Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   J5Z97_RS00700 Genome accession   NZ_CP072112
Coordinates   106721..107674 (+) Length   317 a.a.
NCBI ID   WP_023611497.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M08500     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 101721..112674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS00660 (J5Z97_00660) - 102548..102913 (+) 366 WP_002986560.1 DUF1033 family protein -
  J5Z97_RS00665 (J5Z97_00665) comYA 103006..103944 (+) 939 WP_023611500.1 competence type IV pilus ATPase ComGA Machinery gene
  J5Z97_RS00670 (J5Z97_00670) comYB 103880..104914 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  J5Z97_RS00675 (J5Z97_00675) comYC 104916..105242 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  J5Z97_RS00680 (J5Z97_00680) comGD 105217..105645 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  J5Z97_RS00685 (J5Z97_00685) comGE 105602..105886 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  J5Z97_RS00690 (J5Z97_00690) comYF 105879..106313 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  J5Z97_RS00695 (J5Z97_00695) comGG 106297..106623 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  J5Z97_RS00700 (J5Z97_00700) comYH 106721..107674 (+) 954 WP_023611497.1 class I SAM-dependent methyltransferase Machinery gene
  J5Z97_RS00705 (J5Z97_00705) - 107733..108929 (+) 1197 WP_208769276.1 acetate kinase -
  J5Z97_RS00710 (J5Z97_00710) - 109116..109425 (+) 310 Protein_89 hypothetical protein -
  J5Z97_RS00715 (J5Z97_00715) proC 109508..110278 (-) 771 WP_023611530.1 pyrroline-5-carboxylate reductase -
  J5Z97_RS00720 (J5Z97_00720) pepA 110326..111393 (-) 1068 WP_023611498.1 glutamyl aminopeptidase -
  J5Z97_RS00725 (J5Z97_00725) - 111858..112139 (+) 282 WP_023611512.1 DUF4651 domain-containing protein -
  J5Z97_RS00730 (J5Z97_00730) - 112139..112456 (+) 318 WP_002987805.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35989.02 Da        Isoelectric Point: 4.7205

>NTDB_id=550457 J5Z97_RS00700 WP_023611497.1 106721..107674(+) (comYH) [Streptococcus pyogenes strain M08500]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFSKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=550457 J5Z97_RS00700 WP_023611497.1 106721..107674(+) (comYH) [Streptococcus pyogenes strain M08500]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGTGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTAGTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

65.506

99.685

0.653
  comYH Streptococcus mutans UA140

65.19

99.685

0.65