Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   J5Z97_RS00665 Genome accession   NZ_CP072112
Coordinates   103006..103944 (+) Length   312 a.a.
NCBI ID   WP_023611500.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M08500     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98006..108944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS00655 (J5Z97_00655) rpoC 98755..102396 (+) 3642 WP_023611494.1 DNA-directed RNA polymerase subunit beta' -
  J5Z97_RS00660 (J5Z97_00660) - 102548..102913 (+) 366 WP_002986560.1 DUF1033 family protein -
  J5Z97_RS00665 (J5Z97_00665) comYA 103006..103944 (+) 939 WP_023611500.1 competence type IV pilus ATPase ComGA Machinery gene
  J5Z97_RS00670 (J5Z97_00670) comYB 103880..104914 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  J5Z97_RS00675 (J5Z97_00675) comYC 104916..105242 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  J5Z97_RS00680 (J5Z97_00680) comGD 105217..105645 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  J5Z97_RS00685 (J5Z97_00685) comGE 105602..105886 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  J5Z97_RS00690 (J5Z97_00690) comYF 105879..106313 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  J5Z97_RS00695 (J5Z97_00695) comGG 106297..106623 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  J5Z97_RS00700 (J5Z97_00700) comYH 106721..107674 (+) 954 WP_023611497.1 class I SAM-dependent methyltransferase Machinery gene
  J5Z97_RS00705 (J5Z97_00705) - 107733..108929 (+) 1197 WP_208769276.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35060.33 Da        Isoelectric Point: 8.8689

>NTDB_id=550453 J5Z97_RS00665 WP_023611500.1 103006..103944(+) (comYA) [Streptococcus pyogenes strain M08500]
MVQALAKAILAKAERVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=550453 J5Z97_RS00665 WP_023611500.1 103006..103944(+) (comYA) [Streptococcus pyogenes strain M08500]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACGGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.415

99.679

0.612
  comYA Streptococcus mutans UA159

61.415

99.679

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.679

0.606
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.645

99.359

0.603
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.679

0.596
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.679

0.59
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369