Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7A_RS03040 Genome accession   NC_017857
Coordinates   650683..651930 (-) Length   415 a.a.
NCBI ID   WP_014705866.1    Uniprot ID   I1XGH2
Organism   Methylophaga nitratireducenticrescens     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 645683..656930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7A_RS03005 (Q7A_638) nadA 646418..647530 (+) 1113 WP_014705859.1 quinolinate synthase NadA -
  Q7A_RS03010 (Q7A_639) - 647548..647733 (+) 186 WP_014705860.1 zinc-finger domain-containing protein -
  Q7A_RS03015 (Q7A_640) mutT 647737..648138 (+) 402 WP_014705861.1 8-oxo-dGTP diphosphatase MutT -
  Q7A_RS03020 (Q7A_641) yacG 648195..648380 (-) 186 WP_014705862.1 DNA gyrase inhibitor YacG -
  Q7A_RS03025 (Q7A_642) zapD 648383..649153 (-) 771 WP_014705863.1 cell division protein ZapD -
  Q7A_RS03030 (Q7A_643) coaE 649199..649807 (-) 609 WP_014705864.1 dephospho-CoA kinase -
  Q7A_RS03035 (Q7A_644) pilD 649809..650678 (-) 870 WP_014705865.1 A24 family peptidase Machinery gene
  Q7A_RS03040 (Q7A_645) pilC 650683..651930 (-) 1248 WP_014705866.1 type II secretion system F family protein Machinery gene
  Q7A_RS03045 (Q7A_646) pilB 651934..653652 (-) 1719 WP_014705867.1 type IV-A pilus assembly ATPase PilB Machinery gene
  Q7A_RS03050 (Q7A_647) lptM 653858..653986 (+) 129 WP_014705868.1 LPS translocon maturation chaperone LptM -
  Q7A_RS03055 (Q7A_648) lysA 653989..655242 (+) 1254 WP_014705869.1 diaminopimelate decarboxylase -
  Q7A_RS03060 (Q7A_649) dapF 655247..656095 (+) 849 WP_014705870.1 diaminopimelate epimerase -
  Q7A_RS03065 (Q7A_650) - 656071..656781 (+) 711 WP_014705871.1 DUF484 family protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 45569.88 Da        Isoelectric Point: 10.0279

>NTDB_id=51051 Q7A_RS03040 WP_014705866.1 650683..651930(-) (pilC) [Methylophaga nitratireducenticrescens]
MATAAKAKRKPKKAELPNLFIWQGTNKSGRKVKGEQAGESVQAVRADLRRQGITPGKVRRKPKDLFAPRKPKIKPVHIAI
FSRMLATMMSSGVPMMQSLQIIGEGHENASMQEMILAIKADVESGTSLAESLAKFPLHFDDLYISLINAGEQSGTLEALL
HEIATYQEKTEALKSKIKKALVYPTAIMVVAFIVTAILMIFVIPQFQALFTGFGADLPGLTKMVISISQVFQDYWWLIFG
SIIGSVMGFMAARRRSRKVQHFMDRMLLKLPVIGDVLTKGAIARFARTFSVMFKAGVPMVEAMTSVAGATGNIVYNEATL
EMRDDVSTGTQLNKAMTDTELFPNMVIQMVSIGEESGSLDAMLAKVADFFEREVDDAVDNMTALMEPFIMAFLGVLIGTL
VIAMYLPIFKLGAVV

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=51051 Q7A_RS03040 WP_014705866.1 650683..651930(-) (pilC) [Methylophaga nitratireducenticrescens]
GTGGCCACAGCAGCTAAAGCTAAACGCAAACCTAAAAAAGCCGAATTACCGAACCTGTTTATCTGGCAAGGCACAAATAA
ATCCGGCCGGAAAGTTAAAGGTGAACAAGCGGGTGAGAGTGTTCAGGCTGTTCGTGCAGATTTACGCCGACAAGGTATTA
CGCCGGGAAAAGTACGACGCAAACCCAAGGATTTATTTGCTCCCCGCAAACCCAAAATCAAACCGGTTCACATTGCAATC
TTTAGCAGAATGCTGGCCACTATGATGTCTTCCGGTGTGCCGATGATGCAATCACTGCAAATCATTGGCGAAGGCCATGA
AAATGCCAGCATGCAGGAAATGATTCTGGCGATTAAAGCCGATGTTGAATCAGGCACCAGTCTGGCGGAGTCATTAGCCA
AATTCCCGTTACATTTTGACGATCTCTATATCAGTCTTATCAACGCCGGTGAACAGTCCGGTACGTTGGAAGCCCTTTTA
CATGAAATTGCGACCTATCAAGAAAAAACTGAAGCACTGAAATCCAAAATTAAAAAAGCGCTGGTCTACCCTACTGCCAT
TATGGTGGTGGCGTTTATCGTCACGGCGATTTTGATGATTTTTGTTATTCCACAGTTCCAGGCTTTGTTTACCGGGTTTG
GTGCGGACCTACCGGGCCTAACCAAAATGGTCATCAGCATTTCCCAGGTATTTCAGGATTACTGGTGGTTAATTTTCGGC
AGCATTATTGGTTCGGTAATGGGCTTTATGGCAGCACGACGCCGCTCTCGCAAGGTTCAGCATTTTATGGATCGTATGTT
ATTAAAATTGCCGGTTATTGGTGATGTATTAACAAAAGGTGCAATTGCCCGTTTTGCCAGAACCTTTTCGGTTATGTTCA
AAGCCGGCGTGCCAATGGTTGAGGCGATGACCTCGGTAGCGGGTGCAACGGGCAATATCGTCTACAACGAAGCGACATTG
GAAATGCGCGATGATGTCTCAACAGGTACTCAATTAAATAAAGCCATGACCGATACCGAGCTGTTCCCTAATATGGTGAT
TCAGATGGTTTCCATCGGTGAAGAATCGGGTTCTTTAGACGCGATGCTGGCAAAAGTCGCTGATTTCTTTGAGCGTGAAG
TAGATGATGCCGTTGATAATATGACCGCATTGATGGAGCCATTTATTATGGCTTTTCTCGGGGTGTTAATCGGTACGCTG
GTTATTGCAATGTACTTGCCGATTTTCAAACTCGGCGCTGTCGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(285-407)

Type II secretion system (T2SS), protein F (T2SSF)

(81-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I1XGH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

54.703

97.349

0.533
  pilC Legionella pneumophila strain ERS1305867

54.293

95.422

0.518
  pilC Acinetobacter baylyi ADP1

50.617

97.59

0.494
  pilC Acinetobacter baumannii D1279779

49.136

97.59

0.48
  pilG Neisseria gonorrhoeae MS11

44.332

95.663

0.424
  pilG Neisseria meningitidis 44/76-A

44.081

95.663

0.422
  pilC Vibrio cholerae strain A1552

40.909

95.422

0.39
  pilC Vibrio campbellii strain DS40M4

39.401

96.627

0.381

Multiple sequence alignment