Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   IGS65_RS07210 Genome accession   NZ_CP066294
Coordinates   1456287..1457543 (-) Length   418 a.a.
NCBI ID   WP_002266115.1    Uniprot ID   -
Organism   Streptococcus mutans strain 27-3     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1451287..1462543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS65_RS07165 (IGS65_007165) - 1451479..1451778 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  IGS65_RS07170 (IGS65_007170) ruvX 1451859..1452278 (-) 420 WP_002284631.1 Holliday junction resolvase RuvX -
  IGS65_RS07175 (IGS65_007175) - 1452275..1452544 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  IGS65_RS07180 (IGS65_007180) brsR 1452712..1453146 (+) 435 WP_002284632.1 bacteriocin genes transcriptional regulator BrsR Regulator
  IGS65_RS07185 (IGS65_007185) brsM 1453159..1453605 (+) 447 WP_002266978.1 bacteriocin genes regulator BrsM Regulator
  IGS65_RS07190 (IGS65_007190) - 1453596..1453807 (-) 212 Protein_1408 hypothetical protein -
  IGS65_RS07195 (IGS65_007195) - 1453936..1454361 (-) 426 WP_002266116.1 hypothetical protein -
  IGS65_RS07200 (IGS65_007200) spx 1454613..1455011 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  IGS65_RS07205 (IGS65_007205) recA 1455096..1456247 (-) 1152 WP_002288707.1 recombinase RecA Machinery gene
  IGS65_RS07210 (IGS65_007210) cinA 1456287..1457543 (-) 1257 WP_002266115.1 competence/damage-inducible protein A Machinery gene
  IGS65_RS07215 (IGS65_007215) - 1457692..1458252 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  IGS65_RS07220 (IGS65_007220) ruvA 1458334..1458927 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  IGS65_RS07225 (IGS65_007225) mutL 1459110..1461065 (-) 1956 WP_192072428.1 DNA mismatch repair endonuclease MutL -
  IGS65_RS07230 (IGS65_007230) - 1461290..1461569 (+) 280 Protein_1416 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45718.51 Da        Isoelectric Point: 6.2714

>NTDB_id=519146 IGS65_RS07210 WP_002266115.1 1456287..1457543(-) (cinA) [Streptococcus mutans strain 27-3]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=519146 IGS65_RS07210 WP_002266115.1 1456287..1457543(-) (cinA) [Streptococcus mutans strain 27-3]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGCGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
TTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACGCCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCCTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAAGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.761

100

0.998
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452