Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   I6H77_RS03380 Genome accession   NZ_CP066021
Coordinates   697152..698168 (-) Length   338 a.a.
NCBI ID   WP_002875106.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 692152..703168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS03340 (I6H77_03340) - 692474..693664 (-) 1191 WP_000167789.1 acetate kinase -
  I6H77_RS03345 (I6H77_03345) comYH 693716..694669 (-) 954 WP_000345144.1 class I SAM-dependent methyltransferase Machinery gene
  I6H77_RS03350 (I6H77_03350) - 694730..695317 (-) 588 WP_000679790.1 class I SAM-dependent methyltransferase -
  I6H77_RS03355 (I6H77_03355) comGG/cglG 695350..695763 (-) 414 WP_000265647.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6H77_RS03360 (I6H77_03360) comGF/cglF 695741..696202 (-) 462 WP_002875275.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H77_RS03365 (I6H77_03365) comGE/cglE 696165..696467 (-) 303 WP_000413369.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H77_RS03370 (I6H77_03370) comGD/cglD 696430..696864 (-) 435 WP_001180060.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H77_RS03375 (I6H77_03375) comGC/cglC 696827..697150 (-) 324 WP_000735794.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H77_RS03380 (I6H77_03380) comGB/cglB 697152..698168 (-) 1017 WP_002875106.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H77_RS03385 (I6H77_03385) comGA/cglA/cilD 698116..699057 (-) 942 WP_000249583.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H77_RS03390 (I6H77_03390) - 699119..699484 (-) 366 WP_000286399.1 DUF1033 family protein -
  I6H77_RS03395 (I6H77_03395) nagA 699642..700793 (-) 1152 WP_001134442.1 N-acetylglucosamine-6-phosphate deacetylase -
  I6H77_RS03400 (I6H77_03400) - 700934..702751 (-) 1818 WP_001220886.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38657.80 Da        Isoelectric Point: 9.6790

>NTDB_id=516461 I6H77_RS03380 WP_002875106.1 697152..698168(-) (comGB/cglB) [Streptococcus oralis strain FDAARGOS_1020]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVAQMHQGLSQGKSFSEMMESLGFSSAI
VTQLSLAEVHGNLHLSLRKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARVPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGREFSQTITTYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWESFFIRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=516461 I6H77_RS03380 WP_002875106.1 697152..698168(-) (comGB/cglB) [Streptococcus oralis strain FDAARGOS_1020]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACTTTGTTTAA
CAACCTCTTCTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTTTTGGGCAGAAGTGCCTTGCTGGAAAAGGACTATG
TGGCCCAGATGCACCAAGGATTGTCTCAGGGGAAATCCTTTTCAGAAATGATGGAAAGTTTGGGCTTTTCAAGTGCCATT
GTGACCCAATTATCTCTAGCTGAAGTACATGGAAATCTTCACCTGAGTCTGAGGAAGATAGAAGAATATCTGGATAATTT
GGCCAAGGTCAAGAAAAAGTTAATCGAAGTGGCGACTTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GGTTGAGAAACTATCTACTTCCCCAACTGGACAGTAGCAATATTGCCACTCAAATCATCGGCAATCTGCCACAAATATTT
CTGGGACTAGTGCTGGTTTGCTCTCTATCTTTACTTTTAGCCCTCACTTTCTACAAAAGAAGTTCCAAGATGCGGGTTTT
CTCGATGTTGGCACGGGTTCCCTTTCTAGGAATCTTTGTCCAGACCTATCTGACGGCCTATTACGCGCGTGAATGGGGCA
ATATGATTTCACAGGGGATGGAGCTGACGCAAATTTTTCAGATCATGCAGGAACAAGGTTCTCAGCTCTTTAAAGAAATC
GGTCAAGATTTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAACGACCTATCCTTTCTTTAAGAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTACGCGGAAAAGACTTGGG
AATCCTTTTTTATCCGAGTCAACCGCACCATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

92.899

100

0.929
  comGB/cglB Streptococcus mitis NCTC 12261

92.308

100

0.923
  comGB/cglB Streptococcus pneumoniae Rx1

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae D39

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae R6

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae TIGR4

90.828

100

0.908
  comYB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comYB Streptococcus mutans UA140

59.248

94.379

0.559
  comYB Streptococcus mutans UA159

59.248

94.379

0.559
  comGB Lactococcus lactis subsp. cremoris KW2

52.663

100

0.527