Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   I6H43_RS12780 Genome accession   NZ_CP066092
Coordinates   2731312..2732553 (-) Length   413 a.a.
NCBI ID   WP_042033196.1    Uniprot ID   A0AAQ0ECD4
Organism   Aeromonas jandaei strain FDAARGOS_986     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2726312..2737553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H43_RS12755 (I6H43_12755) mutT 2728343..2728747 (+) 405 WP_042033189.1 8-oxo-dGTP diphosphatase MutT -
  I6H43_RS12760 (I6H43_12760) yacG 2728820..2729014 (-) 195 WP_005336142.1 DNA gyrase inhibitor YacG -
  I6H43_RS12765 (I6H43_12765) zapD 2729024..2729746 (-) 723 WP_042033191.1 cell division protein ZapD -
  I6H43_RS12770 (I6H43_12770) coaE 2729791..2730399 (-) 609 WP_042033194.1 dephospho-CoA kinase -
  I6H43_RS12775 (I6H43_12775) pilD 2730417..2731289 (-) 873 WP_042033195.1 A24 family peptidase Machinery gene
  I6H43_RS12780 (I6H43_12780) pilC 2731312..2732553 (-) 1242 WP_042033196.1 type II secretion system F family protein Machinery gene
  I6H43_RS12785 (I6H43_12785) pilB 2732699..2734405 (-) 1707 WP_033115377.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  I6H43_RS21440 (I6H43_12790) - 2734409..2734837 (-) 429 WP_042033198.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  I6H43_RS12795 (I6H43_12795) nadC 2735160..2736017 (-) 858 WP_042033200.1 carboxylating nicotinate-nucleotide diphosphorylase -
  I6H43_RS12800 (I6H43_12800) - 2736021..2736491 (-) 471 WP_042033202.1 TIGR02281 family clan AA aspartic protease -
  I6H43_RS12805 (I6H43_12805) ampD 2736615..2737184 (+) 570 WP_042033204.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45410.60 Da        Isoelectric Point: 9.7221

>NTDB_id=517312 I6H43_RS12780 WP_042033196.1 2731312..2732553(-) (pilC) [Aeromonas jandaei strain FDAARGOS_986]
MATLTKKTNAPKKVFAFRWQGVNRKGQKVSGELQAENIATVKAELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGEIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTQFVIGISRFMQNWWYVFFGGIA
LAIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=517312 I6H43_RS12780 WP_042033196.1 2731312..2732553(-) (pilC) [Aeromonas jandaei strain FDAARGOS_986]
ATGGCAACGCTGACCAAGAAAACCAATGCCCCGAAAAAAGTCTTCGCCTTTCGCTGGCAAGGGGTAAACCGCAAAGGACA
AAAAGTCTCTGGCGAGCTTCAAGCAGAGAACATAGCCACAGTGAAGGCAGAGCTGCGCAAGCAGGGCGTCAATGTCACCA
AGGTTGCCAAGAAGAGTCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAACCGATGGATATTGCCATCGTATCGCGC
CAGATCACTACCATGCTCTCCGCCGGCGTTCCTCTGGTACAAAGCCTGCAAATCATCGCCCGCAGCCACGAAAAAGCATC
CATGCGCGAACTTATGGGAGAAATTGCCGCTGATGTCGAAACCGGCACCCCCATGTCGGAAGCGCTGCGCCGTCATCCTC
TCTACTTTGACGATCTCTATTGCGATCTAGTGGAAGCTGGCGAGCAGTCCGGCGCGCTGGAAACCATCTATGACCGCATC
GCTACCTACCGCGAGAAATCAGAAGCACTCAAGTCGAAGATCAAGAAGGCGATGTTCTACCCAACCATGGTTATCCTGGT
TGCGATTGTCGTTACCTCCATCCTGTTGCTGTTCGTCATCCCGCAATTCGAAGATATCTTCAAAAGCTTCGGTGCCGAGC
TGCCTGCATTTACGCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTACGTTTTCTTCGGCGGAATCGCG
CTGGCCATCTTTCTCTATGTCCGTGCCTGGCGAGCCTCCCAGAAGGTAAAAGACAATACCGACAAGTTTGTGCTCACGAT
TCCGGTAGTCGGGATGATCCTGCACAAAGCAGCCATGGCCCGCTTTGCCCGCACCCTATCCACCACCTTCTCGGCGGGGA
TTCCACTGGTCGATGCCTTGGTTTCAGCTGCTGGCGCCTCAGGTAACTATGTCTATCGCACCGCCGTGATGGCCATTCGC
AACGAGGTGGTAGCCGGCATGCAGATCAACGTGGCGATGAGGACCGTCGATCTTTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCCGGCGCCATAGATGATATGCTCTCCAAGGTCGCCACCATCTTTGAACAGGAGGTCGACGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCTCTTATCATGGTGGTACTGGGGGTGCTGGTTGGCGGTATGGTGGTTGCC
ATGTATCTGCCCATCTTTAAACTGGGGTCAGTTATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.828

95.884

0.554
  pilC Acinetobacter baumannii D1279779

54.5

96.852

0.528
  pilC Acinetobacter baylyi ADP1

53.401

96.126

0.513
  pilC Legionella pneumophila strain ERS1305867

51.98

97.821

0.508
  pilC Vibrio campbellii strain DS40M4

46.437

98.547

0.458
  pilC Vibrio cholerae strain A1552

46.985

96.368

0.453
  pilG Neisseria meningitidis 44/76-A

40.741

98.063

0.4
  pilG Neisseria gonorrhoeae MS11

40.741

98.063

0.4
  pilC Thermus thermophilus HB27

38

96.852

0.368