Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I6J14_RS08580 Genome accession   NZ_CP068057
Coordinates   1693192..1694463 (+) Length   423 a.a.
NCBI ID   WP_115253190.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1688192..1699463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS08555 (I6J14_08555) mutL 1688322..1690304 (+) 1983 WP_115253272.1 DNA mismatch repair endonuclease MutL -
  I6J14_RS08560 (I6J14_08560) - 1690315..1691535 (+) 1221 WP_115253194.1 MFS transporter -
  I6J14_RS08565 (I6J14_08565) ruvA 1691537..1692130 (+) 594 WP_115253193.1 Holliday junction branch migration protein RuvA -
  I6J14_RS08570 (I6J14_08570) - 1692140..1692712 (+) 573 WP_115253192.1 DNA-3-methyladenine glycosylase I -
  I6J14_RS08575 (I6J14_08575) - 1692715..1693068 (+) 354 WP_115253191.1 VOC family protein -
  I6J14_RS08580 (I6J14_08580) cinA 1693192..1694463 (+) 1272 WP_115253190.1 competence/damage-inducible protein A Machinery gene
  I6J14_RS08585 (I6J14_08585) recA 1694521..1695657 (+) 1137 WP_115245519.1 recombinase RecA Machinery gene
  I6J14_RS08590 (I6J14_08590) spx 1695955..1696353 (+) 399 WP_003053105.1 transcriptional regulator Spx -
  I6J14_RS08595 (I6J14_08595) - 1696465..1696734 (+) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  I6J14_RS08600 (I6J14_08600) ruvX 1696731..1697150 (+) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  I6J14_RS08605 (I6J14_08605) - 1697161..1697466 (+) 306 WP_003053101.1 DUF1292 domain-containing protein -
  I6J14_RS08610 (I6J14_08610) - 1697812..1699374 (+) 1563 WP_115253189.1 DUF2079 domain-containing protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46086.57 Da        Isoelectric Point: 4.8249

>NTDB_id=526749 I6J14_RS08580 WP_115253190.1 1693192..1694463(+) (cinA) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDDFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNKVTYVVLPGPPSELKPM
VNEELLPLLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDQLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGIPLEDLTSYGVVSAYTAEKMAEQARLLTGADIGVSLTGVAGPDMLEDQPAGTVFIGLATQNKVESMKVLIGRRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=526749 I6J14_RS08580 WP_115253190.1 1693192..1694463(+) (cinA) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACTAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGTGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATACCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTAGACGATTTTTATGCCAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TCGCAGTGGGGGGCTTAATCACTGTTAATAAGGTGACTTATGTTGTTTTACCAGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTCTTTTGTCCACACAATCTCGCAAACTTTACTCGAGAGTCTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGACCCTACCATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCAACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGAGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCATTCCTCTAGAGGATTTGACATCGTATGGAGTTGTTAGTGCTTATACGGCTGAGAAGATGGCGGAGCAAGCAAG
ATTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGACCAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATCGGGAGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.104

100

0.721
  cinA Streptococcus mitis SK321

70.983

98.582

0.7
  cinA Streptococcus mitis NCTC 12261

70.024

98.582

0.69
  cinA Streptococcus pneumoniae TIGR4

69.065

98.582

0.681
  cinA Streptococcus pneumoniae Rx1

69.065

98.582

0.681
  cinA Streptococcus pneumoniae R6

69.065

98.582

0.681
  cinA Streptococcus pneumoniae D39

68.825

98.582

0.678
  cinA Streptococcus suis isolate S10

53.846

98.345

0.53
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

98.818

0.452