Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   SIR_RS18205 Genome accession   NC_022246
Coordinates   1758548..1758874 (-) Length   108 a.a.
NCBI ID   WP_021003256.1    Uniprot ID   T1ZGR6
Organism   Streptococcus intermedius B196     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1753548..1763874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS18190 (SIR_1660) glmS 1754054..1755868 (-) 1815 WP_021003253.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
  SIR_RS18195 (SIR_1661) - 1756258..1757457 (-) 1200 WP_021003254.1 acetate kinase -
  SIR_RS18200 (SIR_1662) comGH 1757504..1758457 (-) 954 WP_021003255.1 class I SAM-dependent methyltransferase Machinery gene
  SIR_RS18205 (SIR_1663) comGG/cglG 1758548..1758874 (-) 327 WP_021003256.1 competence type IV pilus minor pilin ComGG Machinery gene
  SIR_RS18210 (SIR_1664) comGF/cglF 1758855..1759292 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  SIR_RS18215 (SIR_1665) comGE/cglE 1759276..1759569 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  SIR_RS18220 (SIR_1666) comGD 1759541..1759969 (-) 429 WP_021003257.1 competence type IV pilus minor pilin ComGD Machinery gene
  SIR_RS18225 (SIR_1667) comGC 1759929..1760246 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  SIR_RS18230 (SIR_1668) comGB 1760243..1761265 (-) 1023 WP_021003258.1 competence type IV pilus assembly protein ComGB Machinery gene
  SIR_RS18235 (SIR_1669) comGA 1761207..1762148 (-) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  SIR_RS18240 (SIR_1670) - 1762217..1762582 (-) 366 WP_021003259.1 DUF1033 family protein -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12912.89 Da        Isoelectric Point: 10.6199

>NTDB_id=51153 SIR_RS18205 WP_021003256.1 1758548..1758874(-) (comGG/cglG) [Streptococcus intermedius B196]
MWKQKVKAGIMLHALFMTAVFSLLLQFYLHRQTASHRNFTLNRERLQAYAMAVIANEDSRHREFDKGHVQEQQGEKELIL
TVTMKTGRHYQFRFPFEKTKLTNDNRDK

Nucleotide


Download         Length: 327 bp        

>NTDB_id=51153 SIR_RS18205 WP_021003256.1 1758548..1758874(-) (comGG/cglG) [Streptococcus intermedius B196]
GTGTGGAAACAAAAAGTTAAAGCAGGTATTATGCTCCATGCCCTTTTTATGACAGCTGTCTTTAGCTTGCTTTTGCAATT
TTATCTTCATCGTCAGACCGCTAGTCATAGAAATTTTACTCTAAACCGAGAACGACTACAGGCGTATGCAATGGCAGTTA
TCGCAAACGAAGATTCTAGACACAGAGAATTTGATAAAGGACATGTCCAAGAGCAACAAGGTGAGAAAGAGCTCATTCTG
ACAGTAACAATGAAGACAGGTCGCCATTATCAATTTCGTTTTCCGTTTGAGAAGACCAAACTAACCAATGACAATCGAGA
CAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB T1ZGR6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus mitis NCTC 12261

47.525

93.519

0.444

  comGG/cglG Streptococcus mitis SK321

43.564

93.519

0.407

  comGG/cglG Streptococcus pneumoniae Rx1

42

92.593

0.389

  comGG/cglG Streptococcus pneumoniae D39

42

92.593

0.389

  comGG/cglG Streptococcus pneumoniae R6

42

92.593

0.389

  comGG/cglG Streptococcus pneumoniae TIGR4

42

92.593

0.389


Multiple sequence alignment