Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ST1A_RS08925 Genome accession   NZ_CP065384
Coordinates   1725858..1726799 (-) Length   313 a.a.
NCBI ID   WP_014622005.1    Uniprot ID   A0A2X3UX10
Organism   Streptococcus thermophilus strain 1A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1720858..1731799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST1A_RS08885 (ST1A_08815) - 1720934..1722127 (-) 1194 WP_014608740.1 acetate kinase -
  ST1A_RS08890 (ST1A_08820) comYH 1722183..1723139 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  ST1A_RS08895 (ST1A_08825) comGG 1723184..1723501 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG -
  ST1A_RS08900 (ST1A_08830) comYF 1723479..1723916 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  ST1A_RS08905 (ST1A_08835) comGE 1723900..1724193 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  ST1A_RS08910 (ST1A_08840) comYD 1724165..1724593 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  ST1A_RS08915 (ST1A_08845) comYC 1724553..1724879 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ST1A_RS08920 (ST1A_08850) comYB 1724876..1725976 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  ST1A_RS08925 (ST1A_08855) comYA 1725858..1726799 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  ST1A_RS08930 (ST1A_08860) - 1726880..1727242 (-) 363 WP_023909982.1 DUF1033 family protein -
  ST1A_RS08935 (ST1A_08865) rpoC 1727401..1731039 (-) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35421.62 Da        Isoelectric Point: 6.3927

>NTDB_id=509117 ST1A_RS08925 WP_014622005.1 1725858..1726799(-) (comYA) [Streptococcus thermophilus strain 1A]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGACDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQVIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=509117 ST1A_RS08925 WP_014622005.1 1725858..1726799(-) (comYA) [Streptococcus thermophilus strain 1A]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTGCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGTGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGGGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3UX10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

51.768

99.361

0.514
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377