Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I6H76_RS06150 Genome accession   NZ_CP065994
Coordinates   1186025..1187284 (+) Length   419 a.a.
NCBI ID   WP_006531416.1    Uniprot ID   A0A380KPR3
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1181025..1192284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS06130 (I6H76_06130) mutL 1181465..1183405 (+) 1941 WP_006531420.1 DNA mismatch repair endonuclease MutL -
  I6H76_RS06135 (I6H76_06135) ruvA 1183406..1183999 (+) 594 WP_006531419.1 Holliday junction branch migration protein RuvA -
  I6H76_RS06140 (I6H76_06140) - 1184029..1184586 (+) 558 WP_043878298.1 DNA-3-methyladenine glycosylase I -
  I6H76_RS06145 (I6H76_06145) - 1184709..1185911 (+) 1203 WP_006531417.1 MFS transporter -
  I6H76_RS06150 (I6H76_06150) cinA 1186025..1187284 (+) 1260 WP_006531416.1 competence/damage-inducible protein A Machinery gene
  I6H76_RS06155 (I6H76_06155) recA 1187331..1188485 (+) 1155 WP_015695804.1 recombinase RecA Machinery gene
  I6H76_RS06160 (I6H76_06160) spx 1188683..1189081 (+) 399 WP_004233512.1 transcriptional regulator Spx -
  I6H76_RS06165 (I6H76_06165) - 1189403..1189672 (+) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  I6H76_RS06170 (I6H76_06170) ruvX 1189669..1190088 (+) 420 WP_006531414.1 Holliday junction resolvase RuvX -
  I6H76_RS06175 (I6H76_06175) - 1190121..1190438 (+) 318 WP_006531413.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45758.08 Da        Isoelectric Point: 5.0773

>NTDB_id=516141 I6H76_RS06150 WP_006531416.1 1186025..1187284(+) (cinA) [Streptococcus infantarius strain FDAARGOS_1019]
MKAEIIAVGTEILTGQITNTNAQFLSAEFAKLGIDVFFQTAVGDNEERLLSIIDLASKRSDLVVLCGGLGPTEDDLTKQT
LAKYLGRNLVFDEQASKRLNEFFATRPQFTRTANNERQAQLIEGSTPLQNSTGLAVGGVIEVDGVTYVVLPGPPSELKPM
VWDYLVPLLSSDHKQLYSRVLRFFGIGESQLVTVLSDLIDNQTDPTIAPYAKTGEVTLRLSTKADDIESAKEKLDQLEQK
ILSKKTLNSIPLENLLYGYGDDNSMARVVFDLLKKKHKTITAAESLTAGLFQSSIADFSGSSSVFNGGFVTYSIEEKSKM
LQIPLEELQEHGVVSHFTAEKMAEQSRKLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVLIGGRSRSDV
RHIACLYAFNLVRQALLQD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=516141 I6H76_RS06150 WP_006531416.1 1186025..1187284(+) (cinA) [Streptococcus infantarius strain FDAARGOS_1019]
ATGAAAGCTGAGATTATCGCTGTAGGAACAGAGATTTTAACAGGACAAATCACAAATACCAATGCGCAATTTTTATCTGC
AGAATTTGCCAAGTTAGGGATTGATGTTTTTTTCCAAACAGCTGTTGGGGACAATGAAGAGCGTCTTTTGTCTATCATTG
ATTTGGCAAGTAAGCGTAGCGATTTAGTTGTTCTCTGTGGTGGTTTAGGACCAACTGAGGATGATTTGACAAAGCAAACC
TTAGCAAAATATTTAGGGCGTAACCTGGTCTTTGACGAACAGGCAAGTAAACGTCTAAATGAGTTCTTTGCGACACGTCC
TCAATTTACAAGAACAGCTAACAATGAACGCCAAGCTCAACTGATTGAAGGTTCAACTCCTTTGCAAAATAGCACTGGTT
TGGCTGTAGGTGGAGTGATTGAAGTTGACGGCGTCACTTATGTTGTTCTTCCTGGCCCACCAAGTGAGCTTAAGCCCATG
GTCTGGGATTATTTAGTGCCTTTGTTATCTAGCGACCATAAGCAACTTTATTCACGTGTTTTGCGTTTCTTTGGCATAGG
AGAAAGCCAACTGGTAACTGTTTTATCAGATTTGATTGACAACCAAACTGATCCAACCATTGCGCCATATGCTAAGACAG
GTGAAGTAACGCTGCGTTTGTCAACGAAAGCAGACGACATTGAATCAGCTAAGGAAAAACTAGACCAGCTAGAGCAAAAA
ATTCTTTCTAAGAAGACTTTAAATAGCATTCCGCTTGAGAATTTGCTTTATGGTTATGGTGATGACAATAGTATGGCGCG
TGTTGTTTTTGATTTGCTTAAGAAAAAACACAAGACTATCACAGCTGCAGAAAGTTTAACAGCAGGGCTATTTCAATCAA
GTATTGCAGACTTCTCAGGCTCTTCATCAGTCTTTAATGGTGGTTTTGTGACTTATAGCATTGAAGAAAAATCAAAAATG
CTTCAGATTCCATTAGAAGAGTTGCAAGAACACGGGGTTGTTAGTCACTTTACAGCTGAGAAAATGGCTGAGCAATCTCG
CAAGTTAACAGATGCTGATTTTGGGATTGGATTGACAGGAGTTGCAGGACCAGATAGCTTAGAAGGTCACCCAGCGGGAA
CAGTTTTCATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTCTCATAGGTGGACGAAGCCGTTCAGATGTG
CGTCATATTGCATGTTTGTATGCATTTAACTTAGTACGTCAAGCTTTATTACAAGATTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-242)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KPR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.599

100

0.716
  cinA Streptococcus mutans UA159

71.703

99.523

0.714
  cinA Streptococcus mitis NCTC 12261

70.644

100

0.706
  cinA Streptococcus pneumoniae Rx1

69.69

100

0.697
  cinA Streptococcus pneumoniae TIGR4

69.69

100

0.697
  cinA Streptococcus pneumoniae R6

69.69

100

0.697
  cinA Streptococcus pneumoniae D39

69.451

100

0.695
  cinA Streptococcus suis isolate S10

54.327

99.284

0.539
  cinA Bacillus subtilis subsp. subtilis str. 168

45.972

100

0.463