Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SCI_RS09445 Genome accession   NC_022238
Coordinates   1886123..1887391 (-) Length   422 a.a.
NCBI ID   WP_020998093.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. pharyngis C1050     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1881123..1892391
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCI_RS09410 (SCI_1835) - 1882014..1882319 (-) 306 WP_006269082.1 DUF1292 domain-containing protein -
  SCI_RS09415 (SCI_1836) ruvX 1882337..1882756 (-) 420 WP_003071469.1 Holliday junction resolvase RuvX -
  SCI_RS09420 (SCI_1837) - 1882756..1883022 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  SCI_RS11075 - 1883146..1883481 (-) 336 WP_006268977.1 SP0191 family lipoprotein -
  SCI_RS09430 (SCI_1838) - 1883807..1884307 (-) 501 WP_006269036.1 SP0191 family lipoprotein -
  SCI_RS09435 (SCI_1839) spx 1884444..1884842 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  SCI_RS09440 (SCI_1840) recA 1884929..1886074 (-) 1146 WP_020998092.1 recombinase RecA -
  SCI_RS09445 (SCI_1841) cinA 1886123..1887391 (-) 1269 WP_020998093.1 competence/damage-inducible protein A Machinery gene
  SCI_RS09450 (SCI_1842) - 1887547..1888176 (-) 630 WP_020998094.1 ABC transporter ATP-binding protein -
  SCI_RS09455 (SCI_1843) - 1888173..1890182 (-) 2010 WP_020998095.1 hypothetical protein -
  SCI_RS10400 (SCI_1844) - 1890280..1890549 (-) 270 WP_020998096.1 hypothetical protein -
  SCI_RS09460 (SCI_1845) - 1890932..1891786 (+) 855 WP_006269187.1 Rgg/GadR/MutR family transcriptional regulator -
  SCI_RS09465 (SCI_1846) - 1891947..1892360 (+) 414 WP_006269778.1 EamA family transporter -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 46083.81 Da        Isoelectric Point: 5.6090

>NTDB_id=50674 SCI_RS09445 WP_020998093.1 1886123..1887391(-) (cinA) [Streptococcus constellatus subsp. pharyngis C1050]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSILEIAKKRSDLVILCGGLGPTEDDLTKQV
LAKFLNRRLVFDQVAMEKLDRFFASRLDYVRTPNNERQAQIVEDSTSLQNETGLAVGGVIEVSGVTYVVLPGPPSELKPM
VNNELIPILATDQKLYSRVLRFFGIGESQLVTLLGDLIDAQIDPTIAPYAKTGEVTLRLSTKASSQKEADTKFAYLEKKI
LAVQTFEKQRLVDLFYAYGDDNSLAQTTFELLRRAGKTVTAAESLTAGLFQATLANFSGASNVFSGGFVTYSMEEKSRML
DIPLADLEKHGVVSAFTAKKMAEQARKLTASDYAVSLTGVAGPDSLEGYPAGTVYIGLATTENVQSFKVNIAGRSRTDVR
KIAVLHAFNQLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=50674 SCI_RS09445 WP_020998093.1 1886123..1887391(-) (cinA) [Streptococcus constellatus subsp. pharyngis C1050]
ATGAAAGCAGAAATTATTGCTGTAGGTACTGAAATTCTGACCGGGCAAATTGTCAATACGAATGCTCAATTTTTATCGGA
AAAATTAGCTAGTTTAGGGATTGATGTTTATTTCCAGACTGCTGTCGGTGACAATGAAAATCGTCTTTTATCTATTTTGG
AAATTGCAAAGAAACGGAGCGATCTTGTCATTCTTTGTGGTGGCTTGGGTCCAACAGAAGATGACTTGACCAAACAGGTG
TTGGCAAAATTTTTAAATCGCAGGTTGGTCTTTGACCAAGTAGCTATGGAAAAATTAGATCGTTTCTTCGCGAGTCGACT
GGACTATGTTCGAACACCAAATAATGAGCGGCAAGCTCAGATAGTGGAAGATTCGACTTCTCTACAAAACGAAACCGGAC
TTGCGGTAGGGGGTGTGATTGAAGTAAGTGGTGTAACTTATGTTGTTCTGCCCGGTCCACCTAGTGAATTAAAACCTATG
GTGAACAATGAGCTGATTCCGATTTTAGCAACGGATCAAAAATTGTATTCAAGAGTTTTGCGCTTCTTTGGCATTGGTGA
AAGTCAATTAGTAACTCTTTTAGGAGATTTAATTGATGCTCAGATCGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACAAAGGCTAGCAGTCAAAAAGAAGCAGATACTAAGTTTGCTTATTTGGAAAAGAAAATT
TTAGCTGTACAGACTTTTGAGAAACAACGTTTAGTGGACCTTTTCTATGCTTATGGAGATGATAATTCTCTAGCGCAGAC
AACTTTTGAATTGTTGAGGAGAGCAGGCAAGACTGTTACAGCAGCCGAAAGTTTGACTGCAGGCCTTTTTCAAGCAACTT
TGGCAAACTTTTCTGGAGCCTCTAATGTCTTTAGTGGTGGCTTTGTCACTTACAGTATGGAGGAAAAGAGCCGCATGCTG
GACATTCCTTTGGCAGACTTGGAAAAACATGGAGTTGTTTCTGCTTTTACAGCAAAGAAAATGGCTGAGCAGGCCAGAAA
ATTGACTGCCAGTGACTATGCAGTGAGTTTGACGGGTGTGGCAGGTCCAGACAGCTTAGAAGGATATCCGGCAGGGACAG
TTTATATTGGCTTAGCAACCACAGAGAATGTACAATCTTTTAAGGTTAATATTGCCGGTCGTAGTCGGACTGATGTACGA
AAAATAGCTGTTCTGCATGCTTTCAATCAGTTACGAAAAACTTTATTAAAAAACGAAAATATGCTATAA

Domains

Predicted by InterProScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.641

99.052

0.739
  cinA Streptococcus pneumoniae TIGR4

74.163

99.052

0.735
  cinA Streptococcus pneumoniae R36A

74.163

99.052

0.735
  cinA Streptococcus pneumoniae Rx1

74.163

99.052

0.735
  cinA Streptococcus pneumoniae R6

74.163

99.052

0.735
  cinA Streptococcus pneumoniae D39

73.923

99.052

0.732
  cinA Streptococcus mitis NCTC 12261

73.684

99.052

0.73
  cinA Streptococcus mutans UA159

71.395

100

0.716
  cinA Streptococcus suis isolate S10

55.288

98.578

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

44.976

99.052

0.445

Multiple sequence alignment