Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   I6H77_RS03360 Genome accession   NZ_CP066021
Coordinates   695741..696202 (-) Length   153 a.a.
NCBI ID   WP_002875275.1    Uniprot ID   A0A1X1HB00
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 690741..701202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS03330 (I6H77_03330) - 691151..691978 (-) 828 WP_000728097.1 membrane protein insertase YidC -
  I6H77_RS03335 (I6H77_03335) rnpA 691953..692324 (-) 372 WP_000748120.1 ribonuclease P protein component -
  I6H77_RS03340 (I6H77_03340) - 692474..693664 (-) 1191 WP_000167789.1 acetate kinase -
  I6H77_RS03345 (I6H77_03345) comYH 693716..694669 (-) 954 WP_000345144.1 class I SAM-dependent methyltransferase Machinery gene
  I6H77_RS03350 (I6H77_03350) - 694730..695317 (-) 588 WP_000679790.1 class I SAM-dependent methyltransferase -
  I6H77_RS03355 (I6H77_03355) comGG/cglG 695350..695763 (-) 414 WP_000265647.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6H77_RS03360 (I6H77_03360) comGF/cglF 695741..696202 (-) 462 WP_002875275.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H77_RS03365 (I6H77_03365) comGE/cglE 696165..696467 (-) 303 WP_000413369.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H77_RS03370 (I6H77_03370) comGD/cglD 696430..696864 (-) 435 WP_001180060.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H77_RS03375 (I6H77_03375) comGC/cglC 696827..697150 (-) 324 WP_000735794.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H77_RS03380 (I6H77_03380) comGB/cglB 697152..698168 (-) 1017 WP_002875106.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H77_RS03385 (I6H77_03385) comGA/cglA/cilD 698116..699057 (-) 942 WP_000249583.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H77_RS03390 (I6H77_03390) - 699119..699484 (-) 366 WP_000286399.1 DUF1033 family protein -
  I6H77_RS03395 (I6H77_03395) nagA 699642..700793 (-) 1152 WP_001134442.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 153 a.a.        Molecular weight: 17787.41 Da        Isoelectric Point: 9.6234

>NTDB_id=516457 I6H77_RS03360 WP_002875275.1 695741..696202(-) (comGF/cglF) [Streptococcus oralis strain FDAARGOS_1020]
MVQRSCSTLKSSKVRAFTLLESLIALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELERSQFEKVEGN
RLYLKQDGKDISIGKSKSDDFRKTDTSGRGYQPMVYGLKSAQITEENQLVRFRFQFQKGLEREFIYRVEKTKS

Nucleotide


Download         Length: 462 bp        

>NTDB_id=516457 I6H77_RS03360 WP_002875275.1 695741..696202(-) (comGF/cglF) [Streptococcus oralis strain FDAARGOS_1020]
ATGGTTCAGAGAAGTTGCTCGACCTTAAAGAGCAGTAAGGTAAGAGCGTTCACTCTATTAGAATCTCTGATTGCCCTTAT
CGTCATTAGCGGAGGCTTGCTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGTTACCAGCAGCAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTGGAGGCAGAGTTAGAGCGTTCGCAGTTTGAAAAGGTAGAAGGCAAT
CGCCTCTATTTAAAACAAGATGGTAAGGATATCTCTATAGGGAAGTCTAAATCGGATGATTTTCGAAAAACGGATACCAG
CGGACGGGGCTATCAGCCGATGGTTTATGGACTCAAATCAGCTCAAATTACAGAGGAAAATCAATTGGTTCGCTTTCGTT
TCCAATTTCAAAAGGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAACAAAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(45-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1HB00

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus mitis SK321

90.196

100

0.902
  comGF/cglF Streptococcus mitis NCTC 12261

88.889

100

0.889
  comGF/cglF Streptococcus pneumoniae Rx1

87.582

100

0.876
  comGF/cglF Streptococcus pneumoniae D39

87.582

100

0.876
  comGF/cglF Streptococcus pneumoniae R6

87.582

100

0.876
  comGF/cglF Streptococcus pneumoniae TIGR4

87.582

100

0.876
  comGF Lactococcus lactis subsp. cremoris KW2

41.429

91.503

0.379