Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   J5M87_RS09435 Genome accession   NZ_CP072115
Coordinates   2017237..2018439 (-) Length   400 a.a.
NCBI ID   WP_154607602.1    Uniprot ID   A0A6I4R7P3
Organism   Streptococcus zhangguiae strain zg-86     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2012237..2023439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS09405 (J5M87_09405) - 2012867..2013796 (-) 930 WP_154607597.1 XRE family transcriptional regulator -
  J5M87_RS09410 (J5M87_09410) - 2014180..2014491 (-) 312 WP_154607598.1 DUF1292 domain-containing protein -
  J5M87_RS09415 (J5M87_09415) ruvX 2014502..2014921 (-) 420 WP_154607599.1 Holliday junction resolvase RuvX -
  J5M87_RS09420 (J5M87_09420) - 2014921..2015187 (-) 267 WP_075099514.1 IreB family regulatory phosphoprotein -
  J5M87_RS09425 (J5M87_09425) spx 2015362..2015760 (-) 399 WP_154607600.1 transcriptional regulator Spx -
  J5M87_RS09430 (J5M87_09430) recA 2016036..2017202 (-) 1167 WP_154607601.1 recombinase RecA Machinery gene
  J5M87_RS09435 (J5M87_09435) cinA 2017237..2018439 (-) 1203 WP_154607602.1 competence/damage-inducible protein A Machinery gene
  J5M87_RS09440 (J5M87_09440) - 2018513..2019184 (-) 672 WP_154607603.1 CPBP family intramembrane glutamic endopeptidase -
  J5M87_RS09445 (J5M87_09445) - 2019157..2019558 (-) 402 WP_202120285.1 helix-turn-helix transcriptional regulator -
  J5M87_RS09450 (J5M87_09450) - 2019645..2020232 (-) 588 WP_154607604.1 GNAT family N-acetyltransferase -
  J5M87_RS09455 (J5M87_09455) - 2020225..2020791 (-) 567 WP_154607605.1 DNA-3-methyladenine glycosylase I -
  J5M87_RS09460 (J5M87_09460) ruvA 2020803..2021393 (-) 591 WP_154607606.1 Holliday junction branch migration protein RuvA -
  J5M87_RS09465 (J5M87_09465) mutL 2021407..2023335 (-) 1929 WP_154607607.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 43374.98 Da        Isoelectric Point: 5.5262

>NTDB_id=550560 J5M87_RS09435 WP_154607602.1 2017237..2018439(-) (cinA) [Streptococcus zhangguiae strain zg-86]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVFFHTAVGDNEKRLLSVLDVASRRSELVVLCGGLGPTEDDLTKQT
LAKFLGRNLVSDKTALAKLDRFFASRKGRVRTANNERQAQLVEGSIALQNPAGLAVGGLIEQGGVTYAVLPGPPSELKAM
FTESLQPLLMHSNEKLYSRVLRFFGIGESQLVTILEDLIASQSDPTLAPYAKTGEVTLRLSTKADNIILANEKLDQLEKE
ILARENLASCLYGYGDDNSLDRIVADELEKQQITFAIAENVTAGLLQSDLTIALQGRQLFKGGVVVSDSTCNGAKAEELA
KSICKNSGAILGMALLGTINPESQIDNVLARFYIAICFDNRVIVSEVELGGYTEKHMRQIACLHALSAMRKILLKHKNLL

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=550560 J5M87_RS09435 WP_154607602.1 2017237..2018439(-) (cinA) [Streptococcus zhangguiae strain zg-86]
ATGAAAGCAGAGTTGATTGCGGTAGGTACCGAGATTCTGACTGGGCAAATCGTCAATACAAATGCGCAATTTTTATCAGA
AAAATGTGCAGAATTAGGTATTGATGTCTTTTTTCATACAGCAGTTGGTGATAATGAAAAACGGCTCTTATCTGTTCTAG
ATGTGGCGAGTAGGAGAAGCGAGTTAGTCGTTCTTTGTGGCGGACTAGGGCCTACTGAAGATGACTTGACCAAGCAGACA
TTGGCTAAATTTTTAGGTCGAAATCTAGTCTCTGATAAAACTGCTTTGGCAAAGTTAGACCGTTTTTTTGCAAGTAGAAA
AGGTCGTGTTCGGACAGCGAATAACGAGCGGCAAGCTCAGTTGGTAGAAGGTAGTATTGCACTTCAAAATCCAGCAGGTT
TAGCGGTTGGCGGCTTAATAGAACAGGGTGGCGTGACCTATGCTGTATTGCCTGGCCCCCCAAGTGAGTTAAAGGCCATG
TTTACAGAAAGTTTACAGCCTTTATTGATGCATTCCAATGAAAAGCTATACTCTCGTGTATTGCGCTTTTTTGGTATCGG
TGAAAGTCAGCTAGTGACTATTTTAGAGGATTTGATTGCTTCTCAGTCTGATCCGACCCTAGCTCCATACGCCAAGACAG
GAGAGGTTACCCTACGCCTATCTACGAAAGCAGACAACATTATTCTAGCCAATGAAAAACTAGATCAATTGGAAAAAGAG
ATTCTTGCACGAGAAAATCTTGCATCTTGCCTTTATGGGTACGGAGACGACAACAGTCTAGATAGGATTGTAGCTGATGA
ATTGGAAAAACAACAAATTACCTTCGCCATTGCTGAAAATGTAACAGCAGGCTTGCTTCAGTCTGACTTGACAATTGCTT
TACAGGGTCGTCAACTGTTTAAAGGTGGTGTTGTGGTATCAGATTCAACCTGTAATGGTGCAAAAGCAGAAGAGTTGGCA
AAAAGCATCTGTAAAAACTCAGGAGCTATTCTAGGCATGGCGCTACTTGGCACTATAAATCCTGAATCGCAAATTGATAA
TGTTCTAGCACGCTTTTACATTGCAATTTGTTTCGATAATCGTGTGATAGTGTCAGAGGTTGAACTAGGTGGCTATACTG
AAAAACATATGCGACAAATTGCTTGTTTGCATGCTTTGAGTGCTATGCGTAAGATTTTGTTAAAGCATAAAAATTTGCTA
TAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-252)

Competence-damaged protein (CinA)

(258-306)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-171)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4R7P3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

65.394

98.25

0.642
  cinA Streptococcus mutans UA159

55.263

100

0.577
  cinA Streptococcus mitis SK321

54.676

100

0.57
  cinA Streptococcus mitis NCTC 12261

54.676

100

0.57
  cinA Streptococcus pneumoniae TIGR4

53.957

100

0.563
  cinA Streptococcus pneumoniae Rx1

53.717

100

0.56
  cinA Streptococcus pneumoniae R6

53.717

100

0.56
  cinA Streptococcus pneumoniae D39

53.477

100

0.557
  cinA Bacillus subtilis subsp. subtilis str. 168

43.478

97.75

0.425