Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   IUH68_RS12405 Genome accession   NZ_CP064406
Coordinates   2482982..2484223 (-) Length   413 a.a.
NCBI ID   WP_002318846.1    Uniprot ID   -
Organism   Enterococcus faecium strain PR05720-3     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2477982..2489223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IUH68_RS12390 (IUH68_12390) proC 2478972..2479778 (+) 807 WP_002318848.1 pyrroline-5-carboxylate reductase -
  IUH68_RS12395 (IUH68_12395) rny 2479857..2481413 (-) 1557 WP_002287336.1 ribonuclease Y -
  IUH68_RS12400 (IUH68_12400) recA 2481824..2482873 (-) 1050 WP_002318847.1 recombinase RecA Machinery gene
  IUH68_RS12405 (IUH68_12405) cinA 2482982..2484223 (-) 1242 WP_002318846.1 competence/damage-inducible protein A Machinery gene
  IUH68_RS12410 (IUH68_12410) pgsA 2484463..2485041 (-) 579 WP_002298210.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IUH68_RS12415 (IUH68_12415) - 2485250..2486173 (-) 924 WP_080129768.1 RodZ domain-containing protein -
  IUH68_RS12420 (IUH68_12420) - 2486912..2488198 (-) 1287 WP_002318844.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45414.78 Da        Isoelectric Point: 4.6941

>NTDB_id=501916 IUH68_RS12405 WP_002318846.1 2482982..2484223(-) (cinA) [Enterococcus faecium strain PR05720-3]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDNNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=501916 IUH68_RS12405 WP_002318846.1 2482982..2484223(-) (cinA) [Enterococcus faecium strain PR05720-3]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATAATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGTGCCTTCCAAGCCGCATTGGGCGATATTG
CTGGTGTATCTGAAGTATTTCCAGGTGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTAGTTTCAGAAAAATATCACTTTGCCAGAGACCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-410)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Streptococcus pneumoniae TIGR4

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.714

100

0.516
  cinA Streptococcus pneumoniae R6

50.714

100

0.516
  cinA Streptococcus pneumoniae Rx1

50.714

100

0.516
  cinA Streptococcus mitis NCTC 12261

50.714

100

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

47.33

99.758

0.472
  cinA Streptococcus suis isolate S10

41.546

100

0.416