCTAACAGGACAAATTGTCAATACCAATGCCCAATTCTTGTCTGA
GAAATTAGCTAGTTTAGGGATTGATGTCTATTATCATGTGGCGGTAGGAGACAACGAAGGTCGTCTTTTAGCCACTATTG
AAACAGCTTCAAAACGCAGCGATTTGGTGATTTTATGCGGTGGACTTGGTCCAACAGAGGATGATTTGACCAAGCAAACC
CTTGCTAAGTTTTTAGGGGAAGAACTGGTTTTTGATCCGACAGCACTTGCCAAACTCGACACCTTCTTTGCCAGTCGCCC
AGATTATGTCCGGACACCCAATAATGAGCGACAAGCACAAATGATCGCCGGATCAATCCCCCTTCAAAACCGTACAGGTC
TCGCGGTTGGAGGTTTGATTGAAGTCGACGGAGTGACCTATGTCGTTCTACCTGGTCCACCAAGTGAATTAAAACCAATG
GTCAATGAACAATTGGTGCCTCATTTAACAACAGGGGAGCAGCTCTTTTCTAGAGTTTTGCGCTTCTTTGGGATTGGGGA
AAGCCAGCTAGTTACGATCCTAGCCGATATCATTGAAGAACAGAGTGATCCAACAGTGGCTCCTTATGCCAAGACGGGAG
AAGTGACCTTGCGTCTGTCTACAAAGGCGAAAGATCAGGCAGAAGCGGAAGCTAAGCTCGATGTCTTAGAAAAGGAGATC
TTATCACGCCACACTCTGGATCATCAACCCTTGCAAGAGTTGTTTTACGGTTATGGAGATGACAATTCGATGGCCAAGGT
TGCCTTTGATCTCTTGAAACAGACTGGAAAGACTATTACAGCTGCAGAAAGCCTGACGGCTGGCCTCTTCCAAGCAACTC
TGGCAGATTTTTCAGGGGCGTCCAGCATCTTCGCGGGTGGTTTTGTCACCTATAGTTTGGAAGAAAAAAGTAAGATGTTG
TCTATTCCAGCTCAAGAGTTGGAGCAACATGGAGTGGTGTCTCATTTTACAGCCCAAGCCATGGCGTCACAGGCCCGTAA
GTTAACAGGATCCGATTATGGTGTTAGCCTGACCGGAGTTGCGGGACCAGATAGCCTAGAAGAGCATCCGGCAGGGACCG
TCTTTATCGGACTTGCGACTCCAAGTGGAGTGGATAGTGTCCAAGTCAATATCGCCGGACGTAGCCGGGCGGATGTCCGC
GAAATTGCAGTCCTTCATGCCTTTAATTTGGTGCGCTTGGCTGTATTAAATGGTGAAAATTTGGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-412)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.58

98.815

0.737
  cinA Streptococcus mitis NCTC 12261

74.341

98.815

0.735
  cinA Streptococcus pneumoniae TIGR4

73.381

98.815

0.725
  cinA Streptococcus pneumoniae Rx1

73.381

98.815

0.725
  cinA Streptococcus pneumoniae R6

73.381

98.815

0.725
  cinA Streptococcus pneumoniae D39

73.141

98.815

0.723
  cinA Streptococcus mutans UA159

70.449

100

0.706
  cinA Streptococcus suis isolate S10

56.174

97.867

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

47.101

98.104

0.462