Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SMUGS5_RS09430 Genome accession   NC_018089
Coordinates   1947854..1948288 (+) Length   144 a.a.
NCBI ID   WP_002280522.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1942854..1953288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS09405 (SMUGS5_09340) - 1944816..1946387 (-) 1572 WP_042899569.1 membrane protein -
  SMUGS5_RS09415 (SMUGS5_09350) - 1946621..1946920 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  SMUGS5_RS09420 (SMUGS5_09355) ruvX 1947001..1947420 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  SMUGS5_RS09425 (SMUGS5_09360) - 1947417..1947686 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUGS5_RS09430 (SMUGS5_09365) brsR 1947854..1948288 (+) 435 WP_002280522.1 bacteriocin genes transcriptional regulator BrsR Regulator
  SMUGS5_RS09435 (SMUGS5_09370) brsM 1948301..1948746 (+) 446 Protein_1835 bacteriocin genes regulator BrsM -
  SMUGS5_RS10265 (SMUGS5_09375) - 1948737..1948949 (-) 213 WP_002262389.1 hypothetical protein -
  SMUGS5_RS09440 (SMUGS5_09380) - 1949076..1949501 (-) 426 WP_002264551.1 hypothetical protein -
  SMUGS5_RS09445 (SMUGS5_09385) spx 1949752..1950150 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUGS5_RS09450 (SMUGS5_09390) recA 1950235..1951386 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUGS5_RS09455 (SMUGS5_09395) cinA 1951426..1952682 (-) 1257 WP_002270966.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 17171.19 Da        Isoelectric Point: 10.5565

>NTDB_id=52069 SMUGS5_RS09430 WP_002280522.1 1947854..1948288(+) (brsR) [Streptococcus mutans GS-5]
MKVKIIKDSNFKEPLLQIYTRHIDKQTQRVIDFIQQRPNIVYGYKNKCLEFIPLEKVIRIFTENKQVLIQTPTDTYLAKQ
RLYFFEQELGTPFIRISQGEIINIKYIKQLNLTIRGSIEVTFKNGTVSFVARRSLKRFKEQLNL

Nucleotide


Download         Length: 435 bp        

>NTDB_id=52069 SMUGS5_RS09430 WP_002280522.1 1947854..1948288(+) (brsR) [Streptococcus mutans GS-5]
ATGAAAGTAAAAATTATCAAGGATTCAAACTTTAAGGAACCCTTACTCCAAATCTATACACGTCATATTGATAAACAAAC
GCAGAGGGTGATTGATTTTATTCAACAAAGACCTAATATCGTTTATGGTTACAAAAATAAATGCTTAGAGTTTATCCCAC
TAGAAAAAGTGATTCGTATTTTCACGGAAAACAAACAGGTCTTAATTCAAACACCAACCGATACCTATTTAGCTAAACAA
AGACTCTACTTTTTTGAGCAAGAATTAGGAACACCTTTTATTCGTATCTCCCAAGGTGAAATCATCAATATCAAATATAT
TAAACAATTGAATTTAACCATCCGAGGCAGCATTGAAGTGACTTTCAAAAATGGAACAGTCAGTTTTGTGGCTAGGCGAA
GTTTGAAACGCTTCAAAGAACAATTAAATCTTTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(50-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

99.306

100

0.993

Multiple sequence alignment