Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SMUGS5_RS09455 Genome accession   NC_018089
Coordinates   1951426..1952682 (-) Length   418 a.a.
NCBI ID   WP_002270966.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1946426..1957682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS09415 (SMUGS5_09350) - 1946621..1946920 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  SMUGS5_RS09420 (SMUGS5_09355) ruvX 1947001..1947420 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  SMUGS5_RS09425 (SMUGS5_09360) - 1947417..1947686 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUGS5_RS09430 (SMUGS5_09365) brsR 1947854..1948288 (+) 435 WP_002280522.1 bacteriocin genes transcriptional regulator BrsR Regulator
  SMUGS5_RS09435 (SMUGS5_09370) brsM 1948301..1948746 (+) 446 Protein_1835 bacteriocin genes regulator BrsM -
  SMUGS5_RS10265 (SMUGS5_09375) - 1948737..1948949 (-) 213 WP_002262389.1 hypothetical protein -
  SMUGS5_RS09440 (SMUGS5_09380) - 1949076..1949501 (-) 426 WP_002264551.1 hypothetical protein -
  SMUGS5_RS09445 (SMUGS5_09385) spx 1949752..1950150 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUGS5_RS09450 (SMUGS5_09390) recA 1950235..1951386 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUGS5_RS09455 (SMUGS5_09395) cinA 1951426..1952682 (-) 1257 WP_002270966.1 competence/damage-inducible protein A Machinery gene
  SMUGS5_RS09460 (SMUGS5_09400) - 1952831..1953391 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  SMUGS5_RS09465 (SMUGS5_09405) ruvA 1953473..1954066 (-) 594 WP_014835067.1 Holliday junction branch migration protein RuvA -
  SMUGS5_RS09470 (SMUGS5_09410) mutL 1954254..1956209 (-) 1956 WP_002280521.1 DNA mismatch repair endonuclease MutL -
  SMUGS5_RS10270 - 1956434..1956712 (+) 279 Protein_1844 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45704.48 Da        Isoelectric Point: 6.2714

>NTDB_id=52071 SMUGS5_RS09455 WP_002270966.1 1951426..1952682(-) (cinA) [Streptococcus mutans GS-5]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IVTIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=52071 SMUGS5_RS09455 WP_002270966.1 1951426..1952682(-) (cinA) [Streptococcus mutans GS-5]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGTT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTGTAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.522

100

0.995
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.005

98.804

0.455

Multiple sequence alignment