Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SMULJ23_RS01070 Genome accession   NC_017768
Coordinates   250043..251074 (+) Length   343 a.a.
NCBI ID   WP_255264922.1    Uniprot ID   -
Organism   Streptococcus mutans LJ23     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 245043..256074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS01060 (SMULJ23_0192) - 248653..249036 (+) 384 WP_002263434.1 DUF1033 family protein -
  SMULJ23_RS01065 (SMULJ23_0193) comYA 249166..250107 (+) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  SMULJ23_RS01070 (SMULJ23_0194) comYB 250043..251074 (+) 1032 WP_255264922.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMULJ23_RS01075 (SMULJ23_0195) comYC 251074..251388 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMULJ23_RS01080 (SMULJ23_0196) comYD 251375..251779 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMULJ23_RS01085 (SMULJ23_0197) comYE 251751..252044 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMULJ23_RS01090 (SMULJ23_0198) comYF 252031..252465 (+) 435 WP_002274770.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMULJ23_RS01095 (SMULJ23_0199) comYG 252443..252832 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMULJ23_RS01100 (SMULJ23_0200) comYH 252887..253840 (+) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  SMULJ23_RS01105 (SMULJ23_0201) - 253899..255098 (+) 1200 WP_002263443.1 acetate kinase -
  SMULJ23_RS01110 tnpA 255311..255774 (+) 464 Protein_198 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39842.48 Da        Isoelectric Point: 9.4874

>NTDB_id=50730 SMULJ23_RS01070 WP_255264922.1 250043..251074(+) (comYB) [Streptococcus mutans LJ23]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLEKGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSYLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=50730 SMULJ23_RS01070 WP_255264922.1 250043..251074(+) (comYB) [Streptococcus mutans LJ23]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTAGGATTAAAGAATTATTTATTACCACAACTTGAAAAGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTTCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCTATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

99.417

100

0.994
  comYB Streptococcus mutans UA140

99.417

100

0.994
  comYB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.929

98.251

0.51

Multiple sequence alignment