Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   JDY60_RS09315 Genome accession   NZ_CP066172
Coordinates   1940007..1941263 (+) Length   418 a.a.
NCBI ID   WP_200370822.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1941318..1968927 1940007..1941263 flank 55


Gene organization within MGE regions


Location: 1940007..1968927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS09315 (JDY60_09315) cinA 1940007..1941263 (+) 1257 WP_200370822.1 competence/damage-inducible protein A Machinery gene
  JDY60_RS09320 (JDY60_09320) recA 1941318..1942469 (+) 1152 WP_001085517.1 recombinase RecA Machinery gene
  JDY60_RS09325 (JDY60_09325) - 1942639..1942833 (+) 195 WP_000415528.1 PspC domain-containing protein -
  JDY60_RS09330 (JDY60_09330) - 1942963..1943517 (-) 555 WP_000060286.1 GNAT family N-acetyltransferase -
  JDY60_RS09335 (JDY60_09335) - 1943627..1944997 (+) 1371 WP_200370823.1 MATE family efflux transporter -
  JDY60_RS09340 (JDY60_09340) - 1945094..1945810 (+) 717 WP_000532894.1 YebC/PmpR family DNA-binding transcriptional regulator -
  JDY60_RS09345 (JDY60_09345) - 1945898..1947019 (-) 1122 WP_233848250.1 site-specific integrase -
  JDY60_RS09670 (JDY60_09350) - 1947389..1947586 (-) 198 Protein_1807 restriction endonuclease -
  JDY60_RS09355 (JDY60_09355) - 1947599..1947979 (-) 381 WP_015971699.1 ImmA/IrrE family metallo-endopeptidase -
  JDY60_RS09360 (JDY60_09360) - 1947983..1948336 (-) 354 WP_015971700.1 helix-turn-helix domain-containing protein -
  JDY60_RS09655 - 1948624..1948752 (+) 129 WP_015971701.1 hypothetical protein -
  JDY60_RS09365 (JDY60_09365) - 1948767..1948979 (+) 213 WP_015971702.1 hypothetical protein -
  JDY60_RS09370 (JDY60_09370) - 1948955..1949635 (-) 681 WP_015971703.1 DUF4145 domain-containing protein -
  JDY60_RS09375 (JDY60_09375) - 1949690..1949899 (+) 210 WP_015971704.1 helix-turn-helix transcriptional regulator -
  JDY60_RS09380 (JDY60_09380) - 1949903..1950100 (+) 198 WP_015971705.1 hypothetical protein -
  JDY60_RS09385 (JDY60_09385) - 1950217..1950876 (-) 660 WP_015971707.1 hypothetical protein -
  JDY60_RS09390 (JDY60_09390) - 1950933..1951163 (+) 231 WP_015971708.1 hypothetical protein -
  JDY60_RS09395 (JDY60_09395) - 1951276..1951959 (-) 684 WP_233848252.1 DUF4145 domain-containing protein -
  JDY60_RS09400 (JDY60_09400) - 1952008..1952727 (+) 720 WP_015971710.1 ORF6C domain-containing protein -
  JDY60_RS09405 (JDY60_09405) - 1952810..1953082 (+) 273 WP_015971711.1 hypothetical protein -
  JDY60_RS09410 (JDY60_09410) - 1953132..1953389 (+) 258 WP_015971712.1 hypothetical protein -
  JDY60_RS09415 (JDY60_09415) - 1953405..1953833 (+) 429 WP_015971713.1 hypothetical protein -
  JDY60_RS09420 (JDY60_09420) - 1953853..1954650 (+) 798 WP_015971714.1 phage replisome organizer N-terminal domain-containing protein -
  JDY60_RS09425 (JDY60_09425) - 1954638..1954796 (+) 159 WP_015971715.1 hypothetical protein -
  JDY60_RS09430 (JDY60_09430) - 1954790..1955560 (+) 771 WP_015971716.1 ATP-binding protein -
  JDY60_RS09640 - 1955575..1955805 (+) 231 Protein_1825 hypothetical protein -
  JDY60_RS09435 (JDY60_09435) - 1955907..1956380 (+) 474 WP_015971717.1 Cas9 inhibitor AcrIIA9 family protein -
  JDY60_RS09440 (JDY60_09440) - 1956380..1957738 (+) 1359 WP_200370824.1 PcfJ domain-containing protein -
  JDY60_RS09445 (JDY60_09445) - 1957758..1958084 (+) 327 WP_015971719.1 hypothetical protein -
  JDY60_RS09450 (JDY60_09450) - 1958118..1958378 (+) 261 WP_015971720.1 hypothetical protein -
  JDY60_RS09455 (JDY60_09455) - 1958375..1958716 (+) 342 WP_015971721.1 HNH endonuclease -
  JDY60_RS09460 (JDY60_09460) - 1958713..1958973 (+) 261 WP_015971722.1 DUF1372 family protein -
  JDY60_RS09465 (JDY60_09465) - 1958970..1959449 (+) 480 WP_233848254.1 hypothetical protein -
  JDY60_RS09470 (JDY60_09470) - 1959470..1959721 (+) 252 WP_015971724.1 DUF3310 domain-containing protein -
  JDY60_RS09475 (JDY60_09475) - 1959699..1959863 (+) 165 WP_015971725.1 hypothetical protein -
  JDY60_RS09480 (JDY60_09480) - 1959883..1960308 (+) 426 WP_015971726.1 ArpU family phage packaging/lysis transcriptional regulator -
  JDY60_RS09485 (JDY60_09485) - 1960421..1960987 (+) 567 WP_015971727.1 site-specific integrase -
  JDY60_RS09490 (JDY60_09490) - 1961199..1961543 (+) 345 WP_015971728.1 HNH endonuclease signature motif containing protein -
  JDY60_RS09495 (JDY60_09495) - 1961748..1963016 (+) 1269 WP_200370828.1 phage portal protein -
  JDY60_RS09500 (JDY60_09500) - 1963006..1964211 (+) 1206 WP_200370831.1 hypothetical protein -
  JDY60_RS09505 (JDY60_09505) - 1964201..1964380 (+) 180 WP_015971731.1 CPCC family cysteine-rich protein -
  JDY60_RS09510 (JDY60_09510) - 1964543..1964794 (+) 252 WP_015971732.1 DUF6275 family protein -
  JDY60_RS09515 (JDY60_09515) - 1964858..1966270 (+) 1413 WP_200370832.1 terminase -
  JDY60_RS09520 (JDY60_09520) - 1966351..1966818 (+) 468 WP_200370833.1 DUF4355 domain-containing protein -
  JDY60_RS09525 (JDY60_09525) - 1966831..1967733 (+) 903 WP_015971735.1 phage major capsid protein -
  JDY60_RS09530 (JDY60_09530) - 1967736..1967957 (+) 222 WP_015971736.1 HeH/LEM domain-containing protein -
  JDY60_RS09535 (JDY60_09535) - 1967978..1968373 (+) 396 WP_015971737.1 phage Gp19/Gp15/Gp42 family protein -
  JDY60_RS09540 (JDY60_09540) - 1968360..1968698 (+) 339 WP_015971738.1 hypothetical protein -
  JDY60_RS09545 (JDY60_09545) - 1968691..1968927 (+) 237 WP_015971739.1 hypothetical protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45291.63 Da        Isoelectric Point: 4.8464

>NTDB_id=518097 JDY60_RS09315 WP_200370822.1 1940007..1941263(+) (cinA) [Streptococcus oralis strain SF100]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKDLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVSEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGTKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKAVNQEKADQALDILENQI
LDRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DIYEQELKEHGVVSEFTARKMAEQARIKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=518097 JDY60_RS09315 WP_200370822.1 1940007..1941263(+) (cinA) [Streptococcus oralis strain SF100]
ATGAAAGCAGAAATTATTGCTGTTGGAACAGAAATTTTAACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGATGTCTACTTCCAAACAGCTGTTGGAGATAATGAAGCTCGTCTTTTGTCCTTGCTTG
AGATTGCGAGTCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACCGAGGATGATTTGACCAAACAAACC
CTGGCAAAATTTTTGGGAAAAGATCTAGTGTTTGACCCTCAAGCGCAAGAGAAACTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCGACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGGGTGTCGGAAGTGGATGGCGTGACCTACGTGGTCCTCCCAGGACCACCTAGTGAATTGAAACCTATG
GTCTTAAATCAACTCTTACCCAAGTTAATGACTGGTACCAAGTTATACTCACGAGTGCTCCGTTTCTTTGGAATTGGGGA
GAGTCAGTTGGTGACCATTTTGGCGGATTTAATTGACCATCAAACCGATCCGACTTTGGCGCCGTATGCTAAGACGGGAG
AAGTGACCTTGCGCTTGTCTACAAAAGCAGTCAATCAAGAAAAGGCTGATCAAGCACTGGACATCCTAGAAAATCAAATC
TTGGATCGCCAGACTTTTGAGGGAATTTCTCTACGAGACATCTGTTACGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAAGCAACAT
TAGCAGACTTTTCGGGCGTTTCAGCAATCTTTAATGGCGGTTTTGTCACTTACAGCCTAGAAGAAAAGTCTAAGATGTTG
GATATTTACGAGCAAGAGCTAAAAGAACACGGGGTCGTTTCTGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGAT
CAAGACTCAGTCTGATTATGGTGTCAGTCTGACAGGTGTAGCTGGGCCAGATAGCCTAGAGGGTCATCCAGCTGGTACAG
TTTTTATTGGACTGGCACATGCCAAAGGGACAGAGGTGATCAAGGCCAATATAGCAGGACGGAGTCGAGCAGATGTTCGA
CATATTGCGGTCATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.952

100

0.9
  cinA Streptococcus pneumoniae TIGR4

89.713

100

0.897
  cinA Streptococcus pneumoniae Rx1

89.713

100

0.897
  cinA Streptococcus pneumoniae R6

89.713

100

0.897
  cinA Streptococcus pneumoniae D39

89.474

100

0.895
  cinA Streptococcus mitis NCTC 12261

89.234

100

0.892
  cinA Streptococcus mutans UA159

70.574

100

0.706
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455