Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   KWY62_RS03465 Genome accession   NZ_CP079193
Coordinates   683189..683851 (+) Length   220 a.a.
NCBI ID   WP_202847477.1    Uniprot ID   -
Organism   Streptococcus suis strain ID41570     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 678189..688851
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KWY62_RS03445 (KWY62_03445) - 678757..679686 (-) 930 WP_044674354.1 ABC transporter substrate-binding protein -
  KWY62_RS03450 (KWY62_03450) - 679699..680484 (-) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  KWY62_RS03455 (KWY62_03455) - 680784..682229 (-) 1446 WP_044674357.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  KWY62_RS03460 (KWY62_03460) - 682375..683121 (+) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  KWY62_RS03465 (KWY62_03465) comEA/celA/cilE 683189..683851 (+) 663 WP_202847477.1 helix-hairpin-helix domain-containing protein Machinery gene
  KWY62_RS03470 (KWY62_03470) comEC/celB 683835..686072 (+) 2238 WP_202847476.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  KWY62_RS03475 (KWY62_03475) holA 686168..687199 (+) 1032 WP_218981932.1 DNA polymerase III subunit delta -
  KWY62_RS03480 (KWY62_03480) sodA 687312..687917 (+) 606 WP_013730459.1 superoxide dismutase SodA -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23314.10 Da        Isoelectric Point: 4.1214

>NTDB_id=514279 KWY62_RS03465 WP_202847477.1 683189..683851(+) (comEA/celA/cilE) [Streptococcus suis strain ID41570]
MDTIKTYIEMLKGYKWQIALPAAAGLLMATFLIFSQPAKSDQTGLTDFPQTEQTLSSPEQLEEVSTEASEELSQLVIDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVIYVASKGENISVVASTTASSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=514279 KWY62_RS03465 WP_202847477.1 683189..683851(+) (comEA/celA/cilE) [Streptococcus suis strain ID41570]
ATGGATACGATTAAAACCTATATAGAAATGCTTAAAGGATACAAGTGGCAGATTGCCTTGCCCGCAGCAGCTGGCTTGCT
TATGGCGACGTTCTTAATATTCAGCCAACCAGCCAAGTCTGATCAGACAGGTCTGACAGATTTTCCGCAGACTGAACAAA
CTTTGAGCAGTCCGGAGCAGCTTGAAGAAGTCAGTACAGAAGCAAGTGAGGAGCTTAGTCAGCTAGTCATTGATGTCAAA
GGAGCGGTGGAAAAACCAGGACTTTACACCTTAGAAGCTGGTGCGCGTGTCAATGATGCTGTTGAGGCGGCTGGTGGCTT
GACTAGTCAGGCAGATCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGATCTATGTGGCTAGCAAGG
GCGAAAACATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCCCAAGAAGAAAAGAACACCAGTCTAGTCAAT
CTCAATACGGCGACCGAGGCGGACCTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAATGGCGGCTTCAAATCGGTGGACGACCTTAACAATGTTTCAGGCATTGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

45.815

100

0.473
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.032

99.545

0.468
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus pneumoniae D39

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus pneumoniae R6

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus mitis SK321

44.843

100

0.455
  comEA Streptococcus thermophilus LMD-9

58.642

73.636

0.432
  comEA Lactococcus lactis subsp. cremoris KW2

38.71

98.636

0.382
  comEA Bacillus subtilis subsp. subtilis str. 168

39.336

95.909

0.377