Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   SPYOHK_RS08585 Genome accession   NZ_AFRY01000001
Coordinates   104337..104621 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes HKU QMH11M0907901     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 99337..109621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYOHK_RS08610 (SPYOHK_00410) - 101283..101648 (+) 366 WP_002986560.1 DUF1033 family protein -
  SPYOHK_RS08605 (SPYOHK_00415) comGA 101741..102679 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  SPYOHK_RS08600 (SPYOHK_00420) comGB 102615..103649 (+) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPYOHK_RS08595 (SPYOHK_00425) comGC 103651..103977 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  SPYOHK_RS08590 (SPYOHK_00430) comGD 103952..104380 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPYOHK_RS08585 (SPYOHK_00435) comGE 104337..104621 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPYOHK_RS08580 (SPYOHK_00440) comGF 104614..105048 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPYOHK_RS08575 (SPYOHK_00445) comGG 105032..105358 (+) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  SPYOHK_RS08570 (SPYOHK_00450) comGH 105456..106409 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  SPYOHK_RS08565 (SPYOHK_00455) - 106468..107664 (+) 1197 WP_002987791.1 acetate kinase -
  SPYOHK_RS08560 (SPYOHK_00460) - 107851..108159 (+) 309 WP_002987795.1 hypothetical protein -
  SPYOHK_RS08555 (SPYOHK_00465) proC 108242..109012 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence


Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=53984 SPYOHK_RS08585 WP_002987779.1 104337..104621(+) (comGE) [Streptococcus pyogenes HKU QMH11M0907901]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=53984 SPYOHK_RS08585 WP_002987779.1 104337..104621(+) (comGE) [Streptococcus pyogenes HKU QMH11M0907901]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATTGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383


Multiple sequence alignment