Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ITG10_RS04955 Genome accession   NZ_CP066149
Coordinates   1161301..1162530 (+) Length   409 a.a.
NCBI ID   WP_017629808.1    Uniprot ID   -
Organism   Vibrio sp. ED004     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1156301..1167530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ITG10_RS04935 (ITG10_04870) ampD 1157316..1157915 (-) 600 WP_017629812.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ITG10_RS04940 (ITG10_04875) nadC 1157999..1158889 (+) 891 WP_017629811.1 carboxylating nicotinate-nucleotide diphosphorylase -
  ITG10_RS04945 (ITG10_04880) - 1159145..1159600 (+) 456 WP_017629810.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  ITG10_RS04950 (ITG10_04885) pilB 1159600..1161285 (+) 1686 WP_248386737.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ITG10_RS04955 (ITG10_04890) pilC 1161301..1162530 (+) 1230 WP_017629808.1 type II secretion system F family protein Machinery gene
  ITG10_RS04960 (ITG10_04895) pilD 1162598..1163467 (+) 870 WP_017629807.1 A24 family peptidase Machinery gene
  ITG10_RS04965 (ITG10_04900) coaE 1163470..1164084 (+) 615 WP_017629806.1 dephospho-CoA kinase -
  ITG10_RS04970 (ITG10_04905) zapD 1164111..1164851 (+) 741 WP_017629805.1 cell division protein ZapD -
  ITG10_RS04975 (ITG10_04910) yacG 1164932..1165129 (+) 198 WP_017106879.1 DNA gyrase inhibitor YacG -
  ITG10_RS04980 (ITG10_04915) - 1165379..1166397 (+) 1019 Protein_981 IS110 family transposase -
  ITG10_RS04985 - 1167102..1167494 (-) 393 WP_348983555.1 transposase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45189.26 Da        Isoelectric Point: 10.1582

>NTDB_id=517863 ITG10_RS04955 WP_017629808.1 1161301..1162530(+) (pilC) [Vibrio sp. ED004]
MSSKSKQSQLKSYHWKGINSSGKKVSGQTLALTELEVREKLKDQHIQIKKIKKKSISALTRLTHRVKPKDITILTRQLAT
MLATGVPIVQAIKLVSDNHRKAEMKSILSHICKGVEAGTPISKAMRTASRHFDDLYTDLVATGELSGNLAQVFERLATYR
EKSEQLKSKVIKALIYPAMVVIVALTVSYLMLTMVIPEFESMFSGFGADLPWFTQQVLHLSHWMQAYSFYAAVGIGLLAL
LVHQLCQRSYSIRLSASRLGLRFPVLGGVMAKASIAKFSRTLSTSFSSGIPILMSLKTTAKTAGNLHYESAIIEVHRETA
AGMPMYIAMRNTNAFPEMVLQMVMIGEESGNLDDMLNKVASIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLP
IFNLMSVLG

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=517863 ITG10_RS04955 WP_017629808.1 1161301..1162530(+) (pilC) [Vibrio sp. ED004]
ATGAGCAGTAAGTCCAAGCAATCACAACTAAAAAGCTATCATTGGAAAGGCATTAATAGCTCAGGCAAGAAAGTGTCTGG
TCAAACCTTAGCGCTCACCGAATTAGAGGTGCGAGAAAAGCTCAAAGATCAGCACATTCAAATCAAGAAAATCAAAAAGA
AAAGCATCTCAGCGCTGACTCGTTTAACGCACCGTGTAAAACCTAAAGACATCACTATTTTGACTCGACAACTTGCGACT
ATGTTGGCTACTGGTGTCCCTATCGTACAGGCTATCAAGTTAGTATCAGACAACCATCGCAAAGCTGAGATGAAATCTAT
CTTGTCGCATATCTGTAAAGGCGTGGAAGCAGGCACTCCGATTTCAAAAGCCATGCGCACCGCAAGTCGTCACTTTGATG
ATCTGTATACCGACTTAGTTGCGACAGGAGAACTCTCAGGAAACCTAGCGCAAGTATTCGAACGCCTAGCAACCTATAGA
GAAAAGAGTGAACAGTTAAAATCTAAGGTTATAAAAGCACTTATTTACCCAGCGATGGTGGTCATTGTTGCACTGACTGT
CTCTTACCTAATGCTGACCATGGTTATTCCCGAATTTGAATCGATGTTTTCAGGGTTTGGCGCCGATCTCCCTTGGTTTA
CCCAACAAGTTCTTCATCTTTCTCATTGGATGCAGGCTTACAGTTTTTATGCCGCTGTGGGCATTGGCTTGCTGGCACTA
TTAGTCCATCAATTGTGCCAGCGCTCTTACTCGATTCGCTTGTCAGCCAGCCGCTTAGGGTTACGATTTCCGGTGCTTGG
TGGTGTGATGGCCAAAGCCTCTATTGCGAAATTCAGCCGCACCTTATCAACCAGTTTTAGTTCTGGTATTCCGATTCTCA
TGAGCCTTAAAACCACCGCCAAAACCGCAGGCAATTTGCATTATGAATCGGCGATCATTGAGGTTCACCGCGAAACGGCA
GCTGGAATGCCTATGTATATCGCGATGCGTAATACCAATGCCTTCCCCGAGATGGTGTTGCAGATGGTGATGATTGGGGA
GGAGTCAGGCAACCTTGACGATATGCTTAATAAAGTGGCCTCGATTTACGAGTTTGAAGTCGACAACACCGTCGATAATC
TGGGCAAGATCTTAGAGCCATTGATCATCGTGTTTTTAGGAACGGTTGTTGGCGGGCTTGTGGTTGCGATGTACTTACCG
ATCTTTAATCTTATGAGTGTGTTAGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(75-197)

Type II secretion system (T2SS), protein F (T2SSF)

(278-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

80.5

97.8

0.787
  pilC Vibrio campbellii strain DS40M4

73.529

99.756

0.733
  pilC Acinetobacter baylyi ADP1

41.809

100

0.418
  pilC Acinetobacter baumannii D1279779

41.832

98.778

0.413
  pilC Legionella pneumophila strain ERS1305867

42

97.8

0.411
  pilC Pseudomonas stutzeri DSM 10701

41.162

96.822

0.399
  pilG Neisseria gonorrhoeae MS11

39.85

97.555

0.389
  pilG Neisseria meningitidis 44/76-A

39.599

97.555

0.386