Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   I6H77_RS03365 Genome accession   NZ_CP066021
Coordinates   696165..696467 (-) Length   100 a.a.
NCBI ID   WP_000413369.1    Uniprot ID   A0A1X1HB26
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 691165..701467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS03335 (I6H77_03335) rnpA 691953..692324 (-) 372 WP_000748120.1 ribonuclease P protein component -
  I6H77_RS03340 (I6H77_03340) - 692474..693664 (-) 1191 WP_000167789.1 acetate kinase -
  I6H77_RS03345 (I6H77_03345) comYH 693716..694669 (-) 954 WP_000345144.1 class I SAM-dependent methyltransferase Machinery gene
  I6H77_RS03350 (I6H77_03350) - 694730..695317 (-) 588 WP_000679790.1 class I SAM-dependent methyltransferase -
  I6H77_RS03355 (I6H77_03355) comGG/cglG 695350..695763 (-) 414 WP_000265647.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6H77_RS03360 (I6H77_03360) comGF/cglF 695741..696202 (-) 462 WP_002875275.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H77_RS03365 (I6H77_03365) comGE/cglE 696165..696467 (-) 303 WP_000413369.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H77_RS03370 (I6H77_03370) comGD/cglD 696430..696864 (-) 435 WP_001180060.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H77_RS03375 (I6H77_03375) comGC/cglC 696827..697150 (-) 324 WP_000735794.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H77_RS03380 (I6H77_03380) comGB/cglB 697152..698168 (-) 1017 WP_002875106.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H77_RS03385 (I6H77_03385) comGA/cglA/cilD 698116..699057 (-) 942 WP_000249583.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H77_RS03390 (I6H77_03390) - 699119..699484 (-) 366 WP_000286399.1 DUF1033 family protein -
  I6H77_RS03395 (I6H77_03395) nagA 699642..700793 (-) 1152 WP_001134442.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11124.08 Da        Isoelectric Point: 7.0157

>NTDB_id=516458 I6H77_RS03365 WP_000413369.1 696165..696467(-) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_1020]
MEKLNALRKLKIKAVILLEAVVALAVFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVNINGVEVQVFA
SEKGLEVYHGSEKLLDLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=516458 I6H77_RS03365 WP_000413369.1 696165..696467(-) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_1020]
ATGGAAAAATTAAACGCATTAAGGAAACTAAAAATTAAGGCAGTAATCTTACTAGAAGCAGTAGTAGCTTTGGCTGTGTT
TGCCAGCATTGCAACCCTCCTTTTAGGACAAATTCAGAAAAATAGACAAGAAGAGGCAGAAATCTTGCAAAAGGAAGAAG
TCTTGCGTGTGGCGAAGATGGCTCTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTGGAGGTTCAGGTGTTTGCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAGAAGTTGCTCGACCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1HB26

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae Rx1

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae D39

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae R6

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae TIGR4

89.899

99

0.89
  comGE/cglE Streptococcus mitis SK321

88.889

99

0.88
  comYE Streptococcus mutans UA140

43.478

92

0.4
  comYE Streptococcus mutans UA159

43.478

92

0.4