Detailed information NTG0526817

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: I6J12_RS09740
• Genome accession: NZ_CP068060
• Coordinates: 2029062..2029811 (-)
• Length: 249 a.a.
• NCBI ID: WP_003038257.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain FDAARGOS_1155
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2024062..2034811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J12_RS09720 (I6J12_09720)	-	2024443..2026065 (+)	1623	WP_003038260.1	ATP-binding cassette domain-containing protein	-
I6J12_RS09725 (I6J12_09725)	-	2026139..2028715 (+)	2577	WP_004225037.1	YfhO family protein	-
I6J12_RS09740 (I6J12_09740)	comE/comE2	2029062..2029811 (-)	750	WP_003038257.1	competence system response regulator transcription factor ComE	Regulator
I6J12_RS09745 (I6J12_09745)	comD/comD2	2029811..2031133 (-)	1323	WP_003038254.1	GHKL domain-containing protein	Regulator
I6J12_RS09750 (I6J12_09750)	-	2031148..2031297 (-)	150	WP_003038250.1	bacteriocin	-
I6J12_RS09760 (I6J12_09760)	rlmH	2031579..2032058 (-)	480	WP_004225060.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
I6J12_RS09765 (I6J12_09765)	htrA	2032252..2033442 (+)	1191	WP_003032033.1	S1C family serine protease	Regulator
I6J12_RS09770 (I6J12_09770)	spo0J	2033497..2034264 (+)	768	WP_003038259.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29216.88 Da
• Isoelectric Point: 8.6042

>NTDB_id=526817 I6J12_RS09740 WP_003038257.1 2029062..2029811(-) (comE/comE2) [Streptococcus anginosus strain FDAARGOS_1155]
MKVLVLEDEITHQVRMETTLAEIAKEMGITIKVKVTGKVREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFIRHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLSDVAFKKHIKDSIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETRRFFSPHKSYLVNIGNIKGYDKKMREIIFYEDHRCPITRMKLGKL
KAILEELKG

Nucleotide

• Length: 750 bp

>NTDB_id=526817 I6J12_RS09740 WP_003038257.1 2029062..2029811(-) (comE/comE2) [Streptococcus anginosus strain FDAARGOS_1155]
ATGAAAGTATTAGTATTAGAAGATGAAATTACACATCAAGTAAGAATGGAAACAACTTTGGCAGAGATTGCAAAAGAAAT
GGGAATTACGATAAAAGTTAAAGTAACTGGAAAAGTAAGGGAATTTAAAGAATATATTGAAAACGATGAAGTAAATCAAT
TATATTTTTTAGATATTGATATTAAAGGAGAGGAAACAAAAGGTTTAGAAATAGCAAAATTTATACGTCATCACAATCCG
TATGCCATTATTGTTTTTGTTACAACGAAATCAGAATTTGCCACTATGACCTTCAAATATAAGGTATCTGCACTGGATTT
TGTTGATAAAAATTTGAGTGATGTTGCTTTTAAAAAACATATAAAAGACAGCATTGAGTATACAAAAGCGACATTGATTG
AAAATAAAGATATGGTGGATTATTTTGAATATAGCTTTCGTGGCGGAGAGGTTAGAATGCCTTTTAATGACATTTTATAT
ATTGAAACGACAGGCTCTTCTCATAAATTAAGAATTGTCGGTAAAAACTTTTTTAAAGAATTCTATGGCACTATTGCAGA
TATTCAAGAAAAAGATAAAGAAACAAGACGTTTCTTTTCACCTCATAAATCCTACCTAGTCAATATTGGAAACATCAAAG
GTTATGACAAAAAAATGCGAGAAATAATTTTTTATGAAGATCATCGTTGTCCGATTACTCGAATGAAACTTGGAAAATTA
AAAGCTATTTTAGAGGAATTAAAAGGATAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-244)

• Response regulator receiver domain (Response_reg) (3-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus gordonii strain NCTC7865	70.492	97.992	0.691
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	70.492	97.992	0.691
comE	Streptococcus mitis NCTC 12261	70.204	98.394	0.691
comE	Streptococcus infantis strain Atu-4	69.796	98.394	0.687
comE	Streptococcus mitis SK321	69.388	98.394	0.683
comE	Streptococcus pneumoniae Rx1	68.98	98.394	0.679
comE	Streptococcus pneumoniae D39	68.98	98.394	0.679
comE	Streptococcus pneumoniae R6	68.98	98.394	0.679
comE	Streptococcus pneumoniae TIGR4	68.98	98.394	0.679
comE/blpR	Streptococcus mutans UA159	40.891	99.197	0.406