Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   IVG45_RS19470 Genome accession   NZ_CP064653
Coordinates   4156660..4157877 (+) Length   405 a.a.
NCBI ID   WP_196435422.1    Uniprot ID   A0A7T0NWN7
Organism   Methylomonas sp. LL1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4151660..4162877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IVG45_RS19455 (IVG45_19410) - 4152593..4154023 (+) 1431 WP_230874661.1 HDOD domain-containing protein -
  IVG45_RS19460 (IVG45_19415) - 4154026..4154817 (+) 792 WP_230874662.1 response regulator -
  IVG45_RS19465 (IVG45_19420) pilB 4154947..4156656 (+) 1710 WP_196435421.1 type IV-A pilus assembly ATPase PilB Machinery gene
  IVG45_RS19470 (IVG45_19425) pilC 4156660..4157877 (+) 1218 WP_196435422.1 type II secretion system F family protein Machinery gene
  IVG45_RS19475 (IVG45_19430) pilD 4157956..4158819 (+) 864 WP_196435423.1 A24 family peptidase Machinery gene
  IVG45_RS19480 (IVG45_19435) coaE 4158823..4159434 (+) 612 WP_196435424.1 dephospho-CoA kinase -
  IVG45_RS19485 (IVG45_19440) zapD 4159431..4160201 (+) 771 WP_196435425.1 cell division protein ZapD -
  IVG45_RS19490 (IVG45_19445) yacG 4160201..4160404 (+) 204 WP_196435426.1 DNA gyrase inhibitor YacG -
  IVG45_RS19495 (IVG45_19450) - 4160419..4161351 (-) 933 WP_196435427.1 Nudix family hydrolase -
  IVG45_RS19500 (IVG45_19455) argJ 4161352..4162566 (-) 1215 WP_196435428.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
  IVG45_RS19505 (IVG45_19460) - 4162588..4162863 (-) 276 WP_230874663.1 sulfurtransferase TusA family protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44172.10 Da        Isoelectric Point: 7.8236

>NTDB_id=504056 IVG45_RS19470 WP_196435422.1 4156660..4157877(+) (pilC) [Methylomonas sp. LL1]
MAKQTEQIDFIWEGLDKQGKKTGGMISAKSDAIARTELRKMGVRVIKIKPKPKPLFGKAAQKITSGDIAVFARQLATMLE
AGVPLVQSFDIIGKGHDNASMSEMLLSIKADIEGGDTLAQALAKKPLYFDDLFCNLVNAGEQAGVLEGLLDKIATYKEKT
ESIRKKVKKALTYPIAVLVVAFIVTAILLIFVVPVFQELFQGFGADLPAFTKFVVALSEWVKEWWWSVVGVIGAAGYTFS
FFKKRSRPFNHFLDRTLLKIPVVGMILEKSAIARFARTLSTMSAAGVPLVDALVSVAGACGNILFYDGVMKMRDDVSTGQ
QLQFSMIQTGLFPNMVVQMVAIGEESGSIDSMLDKVADFYEEEVDNLVDNLSSLMEPIIMSVLGVLIGGLIVAMYLPIFK
MGSAI

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=504056 IVG45_RS19470 WP_196435422.1 4156660..4157877(+) (pilC) [Methylomonas sp. LL1]
ATGGCCAAACAAACAGAACAAATCGACTTTATTTGGGAAGGTCTCGACAAGCAGGGTAAAAAAACCGGTGGGATGATCAG
CGCCAAGAGTGATGCCATCGCCCGCACGGAGTTGAGAAAAATGGGGGTTAGGGTGATCAAGATCAAACCCAAACCCAAGC
CTCTGTTTGGGAAAGCCGCTCAGAAAATCACCTCCGGCGACATTGCGGTTTTTGCCCGTCAGTTGGCCACCATGCTGGAG
GCCGGGGTACCGCTGGTGCAGTCGTTCGATATTATCGGTAAGGGGCATGATAATGCCAGTATGTCGGAAATGTTGCTGTC
GATTAAGGCCGACATCGAAGGCGGCGATACCCTGGCCCAGGCCTTGGCTAAAAAACCGCTTTATTTTGATGATTTGTTCT
GCAATCTGGTGAATGCCGGCGAGCAAGCCGGTGTCTTGGAAGGCTTGCTGGACAAGATCGCTACCTATAAGGAAAAAACC
GAGTCTATCCGGAAAAAGGTTAAAAAGGCCTTGACCTATCCGATTGCGGTATTAGTAGTGGCCTTCATTGTCACGGCCAT
TTTGTTGATTTTCGTGGTGCCGGTATTTCAAGAATTGTTTCAAGGCTTTGGGGCCGATCTGCCTGCGTTTACAAAGTTTG
TCGTTGCTTTGTCGGAGTGGGTGAAAGAATGGTGGTGGAGCGTGGTCGGTGTAATCGGTGCGGCCGGTTACACCTTCAGT
TTCTTCAAGAAGCGTTCCCGTCCTTTCAATCATTTCCTAGATCGAACCCTATTAAAGATCCCCGTGGTAGGCATGATTCT
GGAAAAATCCGCGATTGCCCGCTTTGCCCGAACCTTGTCCACCATGTCGGCGGCCGGCGTGCCGTTGGTGGATGCATTGG
TTTCGGTGGCGGGGGCGTGCGGAAACATCTTGTTCTACGACGGCGTGATGAAAATGCGGGATGATGTCTCGACCGGACAG
CAGCTGCAATTTTCGATGATACAGACCGGATTGTTCCCGAACATGGTGGTGCAGATGGTGGCGATTGGGGAAGAGTCCGG
ATCGATAGACAGTATGCTGGACAAAGTGGCCGATTTTTACGAGGAAGAAGTCGACAATTTGGTTGATAACCTGAGTAGTT
TGATGGAACCCATCATCATGTCGGTGCTGGGCGTATTGATCGGGGGCTTGATAGTGGCTATGTATTTACCTATTTTCAAA
ATGGGTAGCGCGATCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T0NWN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

59.446

98.025

0.583
  pilC Legionella pneumophila strain ERS1305867

59.296

98.272

0.583
  pilC Acinetobacter baumannii D1279779

55.164

98.025

0.541
  pilC Acinetobacter baylyi ADP1

52.709

100

0.528
  pilG Neisseria meningitidis 44/76-A

47.5

98.765

0.469
  pilG Neisseria gonorrhoeae MS11

47.25

98.765

0.467
  pilC Vibrio cholerae strain A1552

40.1

98.519

0.395
  pilC Vibrio campbellii strain DS40M4

38.903

99.012

0.385