Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I8F59_RS13910 Genome accession   NZ_CP065784
Coordinates   2808425..2809669 (-) Length   414 a.a.
NCBI ID   WP_002424926.1    Uniprot ID   -
Organism   Enterococcus faecalis strain 18-243     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2803425..2814669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I8F59_RS13890 (I8F59_13890) - 2803895..2804281 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  I8F59_RS13895 (I8F59_13895) - 2804355..2805152 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  I8F59_RS13900 (I8F59_13900) rny 2805312..2806868 (-) 1557 WP_002354863.1 ribonuclease Y -
  I8F59_RS13905 (I8F59_13905) recA 2807265..2808311 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  I8F59_RS13910 (I8F59_13910) cinA 2808425..2809669 (-) 1245 WP_002424926.1 competence/damage-inducible protein A Machinery gene
  I8F59_RS13915 (I8F59_13915) - 2809861..2811066 (+) 1206 WP_002401127.1 hypothetical protein -
  I8F59_RS15460 - 2811293..2811397 (-) 105 Protein_2729 type II toxin-antitoxin system RelE/ParE family toxin -
  I8F59_RS15595 - 2811400..2811504 (-) 105 Protein_2730 antitoxin -
  I8F59_RS13920 (I8F59_13920) - 2812127..2812390 (-) 264 WP_002396818.1 hypothetical protein -
  I8F59_RS13925 (I8F59_13925) - 2812394..2814523 (-) 2130 WP_002424924.1 peptidase domain-containing ABC transporter -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45183.25 Da        Isoelectric Point: 4.6698

>NTDB_id=514231 I8F59_RS13910 WP_002424926.1 2808425..2809669(-) (cinA) [Enterococcus faecalis strain 18-243]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDSIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=514231 I8F59_RS13910 WP_002424926.1 2808425..2809669(-) (cinA) [Enterococcus faecalis strain 18-243]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAATTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGGACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTTACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACTCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.632

100

0.531
  cinA Streptococcus mitis SK321

51.773

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.537

100

0.527
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus pneumoniae R6

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.355

100

0.514
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.282

99.275

0.44