Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   SPAF_RS10300 Genome accession   NC_017905
Coordinates   2166309..2167067 (-) Length   252 a.a.
NCBI ID   WP_003018434.1    Uniprot ID   -
Organism   Streptococcus parasanguinis FW213     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2161309..2172067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPAF_RS10280 (Spaf_2103) - 2161765..2163387 (+) 1623 WP_013904364.1 ATP-binding cassette domain-containing protein -
  SPAF_RS10285 (Spaf_2104) - 2163440..2166007 (+) 2568 WP_014714106.1 YfhO family protein -
  SPAF_RS10300 (Spaf_2105) comE/comE2 2166309..2167067 (-) 759 WP_003018434.1 response regulator transcription factor Regulator
  SPAF_RS10305 (Spaf_2106) - 2167064..2168404 (-) 1341 WP_041826511.1 GHKL domain-containing protein -
  SPAF_RS10315 (Spaf_2107) rlmH 2168867..2169346 (-) 480 WP_014714108.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SPAF_RS10320 (Spaf_2108) htrA 2169551..2170732 (+) 1182 WP_013904367.1 S1C family serine protease Regulator
  SPAF_RS10325 (Spaf_2109) - 2170804..2171564 (+) 761 Protein_1990 ParB/RepB/Spo0J family partition protein -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 29604.16 Da        Isoelectric Point: 5.4869

>NTDB_id=51152 SPAF_RS10300 WP_003018434.1 2166309..2167067(-) (comE/comE2) [Streptococcus parasanguinis FW213]
MKIFLLEDELSQQIRVEKHIAEIAKELEIKLEVISTGKITEFENYIQHSEIHQLYFLDIHIQDNEYCGLEIAQKIREANP
YAIIVFITTKSEFASITYRYKVSALDFIDKNLNEDLFRLKIKECIEYLTTIQIGNDDLTDYFEYDFKDKKIKIPFKDILY
IETVGSAYKLNLVGKNFQKEIAGSLSDVLEKDVEERYFSPHQSFIVNRSMIIGMDKKKKQLLLKEGYSCPISRSNIKRVK
KLIEEQNLEFSA

Nucleotide


Download         Length: 759 bp        

>NTDB_id=51152 SPAF_RS10300 WP_003018434.1 2166309..2167067(-) (comE/comE2) [Streptococcus parasanguinis FW213]
ATGAAGATTTTTTTATTAGAAGATGAGCTCTCTCAACAGATACGGGTAGAAAAACATATTGCAGAAATTGCTAAGGAATT
AGAAATTAAACTTGAAGTGATTTCTACTGGTAAAATTACAGAATTTGAAAATTATATCCAGCATTCTGAGATCCACCAAT
TATATTTTCTAGATATTCACATCCAAGACAATGAGTATTGTGGGCTAGAAATTGCTCAAAAAATACGAGAAGCAAATCCT
TATGCCATTATTGTTTTTATTACTACAAAATCGGAATTTGCTTCTATTACCTATCGTTATAAAGTATCTGCCTTGGATTT
TATTGATAAAAATTTGAATGAAGATTTATTTAGATTAAAAATTAAGGAGTGTATTGAGTACTTGACAACTATTCAAATTG
GAAATGATGATTTGACAGATTATTTCGAGTATGATTTTAAAGATAAAAAAATTAAAATTCCATTTAAGGATATTCTTTAT
ATCGAAACGGTTGGTTCAGCTTATAAATTAAACTTAGTTGGGAAAAATTTTCAAAAAGAAATTGCAGGAAGTTTATCAGA
TGTTTTGGAGAAGGATGTGGAGGAGAGATATTTTAGTCCTCATCAATCTTTTATCGTAAATAGAAGTATGATCATTGGAA
TGGATAAGAAAAAGAAACAGCTGCTGTTGAAAGAAGGGTATTCTTGTCCAATTTCAAGAAGTAATATCAAACGTGTCAAA
AAATTAATTGAAGAGCAAAATTTAGAATTTAGTGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(29-120)

LytTr DNA-binding domain (LytTR)

(149-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

49.597

98.413

0.488
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

49.597

98.413

0.488
  comE Streptococcus pneumoniae Rx1

47.581

98.413

0.468
  comE Streptococcus pneumoniae D39

47.581

98.413

0.468
  comE Streptococcus pneumoniae R6

47.581

98.413

0.468
  comE Streptococcus pneumoniae TIGR4

47.581

98.413

0.468
  comE Streptococcus mitis NCTC 12261

47.581

98.413

0.468
  comE Streptococcus mitis SK321

47.581

98.413

0.468
  comE Streptococcus infantis strain Atu-4

46.371

98.413

0.456
  comE/blpR Streptococcus mutans UA159

38.866

98.016

0.381

Multiple sequence alignment