Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SMULJ23_RS09370 Genome accession   NC_017768
Coordinates   1924171..1925427 (-) Length   418 a.a.
NCBI ID   WP_014678282.1    Uniprot ID   -
Organism   Streptococcus mutans LJ23     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1919171..1930427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS09330 (SMULJ23_1821) - 1919362..1919661 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  SMULJ23_RS09335 (SMULJ23_1822) ruvX 1919742..1920161 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  SMULJ23_RS09340 (SMULJ23_1823) - 1920158..1920427 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMULJ23_RS09345 (SMULJ23_1824) brsR 1920595..1921029 (+) 435 Protein_1817 bacteriocin genes transcriptional regulator BrsR -
  SMULJ23_RS09350 (SMULJ23_1825) brsM 1921042..1921488 (+) 447 WP_014678281.1 bacteriocin genes regulator BrsM Regulator
  SMULJ23_RS10295 - 1921479..1921691 (-) 213 Protein_1819 hypothetical protein -
  SMULJ23_RS09355 (SMULJ23_1826) - 1921820..1922245 (-) 426 WP_002271571.1 hypothetical protein -
  SMULJ23_RS09360 (SMULJ23_1827) spx 1922497..1922895 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMULJ23_RS09365 (SMULJ23_1828) recA 1922980..1924131 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMULJ23_RS09370 (SMULJ23_1829) cinA 1924171..1925427 (-) 1257 WP_014678282.1 competence/damage-inducible protein A Machinery gene
  SMULJ23_RS09375 (SMULJ23_1830) - 1925576..1926136 (-) 561 WP_014678283.1 DNA-3-methyladenine glycosylase I -
  SMULJ23_RS09380 (SMULJ23_1831) ruvA 1926218..1926811 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  SMULJ23_RS09385 (SMULJ23_1832) mutL 1926994..1928949 (-) 1956 WP_014678284.1 DNA mismatch repair endonuclease MutL -
  SMULJ23_RS10300 - 1929174..1929452 (+) 279 Protein_1827 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45727.52 Da        Isoelectric Point: 6.4066

>NTDB_id=50789 SMULJ23_RS09370 WP_014678282.1 1924171..1925427(-) (cinA) [Streptococcus mutans LJ23]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSHPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=50789 SMULJ23_RS09370 WP_014678282.1 1924171..1925427(-) (cinA) [Streptococcus mutans LJ23]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGCGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACGCCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCATCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(259-411)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.522

100

0.995
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.231

98.325

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452

Multiple sequence alignment